Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/VapC-VagC |
| Location | 2477575..2478275 | Replicon | chromosome |
| Accession | NZ_CP035300 | ||
| Organism | Dyella sp. M7H15-1 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | EO087_RS11490 | Protein ID | WP_205744489.1 |
| Coordinates | 2477883..2478275 (+) | Length | 131 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | EO087_RS11485 | Protein ID | WP_205744488.1 |
| Coordinates | 2477575..2477874 (+) | Length | 100 a.a. |
Genomic Context
Location: 2473519..2475351 (1833 bp)
Type: Others
Protein ID: WP_205744487.1
Type: Others
Protein ID: WP_205744487.1
Location: 2475696..2476382 (687 bp)
Type: Others
Protein ID: WP_128898979.1
Type: Others
Protein ID: WP_128898979.1
Location: 2477254..2477514 (261 bp)
Type: Others
Protein ID: WP_128898981.1
Type: Others
Protein ID: WP_128898981.1
Location: 2477575..2477874 (300 bp)
Type: Antitoxin
Protein ID: WP_205744488.1
Type: Antitoxin
Protein ID: WP_205744488.1
Location: 2477883..2478275 (393 bp)
Type: Toxin
Protein ID: WP_205744489.1
Type: Toxin
Protein ID: WP_205744489.1
Location: 2475358..2475531 (174 bp)
Type: Others
Protein ID: WP_164931826.1
Type: Others
Protein ID: WP_164931826.1
Location: 2476436..2476759 (324 bp)
Type: Others
Protein ID: WP_128898980.1
Type: Others
Protein ID: WP_128898980.1
Location: 2476798..2477118 (321 bp)
Type: Others
Protein ID: WP_128899921.1
Type: Others
Protein ID: WP_128899921.1
Location: 2478326..2478601 (276 bp)
Type: Others
Protein ID: WP_128898984.1
Type: Others
Protein ID: WP_128898984.1
Location: 2478718..2480073 (1356 bp)
Type: Others
Protein ID: WP_128898985.1
Type: Others
Protein ID: WP_128898985.1
Location: 2480462..2481841 (1380 bp)
Type: Others
Protein ID: WP_128898986.1
Type: Others
Protein ID: WP_128898986.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EO087_RS11460 | 2473519..2475351 | + | 1833 | WP_205744487.1 | KUP/HAK/KT family potassium transporter | - |
| EO087_RS16270 | 2475358..2475531 | - | 174 | WP_164931826.1 | hypothetical protein | - |
| EO087_RS11465 | 2475696..2476382 | + | 687 | WP_128898979.1 | aspartyl/asparaginyl beta-hydroxylase domain-containing protein | - |
| EO087_RS11470 | 2476436..2476759 | - | 324 | WP_128898980.1 | helix-turn-helix domain-containing protein | - |
| EO087_RS11475 | 2476798..2477118 | - | 321 | WP_128899921.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| EO087_RS11480 | 2477254..2477514 | + | 261 | WP_128898981.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | - |
| EO087_RS11485 | 2477575..2477874 | + | 300 | WP_205744488.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin |
| EO087_RS11490 | 2477883..2478275 | + | 393 | WP_205744489.1 | PIN domain-containing protein | Toxin |
