Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 2972103..2972699 Replicon chromosome
Accession NZ_CP035503
Organism Rhodoferax sediminis strain CHu59-6-5

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag EUB48_RS14370 Protein ID WP_142819782.1
Coordinates 2972103..2972399 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag EUB48_RS14375 Protein ID WP_142819784.1
Coordinates 2972403..2972699 (+) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EUB48_RS14355 2967327..2968409 + 1083 WP_210411638.1 ACR3 family arsenite efflux transporter -
EUB48_RS14360 2968647..2971232 + 2586 WP_142819780.1 DNA mismatch repair protein MutS -
EUB48_RS21510 2971340..2972065 + 726 WP_210411639.1 hypothetical protein -
EUB48_RS14370 2972103..2972399 + 297 WP_142819782.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EUB48_RS14375 2972403..2972699 + 297 WP_142819784.1 putative addiction module antidote protein Antitoxin
EUB48_RS14380 2972696..2973523 + 828 WP_142819786.1 proteasome-type protease -
EUB48_RS14385 2973606..2974424 + 819 WP_142819788.1 alpha/beta hydrolase -
EUB48_RS14390 2974429..2976249 - 1821 WP_142819789.1 DUF1446 domain-containing protein -
EUB48_RS14395 2976274..2977053 - 780 WP_142819790.1 enoyl-CoA hydratase/isomerase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-96)

Antitoxin

Uncharacterized protein HI1420

(3-95)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11288.09 Da        Isoelectric Point: 10.0877

>T118014 WP_142819782.1 NZ_CP035503:2972103-2972399 [Rhodoferax sediminis]
MFEIIKTETFEHWLLDLKDRMARFRIQARVDRLASGNTGDFKPLRNGISELRIDFGPGYRVYFMRSGPLVIVLLAGGDKR
TQDADIERAIAMAKDWKA

Download         Length: 297 bp

>T118014 NZ_CP035503:2972103-2972399 [Rhodoferax sediminis]
ATGTTCGAGATCATCAAGACGGAAACCTTCGAGCACTGGCTGCTTGACCTGAAAGACCGGATGGCGCGTTTTCGAATTCA
GGCTCGCGTTGACAGGTTGGCCAGCGGCAACACTGGAGATTTCAAGCCTTTGCGCAATGGCATTTCCGAGTTGCGCATTG
ACTTTGGCCCCGGCTACCGGGTGTATTTCATGCGCAGTGGCCCGCTGGTGATCGTGCTCCTGGCGGGCGGTGACAAGCGC
ACACAGGATGCTGACATCGAGCGCGCGATTGCAATGGCGAAAGACTGGAAGGCGTAA

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10780.17 Da        Isoelectric Point: 4.5482

>AT118014 WP_142819784.1 NZ_CP035503:2972403-2972699 [Rhodoferax sediminis]
MTEKFSRWDSADYLKTEEDIDLYFEACLEEDPGDGSLIRSALGAIARARGMSQLARDTGLAREGLYKALSPEGNPEFSTV
MRVIKALGLKLSVQAEHA

Download         Length: 297 bp

>AT118014 NZ_CP035503:2972403-2972699 [Rhodoferax sediminis]
ATGACTGAGAAATTCTCCCGCTGGGATAGCGCGGACTACCTCAAAACCGAAGAAGACATTGATTTGTATTTTGAAGCCTG
TCTTGAGGAAGATCCCGGCGACGGTAGCCTGATCCGCAGCGCGCTGGGCGCCATTGCCCGCGCGCGCGGAATGAGCCAGC
TGGCGCGGGACACGGGCCTTGCGCGCGAGGGCCTGTACAAGGCGTTGTCCCCCGAAGGCAACCCCGAGTTCTCCACGGTG
ATGCGGGTGATCAAGGCGCTGGGCCTGAAGCTCAGCGTGCAGGCGGAGCACGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References