Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicA-HicB
Location 2799860..2800461 Replicon chromosome
Accession NZ_CP035300
Organism Dyella sp. M7H15-1

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag EO087_RS12965 Protein ID WP_128899947.1
Coordinates 2800279..2800461 (-) Length 61 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag EO087_RS12960 Protein ID WP_128899228.1
Coordinates 2799860..2800270 (-) Length 137 a.a.

Genomic Context

EO087_RS12945EO087_RS12950EO087_RS12955EO087_RS12960EO087_RS12965EO087_RS12970EO087_RS12975EO087_RS12980EO087_RS12985EO087_RS12990
Location: 2796819..2797451 (633 bp)
Type: Others
Protein ID: WP_128899226.1
Location: 2797587..2798729 (1143 bp)
Type: Others
Protein ID: WP_128899227.1
Location: 2798748..2799851 (1104 bp)
Type: Others
Protein ID: WP_128899946.1
Location: 2799860..2800270 (411 bp)
Type: Antitoxin
Protein ID: WP_128899228.1
Location: 2800279..2800461 (183 bp)
Type: Toxin
Protein ID: WP_128899947.1
Location: 2800693..2801349 (657 bp)
Type: Others
Protein ID: WP_205744365.1
Location: 2801521..2802177 (657 bp)
Type: Others
Protein ID: WP_205744366.1
Location: 2802862..2803335 (474 bp)
Type: Others
Protein ID: WP_164931839.1
Location: 2803427..2803957 (531 bp)
Type: Others
Protein ID: WP_128899232.1
Location: 2804070..2804600 (531 bp)
Type: Others
Protein ID: WP_128899233.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
EO087_RS129452796819..2797451+633WP_128899226.1isopentenyl-diphosphate Delta-isomerase-
EO087_RS129502797587..2798729+1143WP_128899227.1adenosyl-hopene transferase HpnH-
EO087_RS129552798748..2799851+1104WP_128899946.1glycosyltransferase-
EO087_RS129602799860..2800270-411WP_128899228.1type II toxin-antitoxin system HicB family antitoxinAntitoxin
EO087_RS129652800279..2800461-183WP_128899947.1type II toxin-antitoxin system HicA family toxinToxin
EO087_RS129702800693..2801349-657WP_205744365.1fimbria/pilus periplasmic chaperone-
EO087_RS129752801521..2802177-657WP_205744366.1fimbria/pilus periplasmic chaperone-
EO087_RS129802802862..2803335-474WP_164931839.1type 1 fimbrial protein-
EO087_RS129852803427..2803957-531WP_128899232.1type 1 fimbrial protein-
EO087_RS129902804070..2804600-531WP_128899233.1fimbrial protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(4-59)

Antitoxin

HicB-like antitoxin of toxin-antitoxin system

(3-127)


Sequences

Toxin        


Download         Length: 61 a.a.        Molecular weight: 6650.76 Da        Isoelectric Point: 11.0850

>T117573 WP_128899947.1 NZ_CP035300:c2800461-2800279 [Dyella sp. M7H15-1]
IKSADVIKRLEAEGWMLSRIKGSHHQFKHPAKPGLVTVPHPKADTPKGTFHSIAKQAGWK

Download         Length: 183 bp

>T117573 NZ_CP035300:c2800461-2800279 [Dyella sp. M7H15-1]
ATAAAGAGCGCGGATGTGATCAAGCGGCTGGAAGCCGAGGGCTGGATGCTTAGCCGAATCAAGGGTTCACATCACCAGTT
CAAACATCCAGCAAAGCCCGGCCTTGTAACTGTCCCGCACCCCAAAGCCGATACTCCGAAAGGTACTTTCCATAGCATCG
CCAAGCAGGCGGGATGGAAATAG

Antitoxin


Download         Length: 137 a.a.        Molecular weight: 14919.91 Da        Isoelectric Point: 4.6143

>AT117573 WP_128899228.1 NZ_CP035300:c2800270-2799860 [Dyella sp. M7H15-1]
MRFPVVLHTDDGLHYGVIVPDLPGCYSAGDSIDDALVQVLEAIDLHLEGMMEDDKTELPEPSLINAHQQNPDYVGGIWAV
VDFDTSKYEGKAEKINITVPRKLLSKIDAYVSNHPGETRSGFMTRAALQVIRGKAA

Download         Length: 411 bp

>AT117573 NZ_CP035300:c2800270-2799860 [Dyella sp. M7H15-1]
ATGCGATTCCCAGTTGTTCTCCATACGGATGACGGCCTGCACTACGGCGTCATCGTCCCGGATTTGCCTGGCTGTTATTC
GGCAGGCGATTCTATTGATGACGCCCTCGTGCAAGTACTTGAGGCCATCGACCTGCATCTGGAGGGCATGATGGAAGACG
ACAAGACCGAGCTACCGGAACCCAGCCTGATCAATGCGCACCAGCAGAATCCGGATTACGTCGGTGGCATATGGGCCGTG
GTCGACTTCGATACGTCCAAGTACGAAGGCAAGGCGGAAAAAATCAACATTACCGTGCCACGTAAGTTGCTTTCGAAGAT
CGATGCCTATGTGTCCAATCATCCAGGAGAGACACGATCTGGCTTTATGACTCGTGCCGCCCTGCAAGTGATACGCGGCA
AAGCTGCGTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References