Detailed information of TA system TA117565

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/Phd(antitoxin)
• Location: 223456..224045
• Replicon: chromosome
• Accession: NZ_CP035300
• Organism: Dyella sp. M7H15-1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: EO087_RS01195
• Protein ID: WP_128897271.1
• Coordinates: 223456..223800 (-)
• Length: 115 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: EO087_RS01200
• Protein ID: WP_128897272.1
• Coordinates: 223788..224045 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EO087_RS01185	220768..221703	-	936	WP_128897269.1	CPBP family intramembrane metalloprotease	-
EO087_RS01190	221799..223400	-	1602	WP_128897270.1	peptide chain release factor 3	-
EO087_RS01195	223456..223800	-	345	WP_128897271.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
EO087_RS01200	223788..224045	-	258	WP_128897272.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
EO087_RS01205	224098..224457	+	360	WP_205744407.1	DUF3828 domain-containing protein	-
EO087_RS01210	224606..225238	-	633	WP_205744408.1	hypothetical protein	-
EO087_RS01215	225354..227519	-	2166	WP_128897273.1	elongation factor G	-
EO087_RS01220	227666..228601	-	936	WP_128897274.1	carbohydrate kinase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-87)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-73)

Sequences

Toxin

Protein

• Length: 115 a.a.
• Molecular weight: 13065.08 Da
• Isoelectric Point: 9.8167

>T117565 WP_128897271.1 NZ_CP035300:c223800-223456 [Dyella sp. M7H15-1]
MAEVIWTDPALSKLEEIADYIALENPLAANELVQRVFAHIGQLADHPESGSKPQELKGWRYRQIIEPPCRIFYRIDGDQV
FILYVMRSKKRLLSNKLDRRSSATPTRKIGRGAT

Nucleotide

• Length: 345 bp

>T117565 NZ_CP035300:c223800-223456 [Dyella sp. M7H15-1]
ATGGCTGAAGTGATTTGGACCGATCCGGCGCTCAGTAAGCTGGAAGAAATCGCCGATTACATCGCGCTCGAAAATCCCCT
CGCGGCAAACGAGCTCGTTCAACGCGTTTTCGCACACATAGGGCAGCTTGCTGACCATCCTGAGAGCGGCTCCAAGCCGC
AGGAGCTGAAGGGATGGCGTTATCGGCAAATCATCGAGCCACCATGCAGAATCTTCTACCGTATCGACGGGGATCAAGTT
TTCATCCTCTATGTCATGCGCAGCAAAAAGCGGCTTCTTTCCAATAAGCTGGACAGGCGAAGCTCAGCGACACCCACCCG
AAAAATCGGGCGAGGGGCAACCTGA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9965.58 Da
• Isoelectric Point: 10.1439

>AT117565 WP_128897272.1 NZ_CP035300:c224045-223788 [Dyella sp. M7H15-1]
MRTELVTTLKRQATELLADLERHREPILITQHGLPSAYLVDVVSYEAMQRRMKLLEGIARGERAVEEGRTLTHEQAKERL
KRWLK

Nucleotide

• Length: 258 bp

>AT117565 NZ_CP035300:c224045-223788 [Dyella sp. M7H15-1]
ATGCGCACCGAATTGGTCACCACCCTCAAACGCCAGGCCACTGAACTGTTGGCTGACCTGGAGCGCCACCGCGAGCCAAT
CCTGATAACCCAGCATGGCTTGCCTAGCGCTTATCTTGTCGATGTTGTGTCTTACGAAGCCATGCAGCGGCGCATGAAGC
TGCTGGAAGGCATTGCGCGCGGTGAACGTGCGGTGGAAGAAGGCCGCACCTTGACGCATGAACAGGCAAAGGAACGCCTC
AAACGATGGCTGAAGTGA