Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 4600081..4600742 Replicon chromosome
Accession NZ_CP035501
Organism Sphingosinicella sp. BN140058

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag ETR14_RS20780 Protein ID WP_165356554.1
Coordinates 4600081..4600377 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag ETR14_RS20785 Protein ID WP_129388396.1
Coordinates 4600470..4600742 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ETR14_RS20760 4595812..4597305 - 1494 WP_129388381.1 glucose-6-phosphate isomerase -
ETR14_RS20765 4597438..4598256 + 819 WP_129388384.1 signal peptidase I -
ETR14_RS20775 4598732..4599808 + 1077 WP_129388390.1 GTPase Era -
ETR14_RS20780 4600081..4600377 - 297 WP_165356554.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ETR14_RS20785 4600470..4600742 - 273 WP_129388396.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
ETR14_RS20790 4600889..4603126 - 2238 WP_129388399.1 catalase/peroxidase HPI -
ETR14_RS20795 4603289..4604002 - 714 WP_129388402.1 NAD-dependent deacylase -
ETR14_RS20800 4604112..4604756 + 645 WP_129388405.1 response regulator transcription factor -
ETR14_RS20805 4604903..4605271 + 369 WP_129388407.1 response regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-93)

Antitoxin

Antitoxin ParD

(1-78)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11037.63 Da        Isoelectric Point: 10.4044

>T118012 WP_165356554.1 NZ_CP035501:c4600377-4600081 [Sphingosinicella sp. BN140058]
VARRLEFTRKASADIEGIWAYTSRRWGAEQAQRYVSTIRDRCRALAGGEFPATQVDVGGRLFLKLRAGSHVIFGLETEAM
FLVVRILHVRQDPDTGFA

Download         Length: 297 bp

>T118012 NZ_CP035501:c4600377-4600081 [Sphingosinicella sp. BN140058]
GTGGCGCGGCGGCTTGAATTCACCCGCAAAGCCAGCGCGGACATTGAAGGAATCTGGGCATATACGAGCCGGCGATGGGG
AGCCGAGCAGGCGCAACGTTACGTGAGCACGATCCGGGACCGCTGCCGTGCACTGGCAGGTGGCGAGTTCCCCGCTACGC
AAGTGGACGTCGGCGGCAGGCTGTTCCTCAAGTTACGAGCGGGTTCACATGTCATCTTCGGTCTCGAGACAGAGGCCATG
TTCCTCGTCGTGCGGATCCTTCACGTCCGGCAGGATCCGGACACCGGCTTCGCCTAG

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10051.22 Da        Isoelectric Point: 4.6768

>AT118012 WP_129388396.1 NZ_CP035501:c4600742-4600470 [Sphingosinicella sp. BN140058]
MPKNTSVSLSDHFDRFIAEQVKAGHYGSASEVVRDGLRLLEERQIRMQALRAELQAGLDSGIAEEFDIDEWLAEKTSETP
RPRSPQAVPA

Download         Length: 273 bp

>AT118012 NZ_CP035501:c4600742-4600470 [Sphingosinicella sp. BN140058]
ATGCCGAAGAACACGTCGGTAAGCCTCAGCGATCACTTTGATCGCTTCATTGCGGAACAGGTGAAGGCGGGTCACTACGG
TTCAGCGAGCGAGGTCGTCCGCGACGGCCTCCGATTGTTGGAGGAGCGTCAGATCCGCATGCAGGCGCTGAGGGCTGAGC
TCCAGGCCGGCTTGGACAGTGGAATCGCGGAAGAGTTCGACATCGACGAGTGGCTTGCGGAGAAGACCAGCGAGACCCCC
AGACCAAGATCGCCTCAGGCTGTACCAGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References