Detailed information of TA system TA117539

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YafQ-DinJ
• Location: 904812..905358
• Replicon: chromosome
• Accession: NZ_CP035283
• Organism: Caproiciproducens sp. NJN-50

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: EQM14_RS04385
• Protein ID: WP_128741807.1
• Coordinates: 905080..905358 (+)
• Length: 93 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: EQM14_RS04380
• Protein ID: WP_128741806.1
• Coordinates: 904812..905087 (+)
• Length: 92 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EQM14_RS04360	899874..901565	-	1692	WP_128741802.1	retron Ec67 family RNA-directed DNA polymerase/endonuclease	-
EQM14_RS04365	902250..902867	+	618	WP_128741803.1	hypothetical protein	-
EQM14_RS04370	902848..904020	+	1173	WP_128741804.1	XRE family transcriptional regulator	-
EQM14_RS04375	904239..904475	-	237	WP_128741805.1	hypothetical protein	-
EQM14_RS04380	904812..905087	+	276	WP_128741806.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
EQM14_RS04385	905080..905358	+	279	WP_128741807.1	type II toxin-antitoxin system YafQ family toxin	Toxin
EQM14_RS04390	905832..906473	+	642	WP_128741808.1	hypothetical protein	-
EQM14_RS04395	906774..907376	-	603	WP_128741809.1	tyrosine-type recombinase/integrase	-
EQM14_RS04400	907830..908558	+	729	WP_128741810.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	892422..908558	16136

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, YafQ-like toxin (1-92)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (6-90)

Sequences

Toxin

Protein

• Length: 93 a.a.
• Molecular weight: 10874.67 Da
• Isoelectric Point: 9.8254

>T117539 WP_128741807.1 NZ_CP035283:905080-905358 [Caproiciproducens sp. NJN-50]
MLKIEYQGQFKKDYKEAIKRGYNPELLAEVVSILANEQPLPPKYKDHNLTNSRNYKGMRECHIQPDWLLVYQISKKVLIL
RLIRTGSHSDLF

Nucleotide

• Length: 279 bp

>T117539 NZ_CP035283:905080-905358 [Caproiciproducens sp. NJN-50]
ATGCTTAAGATCGAATATCAAGGGCAATTCAAAAAAGACTACAAAGAGGCAATAAAGAGGGGATACAACCCGGAGCTGCT
GGCCGAAGTGGTTTCCATACTGGCGAACGAACAGCCCCTTCCTCCGAAGTACAAAGACCACAACCTGACGAACTCCCGGA
ACTACAAGGGCATGAGAGAGTGTCATATTCAACCTGACTGGCTGCTTGTCTATCAGATCAGCAAGAAGGTCCTTATTTTG
CGGCTGATTAGAACAGGCAGCCATAGTGATTTATTTTAG

Antitoxin

Protein

• Length: 92 a.a.
• Molecular weight: 10139.42 Da
• Isoelectric Point: 4.3785

>AT117539 WP_128741806.1 NZ_CP035283:904812-905087 [Caproiciproducens sp. NJN-50]
MSVKSDTSMTIRMNKDVKQQAQQIFSELGLDMTTAVNVFLRQAIRYHGFPFDVTLDTPNEVTLAAMDDSEKGRDVHGPFD
SVSALMEDLNA

Nucleotide

• Length: 276 bp

>AT117539 NZ_CP035283:904812-905087 [Caproiciproducens sp. NJN-50]
ATGTCTGTAAAATCCGATACCAGCATGACGATCAGAATGAACAAGGATGTAAAACAGCAGGCCCAACAGATTTTTTCAGA
GCTGGGTTTGGATATGACTACCGCCGTCAATGTGTTTCTGCGTCAAGCTATCCGTTATCACGGGTTTCCGTTCGATGTGA
CGCTGGACACCCCAAACGAGGTTACGCTGGCCGCTATGGATGACTCGGAGAAGGGCAGAGATGTTCATGGTCCCTTTGAC
AGTGTGTCGGCGCTGATGGAGGACTTGAATGCTTAA