Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 675538..675683 Replicon chromosome
Accession NZ_CP035210
Organism Klebsiella pneumoniae strain TH164

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 675574..675676 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 675538..675683 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EQH51_RS03235 670668..672728 + 2061 WP_004151449.1 oligopeptidase B -
EQH51_RS03240 672732..673391 - 660 WP_002911407.1 exodeoxyribonuclease X -
EQH51_RS03245 673470..673700 - 231 WP_002911406.1 DNA polymerase III subunit theta -
EQH51_RS03250 673813..674187 + 375 WP_004151448.1 CopC domain-containing protein YobA -
EQH51_RS03255 674191..675060 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
EQH51_RS03260 675077..675415 + 339 WP_002911404.1 YebY family protein -
- 675538..675683 - 146 - - Antitoxin
- 675574..675676 + 103 - - Toxin
EQH51_RS03270 676051..676194 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
EQH51_RS03275 676299..677267 - 969 WP_004151446.1 VirK/YbjX family protein -
EQH51_RS03280 677424..678077 + 654 WP_032432437.1 protein-serine/threonine phosphatase -
EQH51_RS03285 678074..678265 - 192 WP_002911395.1 YebW family protein -
EQH51_RS03290 678363..678602 - 240 WP_002911393.1 YebV family protein -
EQH51_RS03295 678718..680151 - 1434 WP_021440382.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T117384 NZ_CP035210:675574-675676 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT117384 NZ_CP035210:c675683-675538 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References