Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 1302894..1303531 Replicon chromosome
Accession NZ_CP035504
Organism Kocuria indica strain CE7

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag KocCE7_RS05865 Protein ID WP_098054436.1
Coordinates 1302894..1303313 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag KocCE7_RS05870 Protein ID WP_131332832.1
Coordinates 1303304..1303531 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KocCE7_RS05840 1298654..1299418 - 765 WP_131332828.1 thioesterase II family protein -
KocCE7_RS05845 1299750..1300271 + 522 WP_064846797.1 Cys-tRNA(Pro) deacylase -
KocCE7_RS05850 1300665..1301114 + 450 Protein_1147 enoyl-CoA hydratase/isomerase family protein -
KocCE7_RS05855 1301535..1302221 + 687 WP_131332830.1 SDR family NAD(P)-dependent oxidoreductase -
KocCE7_RS05860 1302104..1302439 - 336 WP_206399173.1 antibiotic biosynthesis monooxygenase -
KocCE7_RS05865 1302894..1303313 - 420 WP_098054436.1 PIN domain nuclease Toxin
KocCE7_RS05870 1303304..1303531 - 228 WP_131332832.1 hypothetical protein Antitoxin
KocCE7_RS05875 1303721..1304131 + 411 WP_064846804.1 hypothetical protein -
KocCE7_RS05880 1304234..1307887 + 3654 WP_131333918.1 DNA polymerase III subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 15078.45 Da        Isoelectric Point: 6.7202

>T118018 WP_098054436.1 NZ_CP035504:c1303313-1302894 [Kocuria indica]
VAVTGWLIDKSAYARMQAGKAAHLEDWNARIERGLVRLSTVTRLELGFSSRSGEGGRQAFGLPPLSLMPIEHLTPAMEDR
AFQVQMLLADRGQHRAPSIPDLLIAACAEKAGLTVLAMDKDFDLIAAVTGQPVETLTLR

Download         Length: 420 bp

>T118018 NZ_CP035504:c1303313-1302894 [Kocuria indica]
GTGGCAGTGACCGGCTGGTTAATTGACAAGTCTGCGTATGCACGAATGCAGGCAGGGAAGGCCGCGCACCTTGAGGACTG
GAATGCCCGCATCGAACGAGGACTGGTTCGACTCTCGACGGTCACGCGGCTTGAACTGGGATTCTCATCCCGTTCCGGCG
AAGGCGGGCGTCAGGCGTTCGGGCTGCCGCCGCTGTCGCTGATGCCCATCGAACATCTGACGCCCGCGATGGAGGACCGT
GCCTTCCAGGTGCAGATGTTGCTCGCCGATAGAGGTCAGCATCGTGCGCCGTCCATTCCGGATCTGCTGATCGCAGCATG
TGCAGAGAAGGCTGGGCTGACGGTGCTGGCCATGGACAAGGACTTCGACTTGATTGCCGCGGTCACAGGCCAGCCGGTGG
AAACCCTCACGCTGCGATGA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8369.33 Da        Isoelectric Point: 4.3063

>AT118018 WP_131332832.1 NZ_CP035504:c1303531-1303304 [Kocuria indica]
MKNVLIRGLSDRAVESIDAEASALGLSRNEFLRRKFETAAAMTDDKATVTTEDWERSSRAFGDLMDDDIMAAAWQ

Download         Length: 228 bp

>AT118018 NZ_CP035504:c1303531-1303304 [Kocuria indica]
ATGAAGAATGTCCTCATCCGGGGACTCAGTGACAGGGCGGTTGAAAGCATCGATGCGGAGGCATCCGCGCTGGGGCTATC
CCGCAACGAGTTCCTGCGCCGGAAGTTCGAGACAGCGGCAGCCATGACGGACGACAAGGCCACGGTGACCACTGAGGACT
GGGAGCGCTCCTCCCGCGCCTTCGGCGACCTCATGGATGACGACATCATGGCTGCCGCGTGGCAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References