Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 783259..783815 Replicon chromosome
Accession NZ_CP035300
Organism Dyella sp. M7H15-1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag EO087_RS03840 Protein ID WP_128897719.1
Coordinates 783519..783815 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag EO087_RS03835 Protein ID WP_128897718.1
Coordinates 783259..783531 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EO087_RS03805 779001..779799 + 799 Protein_745 ferritin-like domain-containing protein -
EO087_RS03810 780051..780473 + 423 WP_128897714.1 hypothetical protein -
EO087_RS03815 780812..781535 + 724 Protein_747 IS5 family transposase -
EO087_RS03820 781717..782001 + 285 WP_128897715.1 hypothetical protein -
EO087_RS03825 781998..782360 + 363 WP_128897716.1 transcriptional regulator -
EO087_RS03830 782720..783067 + 348 WP_128897717.1 hypothetical protein -
EO087_RS03835 783259..783531 + 273 WP_128897718.1 CopG family ribbon-helix-helix protein Antitoxin
EO087_RS03840 783519..783815 + 297 WP_128897719.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EO087_RS03845 784058..784996 - 939 WP_128897720.1 DNA-binding protein -
EO087_RS03850 785083..786192 + 1110 WP_128897721.1 ISAs1 family transposase -
EO087_RS03855 786201..786823 + 623 Protein_755 site-specific integrase -
EO087_RS03860 787128..788696 + 1569 WP_128897722.1 IS21 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 780812..781024 212


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-95)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-40)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 10833.54 Da        Isoelectric Point: 6.4564

>T117569 WP_128897719.1 NZ_CP035300:783519-783815 [Dyella sp. M7H15-1]
VPRVIVTEGAALGLERCRRFLAAKAPDAAKRAGQAIERQFLLLETAPDIGRPFPEMLELRELVIAFGDSGYVALYCHEPA
ADAVYVLAFRHQKEAGYF

Download         Length: 297 bp

>T117569 NZ_CP035300:783519-783815 [Dyella sp. M7H15-1]
GTGCCACGAGTAATCGTTACGGAAGGCGCTGCACTGGGATTGGAGCGATGCCGGCGCTTCCTTGCCGCCAAGGCCCCGGA
TGCCGCCAAGCGCGCCGGACAGGCGATCGAGCGGCAATTCCTGCTGCTGGAAACGGCCCCCGACATTGGCCGACCGTTCC
CTGAAATGCTGGAGCTGCGCGAGCTGGTGATCGCCTTCGGTGATTCCGGCTACGTGGCCTTGTATTGTCACGAACCGGCT
GCCGATGCCGTCTATGTCTTGGCATTCCGGCACCAGAAAGAGGCGGGCTACTTCTGA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10563.81 Da        Isoelectric Point: 6.8724

>AT117569 WP_128897718.1 NZ_CP035300:783259-783531 [Dyella sp. M7H15-1]
MATSLKIDDALKGRVQHLASQRRRSPHWIMLEAIQQYVEREEARESFKREALASWAAYRETGRHLTGQEVRAWLNTWGTE
DEKSVPECHE

Download         Length: 273 bp

>AT117569 NZ_CP035300:783259-783531 [Dyella sp. M7H15-1]
ATGGCAACATCGCTCAAGATTGACGATGCGCTGAAAGGCCGCGTCCAACACCTCGCCAGTCAGCGCCGCCGCTCGCCGCA
CTGGATCATGCTCGAAGCCATCCAGCAATACGTCGAGCGGGAAGAAGCACGCGAGAGCTTTAAGCGGGAAGCCTTGGCTT
CCTGGGCGGCCTATCGGGAAACCGGACGGCACCTGACCGGCCAGGAAGTGCGCGCCTGGTTGAACACCTGGGGCACCGAA
GACGAAAAGTCGGTGCCTGAGTGCCACGAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References