Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4577160..4577305 Replicon chromosome
Accession NZ_CP035202
Organism Klebsiella pneumoniae strain LH94

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4577167..4577269 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4577160..4577305 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EQH49_RS22405 4572691..4574124 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
EQH49_RS22410 4574240..4574479 + 240 WP_002911393.1 YebV family protein -
EQH49_RS22415 4574577..4574768 + 192 WP_002911395.1 YebW family protein -
EQH49_RS22420 4574765..4575418 - 654 WP_064145335.1 protein-serine/threonine phosphatase -
EQH49_RS22425 4575575..4576543 + 969 WP_004151446.1 VirK/YbjX family protein -
EQH49_RS22430 4576648..4576791 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 4577160..4577305 + 146 - - Antitoxin
- 4577167..4577269 - 103 - - Toxin
EQH49_RS22440 4577428..4577766 - 339 WP_002911404.1 YebY family protein -
EQH49_RS22445 4577783..4578652 - 870 WP_004189267.1 copper homeostasis membrane protein CopD -
EQH49_RS22450 4578656..4579030 - 375 WP_004151448.1 CopC domain-containing protein YobA -
EQH49_RS22455 4579143..4579373 + 231 WP_002911406.1 DNA polymerase III subunit theta -
EQH49_RS22460 4579452..4580111 + 660 WP_002911407.1 exodeoxyribonuclease X -
EQH49_RS22465 4580115..4582175 - 2061 WP_064145333.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T117358 NZ_CP035202:c4577269-4577167 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT117358 NZ_CP035202:4577160-4577305 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References