Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1020477..1020622 | Replicon | chromosome |
| Accession | NZ_CP035196 | ||
| Organism | Klebsiella pneumoniae strain LH375 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1020513..1020615 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1020477..1020622 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EP126_RS04890 | 1015607..1017667 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| EP126_RS04895 | 1017671..1018330 | - | 660 | WP_021440386.1 | exodeoxyribonuclease X | - |
| EP126_RS04900 | 1018409..1018639 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| EP126_RS04905 | 1018752..1019126 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| EP126_RS04910 | 1019130..1019999 | + | 870 | WP_038435445.1 | copper homeostasis membrane protein CopD | - |
| EP126_RS04915 | 1020016..1020354 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 1020477..1020622 | - | 146 | - | - | Antitoxin |
| - | 1020513..1020615 | + | 103 | - | - | Toxin |
| EP126_RS04925 | 1020990..1021133 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| EP126_RS04930 | 1021238..1022206 | - | 969 | WP_167876367.1 | VirK/YbjX family protein | - |
| EP126_RS04935 | 1022363..1023016 | + | 654 | WP_019725444.1 | protein-serine/threonine phosphatase | - |
| EP126_RS04940 | 1023013..1023204 | - | 192 | WP_002911395.1 | YebW family protein | - |
| EP126_RS04945 | 1023302..1023541 | - | 240 | WP_002911393.1 | YebV family protein | - |
| EP126_RS04950 | 1023657..1025090 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T117327 NZ_CP035196:1020513-1020615 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT117327 NZ_CP035196:c1020622-1020477 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
