Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/YoeB(toxin) |
| Location | 1658676..1659134 | Replicon | chromosome |
| Accession | NZ_CP035298 | ||
| Organism | Micrococcus luteus strain ATCC 4698 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | C5CBH3 |
| Locus tag | ERB44_RS07955 | Protein ID | WP_010080486.1 |
| Coordinates | 1658880..1659134 (+) | Length | 85 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | C5CBH4 |
| Locus tag | ERB44_RS07950 | Protein ID | WP_010080485.1 |
| Coordinates | 1658676..1658879 (+) | Length | 68 a.a. |
Genomic Context
Location: 1655797..1656750 (954 bp)
Type: Others
Protein ID: WP_141117318.1
Type: Others
Protein ID: WP_141117318.1
Location: 1658676..1658879 (204 bp)
Type: Antitoxin
Protein ID: WP_010080485.1
Type: Antitoxin
Protein ID: WP_010080485.1
Location: 1658880..1659134 (255 bp)
Type: Toxin
Protein ID: WP_010080486.1
Type: Toxin
Protein ID: WP_010080486.1
Location: 1659136..1659702 (567 bp)
Type: Others
Protein ID: WP_010080487.1
Type: Others
Protein ID: WP_010080487.1
Location: 1662317..1662838 (522 bp)
Type: Others
Protein ID: WP_010080493.1
Type: Others
Protein ID: WP_010080493.1
Location: 1663047..1663703 (657 bp)
Type: Others
Protein ID: WP_231936623.1
Type: Others
Protein ID: WP_231936623.1
Location: 1656806..1657135 (330 bp)
Type: Others
Protein ID: Protein_1589
Type: Others
Protein ID: Protein_1589
Location: 1657172..1658515 (1344 bp)
Type: Others
Protein ID: WP_012751024.1
Type: Others
Protein ID: WP_012751024.1
Location: 1660012..1660794 (783 bp)
Type: Others
Protein ID: WP_010080489.1
Type: Others
Protein ID: WP_010080489.1
Location: 1660794..1661336 (543 bp)
Type: Others
Protein ID: WP_010080490.1
Type: Others
Protein ID: WP_010080490.1
Location: 1661333..1662058 (726 bp)
Type: Others
Protein ID: WP_029248323.1
Type: Others
Protein ID: WP_029248323.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ERB44_RS07935 (ERB44_07935) | 1655797..1656750 | + | 954 | WP_141117318.1 | hypothetical protein | - |
| ERB44_RS07940 (ERB44_07940) | 1656806..1657135 | - | 330 | Protein_1589 | transposase | - |
| ERB44_RS07945 (ERB44_07945) | 1657172..1658515 | - | 1344 | WP_012751024.1 | IS256-like element ISMlu11 family transposase | - |
| ERB44_RS07950 (ERB44_07950) | 1658676..1658879 | + | 204 | WP_010080485.1 | antitoxin | Antitoxin |
| ERB44_RS07955 (ERB44_07955) | 1658880..1659134 | + | 255 | WP_010080486.1 | Txe/YoeB family addiction module toxin | Toxin |
| ERB44_RS07960 (ERB44_07960) | 1659136..1659702 | + | 567 | WP_010080487.1 | mismatch-specific DNA-glycosylase | - |
| ERB44_RS07965 (ERB44_07965) | 1660012..1660794 | - | 783 | WP_010080489.1 | SCO1664 family protein | - |
| ERB44_RS07970 (ERB44_07970) | 1660794..1661336 | - | 543 | WP_010080490.1 | DUF3090 domain-containing protein | - |
| ERB44_RS07975 (ERB44_07975) | 1661333..1662058 | - | 726 | WP_029248323.1 | histidine phosphatase family protein | - |
| ERB44_RS12400 | 1662317..1662838 | + | 522 | WP_010080493.1 | hypothetical protein | - |
| ERB44_RS07985 (ERB44_07985) | 1663047..1663703 | + | 657 | WP_231936623.1 | aquaporin Z | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 85 a.a. Molecular weight: 9795.09 Da Isoelectric Point: 6.7156
>T117563 WP_010080486.1 NZ_CP035298:1658880-1659134 [Micrococcus luteus]
MRLVSDRSAWDDCTHWQTTDRKVLQRINTLIDAALRDPLDGIGKPEQLKYGAAGAWSRRITEEHRLVYLVDGEDLIILQA
RYHY
MRLVSDRSAWDDCTHWQTTDRKVLQRINTLIDAALRDPLDGIGKPEQLKYGAAGAWSRRITEEHRLVYLVDGEDLIILQA
RYHY
Download Length: 255 bp
>T117563 NZ_CP035298:1658880-1659134 [Micrococcus luteus]
ATGCGCCTCGTGTCGGACCGCTCCGCCTGGGATGACTGCACGCACTGGCAGACCACGGACCGCAAGGTCCTCCAACGGAT
CAACACCCTCATCGACGCCGCCCTGCGTGATCCCCTCGACGGGATCGGCAAACCCGAGCAGCTGAAGTACGGCGCGGCCG
GGGCATGGTCCCGACGCATCACGGAGGAGCACAGGCTCGTCTACCTCGTCGACGGCGAGGACCTGATCATCCTCCAGGCG
AGGTATCACTACTGA
ATGCGCCTCGTGTCGGACCGCTCCGCCTGGGATGACTGCACGCACTGGCAGACCACGGACCGCAAGGTCCTCCAACGGAT
CAACACCCTCATCGACGCCGCCCTGCGTGATCCCCTCGACGGGATCGGCAAACCCGAGCAGCTGAAGTACGGCGCGGCCG
GGGCATGGTCCCGACGCATCACGGAGGAGCACAGGCTCGTCTACCTCGTCGACGGCGAGGACCTGATCATCCTCCAGGCG
AGGTATCACTACTGA
Antitoxin
Download Length: 68 a.a. Molecular weight: 7374.33 Da Isoelectric Point: 4.5007
>AT117563 WP_010080485.1 NZ_CP035298:1658676-1658879 [Micrococcus luteus]
VPPEFDLADWYISRHHIAPEEAPMSISASEARKTLFPLIERVTADRDAVEIVSRKGNAVLMPADGDA
VPPEFDLADWYISRHHIAPEEAPMSISASEARKTLFPLIERVTADRDAVEIVSRKGNAVLMPADGDA
Download Length: 204 bp
>AT117563 NZ_CP035298:1658676-1658879 [Micrococcus luteus]
GTGCCTCCCGAGTTCGACCTCGCCGACTGGTACATAAGCAGGCACCACATCGCGCCGGAGGAGGCCCCCATGTCCATCAG
TGCCAGTGAAGCCCGCAAGACCCTGTTCCCGCTCATCGAGCGAGTGACTGCGGACCGCGACGCCGTCGAGATCGTCTCCC
GCAAGGGCAACGCCGTTCTCATGCCCGCGGACGGGGACGCCTGA
GTGCCTCCCGAGTTCGACCTCGCCGACTGGTACATAAGCAGGCACCACATCGCGCCGGAGGAGGCCCCCATGTCCATCAG
TGCCAGTGAAGCCCGCAAGACCCTGTTCCCGCTCATCGAGCGAGTGACTGCGGACCGCGACGCCGTCGAGATCGTCTCCC
GCAAGGGCAACGCCGTTCTCATGCCCGCGGACGGGGACGCCTGA