Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2589173..2589318 Replicon chromosome
Accession NZ_CP035531
Organism Klebsiella pneumoniae strain NFYY0065

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2589180..2589282 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2589173..2589318 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EI683_RS12910 2584704..2586137 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
EI683_RS12915 2586253..2586492 + 240 WP_002911393.1 YebV family protein -
EI683_RS12920 2586590..2586781 + 192 WP_002911395.1 YebW family protein -
EI683_RS12925 2586778..2587431 - 654 WP_009307541.1 protein-serine/threonine phosphatase -
EI683_RS12930 2587588..2588556 + 969 WP_004151446.1 VirK/YbjX family protein -
EI683_RS26485 2588661..2588804 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 2589173..2589318 + 146 - - Antitoxin
- 2589180..2589282 - 103 - - Toxin
EI683_RS12940 2589441..2589779 - 339 WP_009307539.1 YebY family protein -
EI683_RS12945 2589796..2590665 - 870 WP_009307538.1 copper homeostasis membrane protein CopD -
EI683_RS12950 2590669..2591043 - 375 WP_004151448.1 CopC domain-containing protein YobA -
EI683_RS12955 2591156..2591386 + 231 WP_002911406.1 DNA polymerase III subunit theta -
EI683_RS12960 2591465..2592124 + 660 WP_002911407.1 exodeoxyribonuclease X -
EI683_RS12965 2592128..2594188 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T118069 NZ_CP035531:c2589282-2589180 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT118069 NZ_CP035531:2589173-2589318 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References