Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 1316610..1317217 Replicon chromosome
Accession NZ_CP035495
Organism Xylanimonas allomyrinae strain 2JSPR-7

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag ET495_RS05980 Protein ID WP_129203419.1
Coordinates 1316610..1316963 (-) Length 118 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag ET495_RS05985 Protein ID WP_129203421.1
Coordinates 1316960..1317217 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ET495_RS05955 1313389..1314108 + 720 WP_162616377.1 hypothetical protein -
ET495_RS05960 1314119..1314748 + 630 WP_129203412.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
ET495_RS05965 1314771..1315013 - 243 Protein_1178 transposase -
ET495_RS05970 1315066..1315473 + 408 WP_211340962.1 hypothetical protein -
ET495_RS05975 1315925..1316599 + 675 WP_129203417.1 DDE-type integrase/transposase/recombinase -
ET495_RS05980 1316610..1316963 - 354 WP_129203419.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
ET495_RS05985 1316960..1317217 - 258 WP_129203421.1 antitoxin Antitoxin
ET495_RS05995 1317474..1317865 + 392 Protein_1183 VOC family protein -
ET495_RS06000 1317899..1318705 - 807 WP_162616378.1 MerR family transcriptional regulator -
ET495_RS06005 1319161..1319697 - 537 WP_129203426.1 HipA N-terminal domain-containing protein -
ET495_RS06010 1319690..1319941 - 252 WP_129203428.1 helix-turn-helix domain-containing protein -
ET495_RS06015 1320549..1321322 - 774 WP_129203430.1 ABC transporter permease -
ET495_RS06020 1321319..1322122 - 804 WP_129203432.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 1308410..1326312 17902


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-116)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 118 a.a.        Molecular weight: 12468.10 Da        Isoelectric Point: 7.3618

>T117983 WP_129203419.1 NZ_CP035495:c1316963-1316610 [Xylanimonas allomyrinae]
VRRGEVWAVELDPARGSEASKTRRCVIVSRDASNKAVETHGRGVITVVPLTSSVARVLPFQALIPAEPGNGLDHDSKAQA
EQVRSVDVSRLVARVGTLRSEHVGAVDDALITHLGLD

Download         Length: 354 bp

>T117983 NZ_CP035495:c1316963-1316610 [Xylanimonas allomyrinae]
GTGAGGCGTGGCGAGGTCTGGGCGGTCGAGCTTGACCCTGCGCGAGGCTCGGAGGCATCCAAGACAAGGCGGTGCGTGAT
CGTCTCGCGCGACGCGAGCAACAAGGCCGTCGAGACGCACGGGAGGGGCGTCATCACGGTGGTTCCGTTGACGTCGTCCG
TTGCTCGAGTTCTTCCCTTCCAGGCGCTGATCCCTGCGGAGCCGGGGAATGGACTCGACCACGACTCGAAGGCTCAGGCC
GAACAGGTCCGCTCCGTGGATGTGTCGCGGCTGGTGGCCCGCGTCGGGACGCTTCGCTCCGAGCATGTGGGTGCGGTGGA
CGACGCGCTGATCACTCACCTGGGCCTGGACTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9361.41 Da        Isoelectric Point: 4.8428

>AT117983 WP_129203421.1 NZ_CP035495:c1317217-1316960 [Xylanimonas allomyrinae]
MTAGAMGRETVKLSASLPAADVAYLERYARRHRLPSRSATLHAAVQALRERELETQYAEAYREWEESGEAAIWDATAADG
IEPVA

Download         Length: 258 bp

>AT117983 NZ_CP035495:c1317217-1316960 [Xylanimonas allomyrinae]
ATGACCGCTGGTGCGATGGGTCGGGAGACCGTCAAGCTCAGTGCGAGCCTGCCGGCCGCAGACGTGGCGTACCTGGAGCG
CTACGCAAGGCGCCACCGACTGCCGTCGCGATCGGCCACACTGCACGCCGCGGTACAGGCCCTTCGCGAACGCGAGCTCG
AAACGCAGTACGCGGAGGCGTATCGCGAGTGGGAGGAGTCCGGAGAGGCGGCGATCTGGGACGCGACTGCTGCCGACGGG
ATCGAGCCGGTCGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References