Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 1352299..1352930 Replicon chromosome
Accession NZ_CP035493
Organism Xylanimicrobium sp. FW10M-9

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag ET471_RS06100 Protein ID WP_129187057.1
Coordinates 1352299..1352703 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag ET471_RS06105 Protein ID WP_129187058.1
Coordinates 1352700..1352930 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ET471_RS06090 1349810..1351594 + 1785 WP_129187055.1 ribonucleoside triphosphate reductase -
ET471_RS06095 1351575..1352297 + 723 WP_129187056.1 anaerobic ribonucleoside-triphosphate reductase activating protein -
ET471_RS06100 1352299..1352703 - 405 WP_129187057.1 type II toxin-antitoxin system VapC family toxin Toxin
ET471_RS06105 1352700..1352930 - 231 WP_129187058.1 antitoxin Antitoxin
ET471_RS06110 1352971..1353717 - 747 WP_129187059.1 aquaporin family protein -
ET471_RS06115 1353766..1354632 - 867 WP_129187060.1 SDR family NAD(P)-dependent oxidoreductase -
ET471_RS06120 1354629..1355165 - 537 WP_129187061.1 PH domain-containing protein -
ET471_RS06125 1355197..1355835 - 639 WP_129187062.1 histidine phosphatase family protein -
ET471_RS06130 1356242..1357900 + 1659 WP_129187063.1 Rv2578c family radical SAM protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-125)

Antitoxin

SpoVT-AbrB domain

(7-48)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14395.34 Da        Isoelectric Point: 4.9036

>T117975 WP_129187057.1 NZ_CP035493:c1352703-1352299 [Xylanimicrobium sp. FW10M-9]
VTTLYLLDTNILIDLLRGRGALARPRLEAAEGRVGVSTISTMELDYGVERSSDPARSRQALDGLLSLMDEIPFDAHAALH
SGRIRAHLAAAGTPIGPYDVLIAGHARSLGTVLVTHDVDEFSRVPGLEVEDWLA

Download         Length: 405 bp

>T117975 NZ_CP035493:c1352703-1352299 [Xylanimicrobium sp. FW10M-9]
GTGACGACGCTCTACCTCCTGGACACGAACATCCTCATCGATCTCCTGCGCGGGCGTGGAGCCCTCGCGCGCCCGCGCCT
CGAGGCCGCCGAGGGCCGCGTCGGCGTGTCGACCATCAGCACCATGGAGCTGGACTACGGCGTCGAGCGCTCGTCCGACC
CGGCTCGGAGCCGCCAGGCCCTCGACGGGCTCCTGTCCCTCATGGACGAGATCCCGTTCGACGCCCACGCCGCCCTGCAC
AGCGGCCGGATCCGCGCGCACCTCGCCGCCGCCGGCACGCCGATCGGACCGTACGACGTCCTGATCGCCGGGCACGCCCG
GTCGCTCGGAACCGTGCTCGTCACGCACGACGTCGACGAGTTCTCCCGGGTCCCCGGCCTGGAGGTCGAGGACTGGCTCG
CGTAG

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8521.62 Da        Isoelectric Point: 7.0111

>AT117975 WP_129187058.1 NZ_CP035493:c1352930-1352700 [Xylanimicrobium sp. FW10M-9]
MSTTRLFRSNTTQAVRLPKPVAFPETVRDVEIRVVGQSRVITPVGSSWADWFDHGLVVPDFPAEREQGVAPERGSW

Download         Length: 231 bp

>AT117975 NZ_CP035493:c1352930-1352700 [Xylanimicrobium sp. FW10M-9]
ATGTCGACCACGCGACTGTTCCGCAGCAACACCACCCAGGCTGTCCGCCTGCCCAAGCCCGTCGCCTTCCCCGAGACGGT
GCGCGACGTCGAGATCCGCGTCGTCGGGCAGTCCCGTGTGATCACCCCCGTCGGCTCGTCCTGGGCCGACTGGTTCGACC
ACGGGCTCGTGGTCCCCGACTTCCCGGCCGAGCGGGAGCAGGGCGTCGCCCCGGAGCGCGGGTCCTGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References