Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 3933335..3935046 Replicon chromosome
Accession NZ_CP035490
Organism Hahella sp. KA22

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag EUZ85_RS17600 Protein ID WP_127970514.1
Coordinates 3933335..3933979 (+) Length 215 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag EUZ85_RS17605 Protein ID WP_127970515.1
Coordinates 3933979..3935046 (+) Length 356 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EUZ85_RS17580 3928350..3929360 + 1011 WP_206618099.1 substrate-binding domain-containing protein -
EUZ85_RS17585 3929427..3930911 - 1485 WP_127970512.1 ricin-type beta-trefoil lectin domain protein -
EUZ85_RS17590 3931451..3932242 + 792 WP_127974507.1 DUF429 domain-containing protein -
EUZ85_RS17595 3932731..3933330 + 600 WP_127970513.1 DUF4433 domain-containing protein -
EUZ85_RS17600 3933335..3933979 + 645 WP_127970514.1 DUF4433 domain-containing protein Toxin
EUZ85_RS17605 3933979..3935046 + 1068 WP_127970515.1 macro domain-containing protein Antitoxin
EUZ85_RS17610 3935089..3936906 - 1818 WP_164887278.1 tetratricopeptide repeat protein -
EUZ85_RS17615 3937025..3938056 - 1032 WP_127970517.1 VWA domain-containing protein -
EUZ85_RS17620 3938569..3939102 - 534 WP_127970518.1 hypothetical protein -
EUZ85_RS17625 3939324..3939758 + 435 WP_127970519.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(14-214)

Antitoxin

Macro domain

(18-130)


Sequences

Toxin        


Download         Length: 215 a.a.        Molecular weight: 24902.36 Da        Isoelectric Point: 6.9658

>T117971 WP_127970514.1 NZ_CP035490:3933335-3933979 [Hahella sp. KA22]
MIYTSLNPQKALIWRIVHRENVPWILDHGLHCGNSPVSSSNWVSIGNPELTDKRATHAVPVGPKGYLNDYVPFYFTPFSP
MMKNIHSGWGGIKQRPNEEIVILVSDLYRVSEMGLPFVFTNGHAYYAWTDFFTDLDDLENIDWTIIQSRDFKRDPNDPAK
FERYQAEALIHQSCPVDALKGMVCYTENTKKRLDGWLHERQMAMPVHARPRWYF

Download         Length: 645 bp

>T117971 NZ_CP035490:3933335-3933979 [Hahella sp. KA22]
ATGATCTATACCAGTTTGAACCCACAGAAAGCGCTCATCTGGCGCATTGTTCATCGTGAAAATGTTCCTTGGATTCTAGA
CCACGGTTTGCACTGTGGAAACAGTCCAGTTAGCTCGTCTAATTGGGTGAGTATTGGTAATCCTGAGTTAACTGACAAAC
GCGCGACGCATGCAGTTCCCGTGGGGCCAAAAGGATACTTGAATGACTATGTGCCTTTCTATTTCACTCCGTTCTCCCCA
ATGATGAAAAATATTCACAGCGGATGGGGAGGAATTAAACAGCGGCCGAATGAGGAGATTGTAATTCTCGTTTCCGACTT
GTACCGTGTCAGCGAAATGGGGCTACCCTTTGTTTTTACCAATGGGCATGCATATTACGCTTGGACCGACTTCTTCACTG
ACCTAGACGACCTAGAAAATATTGATTGGACTATTATCCAGTCCAGAGATTTCAAGCGAGACCCTAATGACCCAGCCAAA
TTCGAGCGATATCAGGCTGAGGCACTGATACATCAATCTTGTCCAGTCGATGCCTTAAAGGGCATGGTTTGTTACACTGA
AAACACAAAAAAACGATTGGATGGTTGGTTGCACGAGCGACAAATGGCCATGCCAGTTCATGCGCGGCCAAGGTGGTATT
TCTAA

Antitoxin


Download         Length: 356 a.a.        Molecular weight: 40215.21 Da        Isoelectric Point: 6.2639

>AT117971 WP_127970515.1 NZ_CP035490:3933979-3935046 [Hahella sp. KA22]
MISYAQGNLLEAEVEALVNTVNTVGVMGKGIALMFKERFPQNMQAYVRACRTGDVVTGKMFITKTDELMGPKWIVNFPTK
QHWRAKSKMEWIDEGLVDLRRFITEHHVKSIAIPPLGAGNGGLSWQDVKRRIEKALTDIEGVDIRVYEPTAKYQNVSKKA
GVSELTTSRAMVAELVRRYWILGMECSLLEIQKLAWFLQRVIDAQGLKNDLELHFEANYYGPYANNLTHLLNALDGSYLK
SDKRIPDSDPLDVIAFNDTKREYVETYLNTEGQDYLPALEKASEIISGFESPFGMELLATVDWLLTREGCEPTLESIKGG
IAHWPSGKKWAERKLALFDDRSLQFAIDRMKTASI

Download         Length: 1068 bp

>AT117971 NZ_CP035490:3933979-3935046 [Hahella sp. KA22]
ATGATTTCGTATGCACAAGGTAATTTACTTGAGGCGGAAGTGGAAGCGCTGGTGAATACCGTAAATACCGTTGGAGTGAT
GGGAAAGGGCATTGCTCTGATGTTTAAAGAGCGCTTTCCGCAAAATATGCAGGCTTATGTCAGGGCCTGTAGAACAGGAG
ATGTGGTCACAGGGAAGATGTTCATCACTAAAACAGACGAGCTGATGGGGCCGAAGTGGATTGTTAATTTCCCAACGAAG
CAGCATTGGCGCGCAAAGTCCAAAATGGAGTGGATTGATGAGGGGCTTGTGGATTTGCGTCGATTTATTACAGAACACCA
TGTAAAGTCAATTGCAATCCCCCCGTTAGGTGCCGGTAATGGTGGTTTAAGCTGGCAGGACGTGAAGCGCCGCATTGAAA
AAGCCCTTACTGATATTGAGGGCGTCGATATTCGGGTTTATGAACCCACAGCAAAATATCAAAACGTTTCAAAAAAGGCG
GGTGTAAGCGAGCTTACCACTTCACGAGCAATGGTCGCTGAACTTGTGCGTCGCTATTGGATACTCGGTATGGAGTGCAG
CTTACTCGAAATTCAAAAGCTTGCTTGGTTTTTACAGCGAGTAATTGATGCGCAAGGTTTAAAAAATGACTTGGAGCTTC
ATTTTGAAGCCAATTACTACGGGCCTTACGCTAATAACTTAACTCATTTATTGAATGCTCTAGATGGTAGCTACCTTAAG
TCTGATAAGCGCATTCCTGACAGTGACCCTCTGGACGTCATCGCTTTTAACGATACCAAAAGAGAATACGTTGAAACTTA
TTTGAATACTGAGGGGCAGGATTATTTGCCTGCATTAGAAAAAGCCAGCGAGATAATTAGTGGCTTTGAATCGCCCTTTG
GGATGGAGTTGCTTGCCACTGTTGACTGGTTGCTAACAAGAGAAGGGTGCGAACCTACTTTGGAGTCCATTAAGGGCGGT
ATTGCTCATTGGCCATCAGGAAAGAAATGGGCTGAGCGCAAGCTTGCTTTATTTGATGACAGAAGCTTGCAATTCGCAAT
AGATCGAATGAAGACGGCTTCAATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References