Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 235164..235927 Replicon chromosome
Accession NZ_CP035300
Organism Dyella sp. M7H15-1

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag EO087_RS01250 Protein ID WP_205744460.1
Coordinates 235164..235652 (-) Length 163 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag EO087_RS01255 Protein ID WP_128897280.1
Coordinates 235655..235927 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EO087_RS01230 230175..231191 + 1017 WP_128897276.1 rod shape-determining protein MreC -
EO087_RS01235 231188..231676 + 489 WP_128897277.1 rod shape-determining protein MreD -
EO087_RS01240 231885..233906 + 2022 WP_128899759.1 penicillin-binding protein 2 -
EO087_RS01245 233903..235018 + 1116 WP_128897278.1 rod shape-determining protein RodA -
EO087_RS01250 235164..235652 - 489 WP_205744460.1 GNAT family N-acetyltransferase Toxin
EO087_RS01255 235655..235927 - 273 WP_128897280.1 DUF1778 domain-containing protein Antitoxin
EO087_RS01265 236648..237475 + 828 WP_128897282.1 SDR family oxidoreductase -
EO087_RS01270 237595..237780 - 186 WP_128897283.1 hypothetical protein -
EO087_RS01275 237989..238195 + 207 WP_128897284.1 hypothetical protein -
EO087_RS01280 238362..240275 + 1914 WP_128899760.1 M61 family metallopeptidase -
EO087_RS01285 240301..240591 - 291 WP_128897285.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(67-146)

Antitoxin

Vibrio phage ICP1, Orf50

(6-80)


Sequences

Toxin        


Download         Length: 163 a.a.        Molecular weight: 17817.56 Da        Isoelectric Point: 9.5783

>T117566 WP_205744460.1 NZ_CP035300:c235652-235164 [Dyella sp. M7H15-1]
MPLSAPQSLAATHRLDELNCGEPSLDDWLKRRALTNHLNGASRTFVVIDADQCVRGYYALAAGAVAHQEATGAVRRNMPD
PVPMMVLARLAVDARTQGIKLGAALLQDAVTRVRSVAENAGVRALFVHALNERAKQFYEHYGFRPSPMHPMTLMLPLKQH
PQ

Download         Length: 489 bp

>T117566 NZ_CP035300:c235652-235164 [Dyella sp. M7H15-1]
ATGCCGCTTTCAGCACCGCAGTCGCTCGCCGCGACGCATCGACTCGACGAGCTCAATTGCGGCGAGCCATCGCTGGACGA
TTGGCTGAAACGGCGCGCACTGACCAACCACCTCAACGGGGCCAGCCGCACCTTCGTTGTGATCGATGCAGACCAATGCG
TGCGTGGGTATTACGCTTTGGCAGCCGGGGCTGTCGCGCACCAGGAAGCCACCGGTGCCGTCCGGCGCAACATGCCTGAT
CCGGTGCCAATGATGGTGCTCGCAAGGCTCGCGGTGGATGCTCGCACTCAAGGCATCAAGCTTGGCGCGGCCTTGCTCCA
AGACGCCGTAACGCGCGTGCGATCTGTCGCAGAAAATGCTGGTGTCCGGGCATTGTTCGTTCATGCGTTGAACGAGCGTG
CGAAGCAGTTTTATGAGCACTATGGTTTTCGGCCATCGCCAATGCACCCAATGACCTTAATGCTCCCGCTGAAACAACAT
CCGCAATAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10166.65 Da        Isoelectric Point: 5.8189

>AT117566 WP_128897280.1 NZ_CP035300:c235927-235655 [Dyella sp. M7H15-1]
MRDASINLRALPEQRDLIDHAANLLGKNRSDFMLEAACERAKAIVLDQVFFALDENRFRQFTALLDAPQDANPGLERLMA
IKAPWSTNKP

Download         Length: 273 bp

>AT117566 NZ_CP035300:c235927-235655 [Dyella sp. M7H15-1]
ATGCGTGACGCCTCCATCAACTTGCGTGCGCTACCCGAGCAGCGCGACCTGATCGACCACGCCGCTAATCTGCTGGGCAA
GAATCGCTCAGACTTCATGCTCGAAGCTGCGTGCGAGCGTGCGAAAGCGATTGTGTTGGATCAGGTCTTTTTCGCCCTGG
ACGAAAACAGGTTCCGGCAGTTCACTGCATTGCTCGATGCGCCACAAGACGCCAATCCTGGCCTTGAGCGCCTGATGGCT
ATCAAGGCTCCGTGGAGTACGAACAAGCCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References