| EO087_RS11495 | 2478326..2478601 | - | 276 | WP_128898984.1 | hypothetical protein | - |
| EO087_RS11500 | 2478718..2480073 | - | 1356 | WP_128898985.1 | hypothetical protein | - |
| EO087_RS11505 | 2480462..2481841 | - | 1380 | WP_128898986.1 | hypothetical protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 131 a.a. Molecular weight: 14161.35 Da Isoelectric Point: 4.9107
>T117572 WP_205744489.1 NZ_CP035300:2477883-2478275 [Dyella sp. M7H15-1]
MLDTNIISDVIRSPNGLAARHIEQVGPKEIFTSIIVAAELRYGCAKKGSPKLLTKVEGILETIPVLPLDIPADAEYGGIR
AELEAAGQPIGMNDLLIAAHTYALGLTLVTDNTREFNRIRGLNVENWLER
MLDTNIISDVIRSPNGLAARHIEQVGPKEIFTSIIVAAELRYGCAKKGSPKLLTKVEGILETIPVLPLDIPADAEYGGIR
AELEAAGQPIGMNDLLIAAHTYALGLTLVTDNTREFNRIRGLNVENWLER
Download Length: 393 bp
>T117572 NZ_CP035300:2477883-2478275 [Dyella sp. M7H15-1]
CTGCTGGACACGAACATCATCAGCGATGTGATCCGCAGCCCGAATGGACTTGCTGCACGCCACATTGAGCAGGTCGGACC
GAAGGAGATTTTCACCAGCATCATTGTCGCAGCCGAACTGCGCTATGGCTGCGCAAAGAAGGGCTCGCCCAAGTTGCTCA
CCAAAGTGGAGGGCATCCTTGAAACGATCCCGGTGCTACCGCTGGATATTCCGGCTGACGCTGAATATGGCGGCATCCGC
GCCGAACTGGAAGCGGCTGGCCAGCCTATCGGCATGAACGACCTGCTGATCGCCGCACACACCTATGCGCTTGGCCTCAC
GCTAGTAACGGACAACACGCGCGAATTCAACCGCATCCGTGGCCTCAACGTAGAGAACTGGCTGGAAAGATAG
CTGCTGGACACGAACATCATCAGCGATGTGATCCGCAGCCCGAATGGACTTGCTGCACGCCACATTGAGCAGGTCGGACC
GAAGGAGATTTTCACCAGCATCATTGTCGCAGCCGAACTGCGCTATGGCTGCGCAAAGAAGGGCTCGCCCAAGTTGCTCA
CCAAAGTGGAGGGCATCCTTGAAACGATCCCGGTGCTACCGCTGGATATTCCGGCTGACGCTGAATATGGCGGCATCCGC
GCCGAACTGGAAGCGGCTGGCCAGCCTATCGGCATGAACGACCTGCTGATCGCCGCACACACCTATGCGCTTGGCCTCAC
GCTAGTAACGGACAACACGCGCGAATTCAACCGCATCCGTGGCCTCAACGTAGAGAACTGGCTGGAAAGATAG
Antitoxin
Download Length: 100 a.a. Molecular weight: 11308.04 Da Isoelectric Point: 4.9062
>AT117572 WP_205744488.1 NZ_CP035300:2477575-2477874 [Dyella sp. M7H15-1]
MAYTLESNTMPILSTPSRPKEAKLFRNNRSQAVRIPVEFELPGDRVLIHREGSKLIIEPVTRPTNIIELLAEWRKEAPLG
PEDQFPAIEDMPAKPEDIF
MAYTLESNTMPILSTPSRPKEAKLFRNNRSQAVRIPVEFELPGDRVLIHREGSKLIIEPVTRPTNIIELLAEWRKEAPLG
PEDQFPAIEDMPAKPEDIF
Download Length: 300 bp
>AT117572 NZ_CP035300:2477575-2477874 [Dyella sp. M7H15-1]
ATGGCATATACATTGGAGAGCAATACCATGCCTATCTTATCGACGCCATCCAGACCCAAGGAGGCCAAGCTGTTTCGCAA
CAACCGCAGCCAGGCGGTGCGGATTCCTGTGGAGTTCGAGTTGCCGGGGGATCGTGTGCTGATCCATCGCGAAGGCAGCA
AACTCATCATCGAACCAGTGACTCGGCCAACGAACATCATCGAACTGCTGGCCGAGTGGAGGAAAGAAGCGCCGCTTGGG
CCAGAAGATCAGTTCCCGGCCATTGAGGACATGCCCGCCAAGCCAGAGGACATATTTTGA
ATGGCATATACATTGGAGAGCAATACCATGCCTATCTTATCGACGCCATCCAGACCCAAGGAGGCCAAGCTGTTTCGCAA
CAACCGCAGCCAGGCGGTGCGGATTCCTGTGGAGTTCGAGTTGCCGGGGGATCGTGTGCTGATCCATCGCGAAGGCAGCA
AACTCATCATCGAACCAGTGACTCGGCCAACGAACATCATCGAACTGCTGGCCGAGTGGAGGAAAGAAGCGCCGCTTGGG
CCAGAAGATCAGTTCCCGGCCATTGAGGACATGCCCGCCAAGCCAGAGGACATATTTTGA