Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1977309..1977577 Replicon chromosome
Accession NZ_CP035516
Organism Escherichia coli strain U14A

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1977347..1977449 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1977309..1977577 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
U14A_RS10005 1974467..1975906 + 1440 WP_001296139.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
U14A_RS10010 1976023..1976259 + 237 WP_001295499.1 DUF1480 family protein -
U14A_RS10015 1976364..1976555 + 192 WP_001296140.1 YebW family protein -
U14A_RS10020 1976556..1977212 - 657 WP_000812745.1 protein-serine/threonine phosphatase -
- 1977309..1977577 + 269 - - Antitoxin
- 1977347..1977449 - 103 - - Toxin
U14A_RS10025 1977607..1977948 - 342 WP_000976472.1 YebY family protein -
U14A_RS10030 1977961..1978833 - 873 WP_000879317.1 copper homeostasis membrane protein CopD -
U14A_RS10035 1978837..1979211 - 375 WP_000168747.1 CopC domain-containing protein YobA -
U14A_RS10040 1979350..1979580 + 231 WP_000916763.1 DNA polymerase III subunit theta -
U14A_RS10045 1979682..1980338 + 657 WP_000011664.1 carbon-nitrogen hydrolase family protein -
U14A_RS10050 1980362..1981024 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T118031 NZ_CP035516:c1977449-1977347 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT118031 NZ_CP035516:1977309-1977577 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATATTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References