Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 820832..820977 Replicon chromosome
Accession NZ_CP035194
Organism Klebsiella pneumoniae strain LH102-A

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 820839..820941 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 820832..820977 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EPO92_RS04140 816364..817797 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
EPO92_RS04145 817913..818152 + 240 WP_002911393.1 YebV family protein -
EPO92_RS04150 818250..818441 + 192 WP_002911395.1 YebW family protein -
EPO92_RS04155 818438..819091 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
EPO92_RS04160 819248..820216 + 969 WP_074426446.1 VirK/YbjX family protein -
EPO92_RS04165 820321..820464 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 820832..820977 + 146 - - Antitoxin
- 820839..820941 - 103 - - Toxin
EPO92_RS04175 821100..821438 - 339 WP_016529031.1 YebY family protein -
EPO92_RS04180 821455..822324 - 870 WP_004189267.1 copper homeostasis membrane protein CopD -
EPO92_RS04185 822328..822702 - 375 WP_004151448.1 CopC domain-containing protein YobA -
EPO92_RS04190 822815..823045 + 231 WP_002911406.1 DNA polymerase III subunit theta -
EPO92_RS04195 823124..823783 + 660 WP_002911407.1 exodeoxyribonuclease X -
EPO92_RS04200 823787..825847 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T117311 NZ_CP035194:c820941-820839 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT117311 NZ_CP035194:820832-820977 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References