Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vapBC/PIN-StbC |
Location | 1739577..1740205 | Replicon | chromosome |
Accession | NZ_CP035494 | ||
Organism | Microbacterium protaetiae strain DFW100M-13 |
Toxin (Protein)
Gene name | vapC | Uniprot ID | - |
Locus tag | ET475_RS08050 | Protein ID | WP_129388356.1 |
Coordinates | 1739577..1739981 (-) | Length | 135 a.a. |
Antitoxin (Protein)
Gene name | vapB | Uniprot ID | - |
Locus tag | ET475_RS08055 | Protein ID | WP_129388359.1 |
Coordinates | 1739978..1740205 (-) | Length | 76 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
ET475_RS08025 | 1735173..1736432 | - | 1260 | WP_129388341.1 | aminotransferase class V-fold PLP-dependent enzyme | - |
ET475_RS08030 | 1736422..1737393 | - | 972 | WP_129388344.1 | hypothetical protein | - |
ET475_RS08035 | 1737395..1738255 | - | 861 | WP_129388347.1 | tryptophan 2,3-dioxygenase | - |
ET475_RS08040 | 1738385..1738708 | - | 324 | WP_129388350.1 | HEPN domain-containing protein | - |
ET475_RS08045 | 1738853..1739446 | - | 594 | WP_129388353.1 | winged helix-turn-helix domain-containing protein | - |
ET475_RS08050 | 1739577..1739981 | - | 405 | WP_129388356.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
ET475_RS08055 | 1739978..1740205 | - | 228 | WP_129388359.1 | toxin-antitoxin system, antitoxin component | Antitoxin |
ET475_RS08060 | 1740396..1741904 | - | 1509 | WP_129388362.1 | HNH endonuclease | - |
ET475_RS08065 | 1742421..1742675 | - | 255 | WP_129388365.1 | NrdH-redoxin | - |
ET475_RS08070 | 1742672..1743388 | - | 717 | WP_207205440.1 | TetR/AcrR family transcriptional regulator C-terminal domain-containing protein | - |
ET475_RS08075 | 1743454..1744398 | + | 945 | WP_129388370.1 | zinc-binding alcohol dehydrogenase family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 135 a.a. Molecular weight: 13917.06 Da Isoelectric Point: 5.5424
>T117978 WP_129388356.1 NZ_CP035494:c1739981-1739577 [Microbacterium protaetiae]
MIVLDASAAVEWLLGRSGARFVAERIADPDVSIHAPAPIGVEVVSALRGLTLRHHMSADRGAAAIADLAAAGVDLHDPTP
LLPRAWQLRANLSAYDAVYVALAEVLDATLLTTDARIARAPGIAAEVVVVPTGK
MIVLDASAAVEWLLGRSGARFVAERIADPDVSIHAPAPIGVEVVSALRGLTLRHHMSADRGAAAIADLAAAGVDLHDPTP
LLPRAWQLRANLSAYDAVYVALAEVLDATLLTTDARIARAPGIAAEVVVVPTGK
Download Length: 405 bp
>T117978 NZ_CP035494:c1739981-1739577 [Microbacterium protaetiae]
ATGATCGTGCTGGATGCCTCGGCAGCAGTCGAGTGGCTGTTGGGCCGGAGTGGCGCCCGGTTCGTCGCCGAACGCATCGC
GGATCCAGATGTCTCGATCCATGCGCCCGCCCCGATCGGTGTCGAGGTGGTGTCTGCCCTGCGCGGACTCACGCTCAGGC
ACCACATGAGCGCAGATCGTGGTGCCGCCGCGATCGCCGACCTGGCTGCCGCCGGCGTCGACCTGCACGACCCCACCCCA
TTGCTTCCCCGCGCCTGGCAACTGCGCGCCAATCTGTCGGCGTACGACGCCGTGTACGTGGCACTCGCCGAGGTACTGGA
TGCCACTCTTCTCACGACGGACGCCCGCATCGCGCGGGCACCAGGCATCGCGGCCGAGGTCGTGGTCGTGCCGACGGGCA
AGTGA
ATGATCGTGCTGGATGCCTCGGCAGCAGTCGAGTGGCTGTTGGGCCGGAGTGGCGCCCGGTTCGTCGCCGAACGCATCGC
GGATCCAGATGTCTCGATCCATGCGCCCGCCCCGATCGGTGTCGAGGTGGTGTCTGCCCTGCGCGGACTCACGCTCAGGC
ACCACATGAGCGCAGATCGTGGTGCCGCCGCGATCGCCGACCTGGCTGCCGCCGGCGTCGACCTGCACGACCCCACCCCA
TTGCTTCCCCGCGCCTGGCAACTGCGCGCCAATCTGTCGGCGTACGACGCCGTGTACGTGGCACTCGCCGAGGTACTGGA
TGCCACTCTTCTCACGACGGACGCCCGCATCGCGCGGGCACCAGGCATCGCGGCCGAGGTCGTGGTCGTGCCGACGGGCA
AGTGA
Antitoxin
Download Length: 76 a.a. Molecular weight: 8286.50 Da Isoelectric Point: 9.1275
>AT117978 WP_129388359.1 NZ_CP035494:c1740205-1739978 [Microbacterium protaetiae]
MTMIQIRNVPDEVHRRLKARAAMEGVSLSELALAELRRSLDRPTRAELIDLVASRESVSDGPSSVELVTAARSTR
MTMIQIRNVPDEVHRRLKARAAMEGVSLSELALAELRRSLDRPTRAELIDLVASRESVSDGPSSVELVTAARSTR
Download Length: 228 bp
>AT117978 NZ_CP035494:c1740205-1739978 [Microbacterium protaetiae]
ATGACAATGATCCAGATTCGCAACGTGCCCGATGAGGTGCACCGACGCCTCAAGGCGCGCGCAGCGATGGAGGGCGTGTC
ACTGTCAGAGCTCGCTTTGGCCGAGCTTCGGCGCTCCCTCGATCGGCCCACGCGCGCAGAGTTGATCGATCTCGTCGCGT
CTCGCGAGTCCGTCTCCGATGGTCCTTCTTCGGTCGAACTGGTGACCGCGGCGCGCTCGACACGATGA
ATGACAATGATCCAGATTCGCAACGTGCCCGATGAGGTGCACCGACGCCTCAAGGCGCGCGCAGCGATGGAGGGCGTGTC
ACTGTCAGAGCTCGCTTTGGCCGAGCTTCGGCGCTCCCTCGATCGGCCCACGCGCGCAGAGTTGATCGATCTCGTCGCGT
CTCGCGAGTCCGTCTCCGATGGTCCTTCTTCGGTCGAACTGGTGACCGCGGCGCGCTCGACACGATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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