Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 1013920..1014580 Replicon chromosome
Accession NZ_CP035382
Organism Leclercia adecarboxylata strain R25

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag ES815_RS05735 Protein ID WP_142487009.1
Coordinates 1013920..1014333 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag ES815_RS05740 Protein ID WP_142487010.1
Coordinates 1014314..1014580 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ES815_RS05715 1009923..1011656 - 1734 WP_142487005.1 single-stranded-DNA-specific exonuclease RecJ -
ES815_RS05720 1011662..1012375 - 714 WP_142487006.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
ES815_RS05725 1012397..1013293 - 897 WP_142487007.1 site-specific tyrosine recombinase XerD -
ES815_RS05730 1013395..1013916 + 522 WP_142487008.1 flavodoxin FldB -
ES815_RS05735 1013920..1014333 - 414 WP_142487009.1 protein YgfX Toxin
ES815_RS05740 1014314..1014580 - 267 WP_142487010.1 FAD assembly factor SdhE Antitoxin
ES815_RS05745 1014886..1015866 + 981 WP_142487011.1 tRNA-modifying protein YgfZ -
ES815_RS05750 1015961..1016620 - 660 WP_142487012.1 hemolysin III family protein -
ES815_RS05755 1016786..1017097 - 312 WP_142487013.1 N(4)-acetylcytidine aminohydrolase -
ES815_RS05760 1017149..1017880 + 732 WP_142490021.1 MurR/RpiR family transcriptional regulator -
ES815_RS05765 1017994..1019427 + 1434 WP_142487014.1 6-phospho-beta-glucosidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16203.99 Da        Isoelectric Point: 10.6531

>T117676 WP_142487009.1 NZ_CP035382:c1014333-1013920 [Leclercia adecarboxylata]
VVLWQSDLRVSWRAQWMSLLLHGLVAACILLMPWPLSYTPLWLILLSLVVFDSVRSQRRINSRQGEIKLFMDSRLHWQGS
EWEIVGTPWMLNAGMMLRLRKGDGKRYQHLWLAADSMDEGEWRDLRRMLSQQPTQGR

Download         Length: 414 bp

>T117676 NZ_CP035382:c1014333-1013920 [Leclercia adecarboxylata]
GTGGTCCTGTGGCAATCTGATTTACGCGTCTCGTGGCGCGCCCAGTGGATGTCTCTTTTGCTCCACGGCCTGGTTGCGGC
TTGCATTCTGTTGATGCCATGGCCGCTGAGCTACACCCCATTATGGTTAATCTTACTGTCGCTGGTGGTGTTCGACAGCG
TGCGCAGTCAACGACGCATTAATTCCCGTCAGGGCGAAATCAAACTGTTCATGGATTCCCGACTGCACTGGCAGGGCAGC
GAGTGGGAGATTGTCGGCACGCCGTGGATGCTAAATGCCGGCATGATGCTTCGCTTACGCAAAGGCGACGGGAAACGCTA
CCAGCATTTGTGGCTGGCGGCAGACAGCATGGACGAAGGGGAGTGGCGGGATCTGCGCCGGATGCTGTCGCAGCAACCGA
CGCAGGGGCGATAG

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10539.02 Da        Isoelectric Point: 4.5242

>AT117676 WP_142487010.1 NZ_CP035382:c1014580-1014314 [Leclercia adecarboxylata]
MDITNKARIHWACRRGMRELDISIMPFFEYEYDTLSDEDKQLFIRLLENDDPDLFNWLMNHGEPADAELQRMVLLIQTRN
RERGPVAI

Download         Length: 267 bp

>AT117676 NZ_CP035382:c1014580-1014314 [Leclercia adecarboxylata]
ATGGACATTACTAACAAAGCCCGCATTCATTGGGCATGCCGTCGCGGCATGCGCGAACTCGATATCTCCATCATGCCGTT
CTTCGAATACGAATACGACACCCTGAGCGATGAGGACAAACAGCTCTTCATCCGTCTGCTGGAGAACGACGATCCTGATT
TATTTAACTGGTTGATGAATCACGGCGAACCTGCCGACGCCGAACTGCAACGGATGGTGCTTTTAATTCAAACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References