Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 436247..436839 Replicon chromosome
Accession NZ_CP035300
Organism Dyella sp. M7H15-1

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag EO087_RS02235 Protein ID WP_128897457.1
Coordinates 436546..436839 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag EO087_RS02230 Protein ID WP_128897456.1
Coordinates 436247..436531 (-) Length 95 a.a.

Genomic Context

EO087_RS16090EO087_RS02240EO087_RS02205EO087_RS02210EO087_RS02215EO087_RS02220EO087_RS02225EO087_RS02230EO087_RS02235EO087_RS02250EO087_RS02255EO087_RS02260
Location: 435994..436134 (141 bp)
Type: Others
Protein ID: WP_164931738.1
Location: 436921..437367 (447 bp)
Type: Others
Protein ID: WP_128897458.1
Location: 432266..432748 (483 bp)
Type: Others
Protein ID: WP_128897452.1
Location: 432928..433671 (744 bp)
Type: Others
Protein ID: WP_128897453.1
Location: 433759..434424 (666 bp)
Type: Others
Protein ID: WP_128897454.1
Location: 434486..435475 (990 bp)
Type: Others
Protein ID: WP_205744413.1
Location: 435502..435891 (390 bp)
Type: Others
Protein ID: WP_128897455.1
Location: 436247..436531 (285 bp)
Type: Antitoxin
Protein ID: WP_128897456.1
Location: 436546..436839 (294 bp)
Type: Toxin
Protein ID: WP_128897457.1
Location: 437364..438620 (1257 bp)
Type: Others
Protein ID: WP_205744414.1
Location: 438726..439484 (759 bp)
Type: Others
Protein ID: WP_128897459.1
Location: 439498..441066 (1569 bp)
Type: Others
Protein ID: WP_128897460.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
EO087_RS02205432266..432748-483WP_128897452.1hypothetical protein-
EO087_RS02210432928..433671-744WP_128897453.1hypothetical protein-
EO087_RS02215433759..434424-666WP_128897454.1hypothetical protein-
EO087_RS02220434486..435475-990WP_205744413.1hypothetical protein-
EO087_RS02225435502..435891-390WP_128897455.1hypothetical protein-
EO087_RS16090435994..436134+141WP_164931738.1hypothetical protein-
EO087_RS02230436247..436531-285WP_128897456.1putative addiction module antidote proteinAntitoxin
EO087_RS02235436546..436839-294WP_128897457.1type II toxin-antitoxin system RelE/ParE family toxinToxin
EO087_RS02240436921..437367+447WP_128897458.1lysozyme-
EO087_RS02250437364..438620-1257WP_205744414.1recombinase zinc beta ribbon domain-containing protein-
EO087_RS02255438726..439484-759WP_128897459.1IS21-like element helper ATPase IstB-
EO087_RS02260439498..441066-1569WP_128897460.1IS21 family transposase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideProphage--430613..45936628753
-flankIS/Tn--438726..439484758


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-95)

Antitoxin

Uncharacterized protein HI1420

(3-91)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11088.68 Da        Isoelectric Point: 10.3911

>T117568 WP_128897457.1 NZ_CP035300:c436839-436546 [Dyella sp. M7H15-1]
MNTIHQTEEFKAWMRDLRDDTAKAKVITRTKQAAAGNFGDVKHFDGISEMRINYGSGYRVYYAKQGKTVYLLLIGGDKSS
QDRDIKKAQKLWKSIKG

Download         Length: 294 bp

>T117568 NZ_CP035300:c436839-436546 [Dyella sp. M7H15-1]
ATGAACACGATCCACCAAACTGAAGAATTCAAGGCATGGATGCGCGACCTTCGGGACGACACAGCGAAAGCCAAAGTCAT
CACAAGGACCAAACAAGCTGCAGCAGGAAACTTCGGCGACGTGAAGCATTTCGATGGCATCTCCGAGATGCGCATCAACT
ATGGATCGGGTTACCGCGTCTACTACGCCAAGCAGGGCAAAACGGTTTATCTGCTCTTGATTGGCGGAGACAAAAGCTCC
CAAGATCGCGACATCAAAAAAGCCCAGAAACTCTGGAAAAGCATCAAGGGGTAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10198.74 Da        Isoelectric Point: 5.6784

>AT117568 WP_128897456.1 NZ_CP035300:c436531-436247 [Dyella sp. M7H15-1]
MTTHITPFDAAEYLDNEKVIAAYIKEVMETGDYDLLLSALGDVAKARGMTDIAKASGLSRESLYKAVRPGSKPQYETVDR
IIHALGLKLTVAVA

Download         Length: 285 bp

>AT117568 NZ_CP035300:c436531-436247 [Dyella sp. M7H15-1]
ATGACCACCCACATCACACCTTTCGACGCCGCCGAATATCTGGACAACGAGAAAGTCATTGCCGCCTATATCAAAGAGGT
CATGGAGACCGGCGACTATGATCTATTGCTGTCCGCCCTTGGCGACGTTGCCAAGGCGCGCGGCATGACCGACATCGCCA
AAGCCTCCGGGCTCAGCCGCGAGAGCCTCTACAAGGCCGTACGACCGGGTTCAAAGCCGCAATACGAAACCGTGGATCGC
ATCATTCATGCGCTGGGCCTGAAGCTGACCGTAGCGGTCGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References