Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-Axe/YoeB-RelB
Location 531832..532357 Replicon chromosome
Accession NZ_CP035281
Organism Aminipila sp. JN-18

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag EQM06_RS02440 Protein ID WP_128744835.1
Coordinates 531832..532092 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name Axe Uniprot ID -
Locus tag EQM06_RS02445 Protein ID WP_128744836.1
Coordinates 532085..532357 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EQM06_RS02420 528279..528746 - 468 WP_128744832.1 hypothetical protein -
EQM06_RS12840 528895..529047 + 153 WP_164914319.1 hypothetical protein -
EQM06_RS02425 529338..529874 + 537 WP_128746767.1 dCTP deaminase -
EQM06_RS02430 529931..530800 + 870 WP_128744833.1 hypothetical protein -
EQM06_RS02435 531365..531613 + 249 WP_128744834.1 phage holin -
EQM06_RS02440 531832..532092 - 261 WP_128744835.1 Txe/YoeB family addiction module toxin Toxin
EQM06_RS02445 532085..532357 - 273 WP_128744836.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
EQM06_RS02450 532504..532656 - 153 WP_128746768.1 tyrosine-type recombinase/integrase -
EQM06_RS02455 532854..533318 - 465 WP_128744837.1 glyoxalase -
EQM06_RS02465 533752..534246 + 495 WP_128744838.1 DUF1836 domain-containing protein -
EQM06_RS12965 534464..534754 - 291 WP_205666579.1 hypothetical protein -
EQM06_RS12970 534955..535200 + 246 WP_205666611.1 spore coat associated protein CotJA -
EQM06_RS02475 535197..535445 + 249 WP_164914320.1 spore coat protein CotJB -
EQM06_RS02480 535448..535870 + 423 WP_128744841.1 manganese catalase family protein -
EQM06_RS02485 536093..536350 - 258 WP_128744842.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-70)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10290.64 Da        Isoelectric Point: 7.2738

>T117537 WP_128744835.1 NZ_CP035281:c532092-531832 [Aminipila sp. JN-18]
MNKMFSGNAWEDYTLWLQEDHKVLRRINDILKDIERSGNEGINRPEPLKHSLSGYWSRRITEKYRLVYKIADDTIYILGC
KGHYDD

Download         Length: 261 bp

>T117537 NZ_CP035281:c532092-531832 [Aminipila sp. JN-18]
ATGAATAAAATGTTTTCAGGAAATGCATGGGAGGACTACACCTTATGGTTGCAAGAAGATCACAAAGTCTTACGGCGTAT
AAATGATATTCTCAAAGACATTGAACGAAGCGGAAATGAAGGGATCAACAGACCTGAACCTTTAAAGCATTCTCTATCCG
GTTACTGGAGCCGTAGGATTACCGAAAAATACCGTTTAGTATATAAAATTGCGGATGATACCATTTATATTTTAGGCTGT
AAGGGTCACTATGATGATTAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10466.84 Da        Isoelectric Point: 4.3885

>AT117537 WP_128744836.1 NZ_CP035281:c532357-532085 [Aminipila sp. JN-18]
MLAVNYSTIRNNLKNYCDLVTDNCETVIVTRKDEKNVVMISLDEYNNMLENLFIMSDKVNYARLLESKEQFDKHQGVTKT
TEELEALANE

Download         Length: 273 bp

>AT117537 NZ_CP035281:c532357-532085 [Aminipila sp. JN-18]
ATGTTAGCCGTAAACTACTCTACGATTCGCAATAACTTAAAAAATTATTGCGATTTAGTAACAGACAACTGTGAAACTGT
AATAGTTACACGAAAAGATGAAAAAAACGTAGTGATGATTAGTCTTGATGAATACAACAATATGCTTGAAAACTTATTTA
TTATGAGTGATAAAGTGAATTATGCCAGGCTTTTAGAAAGCAAAGAACAATTTGACAAACACCAGGGCGTGACTAAAACT
ACAGAAGAGTTAGAGGCTCTAGCCAATGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References