Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2467048..2467319 Replicon chromosome
Accession NZ_CP035366
Organism Escherichia coli O157:H7 strain C1-057

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2467086..2467189 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2467048..2467319 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ES669_RS12770 2464205..2465644 + 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
ES669_RS12775 2465762..2465998 + 237 WP_001295499.1 DUF1480 family protein -
ES669_RS12780 2466103..2466294 + 192 WP_001296140.1 YebW family protein -
ES669_RS12785 2466295..2466951 - 657 WP_000812736.1 protein-serine/threonine phosphatase -
- 2467048..2467319 + 272 - - Antitoxin
- 2467086..2467189 - 104 - - Toxin
ES669_RS12790 2467347..2467688 - 342 WP_000976483.1 YebY family protein -
ES669_RS12795 2467701..2468573 - 873 WP_000879314.1 copper homeostasis membrane protein CopD -
ES669_RS12800 2468577..2468951 - 375 WP_000168751.1 CopC domain-containing protein YobA -
ES669_RS12805 2469090..2469320 + 231 WP_000916763.1 DNA polymerase III subunit theta -
ES669_RS12810 2469422..2470078 + 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
ES669_RS12815 2470102..2470764 + 663 WP_000944243.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T117630 NZ_CP035366:c2467189-2467086 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT117630 NZ_CP035366:2467048-2467319 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References