Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 3912594..3913243 Replicon chromosome
Accession NZ_CP035503
Organism Rhodoferax sediminis strain CHu59-6-5

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag EUB48_RS18880 Protein ID WP_210411770.1
Coordinates 3912594..3913001 (-) Length 136 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag EUB48_RS18885 Protein ID WP_142820630.1
Coordinates 3913010..3913243 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EUB48_RS18860 3908324..3909505 - 1182 WP_142820626.1 hypothetical protein -
EUB48_RS18865 3909530..3911470 - 1941 WP_142820627.1 polysaccharide biosynthesis protein -
EUB48_RS18870 3911506..3911925 - 420 WP_142820628.1 hypothetical protein -
EUB48_RS18875 3911903..3912493 - 591 WP_142820629.1 transcriptional regulator -
EUB48_RS18880 3912594..3913001 - 408 WP_210411770.1 PIN domain-containing protein Toxin
EUB48_RS18885 3913010..3913243 - 234 WP_142820630.1 antitoxin Antitoxin
EUB48_RS18890 3913338..3913784 - 447 Protein_3725 sugar transferase -
EUB48_RS18895 3913811..3914986 - 1176 WP_142820631.1 DegT/DnrJ/EryC1/StrS aminotransferase family protein -
EUB48_RS18900 3914990..3915649 - 660 WP_142820632.1 NeuD/PglB/VioB family sugar acetyltransferase -
EUB48_RS18905 3915646..3916251 - 606 WP_142820633.1 sugar transferase -
EUB48_RS18910 3916248..3917366 - 1119 WP_142820634.1 glycosyltransferase family 4 protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3911903..3925760 13857


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-120)

Antitoxin

SpoVT-AbrB domain

(7-44)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 14723.81 Da        Isoelectric Point: 5.8625

>T118016 WP_210411770.1 NZ_CP035503:c3913001-3912594 [Rhodoferax sediminis]
MLDTNICIYVINARPPAVLARFRQERMGNIGISSVTAAELAFGVAKSGSARNREALEMFLAPLDVLPFDASTIWQYGELR
AGLERRGQPIGALDTMIAAHALASNTVLVTNNTREFARVPGLRLENWADEPPNSN

Download         Length: 408 bp

>T118016 NZ_CP035503:c3913001-3912594 [Rhodoferax sediminis]
ATGCTGGACACCAATATTTGCATTTATGTGATCAATGCCCGGCCGCCTGCGGTGTTGGCGCGCTTCAGGCAGGAGCGCAT
GGGGAATATCGGCATTTCCAGCGTCACGGCCGCGGAGTTGGCCTTTGGAGTGGCCAAAAGCGGTTCCGCTCGCAACCGGG
AGGCGCTGGAGATGTTCCTGGCGCCGCTGGACGTCCTGCCTTTTGACGCCTCCACTATTTGGCAGTATGGGGAGTTGCGC
GCAGGACTGGAGCGACGCGGCCAGCCCATCGGCGCACTTGACACGATGATCGCCGCCCATGCGCTGGCGTCCAATACCGT
CCTGGTGACTAACAACACCCGCGAATTCGCCCGGGTGCCAGGGTTGCGGCTTGAGAATTGGGCGGATGAGCCGCCAAATT
CCAATTAA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8572.68 Da        Isoelectric Point: 4.7023

>AT118016 WP_142820630.1 NZ_CP035503:c3913243-3913010 [Rhodoferax sediminis]
MDTARLFQSGRSQAVRLPKEYRFEGVEVAVRHFGNGVLLLPVNEPWAMLDAALDAFEPGFQISRDQPAAQAREEIAS

Download         Length: 234 bp

>AT118016 NZ_CP035503:c3913243-3913010 [Rhodoferax sediminis]
ATGGATACCGCACGTCTTTTTCAGTCGGGGCGCAGCCAGGCGGTTCGTCTGCCCAAAGAGTACCGTTTTGAGGGCGTGGA
GGTCGCTGTGCGGCATTTCGGAAACGGAGTCTTGCTGCTGCCGGTGAATGAGCCTTGGGCCATGCTTGACGCGGCGCTGG
ACGCTTTCGAGCCGGGGTTTCAGATCAGCCGCGATCAGCCCGCCGCGCAGGCCCGCGAGGAGATCGCGTCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References