Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PhoH-vapB/-
Location 1631615..1633421 Replicon chromosome
Accession NZ_CP035130
Organism Gudongella oleilytica strain W6

Toxin (Protein)


Gene name PhoH Uniprot ID -
Locus tag EC328_RS07815 Protein ID WP_128426260.1
Coordinates 1631615..1632982 (-) Length 456 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag EC328_RS07820 Protein ID WP_128426261.1
Coordinates 1633071..1633421 (-) Length 117 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EC328_RS07790 1626696..1628222 - 1527 WP_206363966.1 ATP-binding cassette domain-containing protein -
EC328_RS07795 1628466..1629608 - 1143 WP_128426256.1 BMP family ABC transporter substrate-binding protein -
EC328_RS07800 1629943..1630230 + 288 WP_128426257.1 hypothetical protein -
EC328_RS07805 1630242..1631180 + 939 WP_128426258.1 ArsA family ATPase -
EC328_RS07810 1631361..1631558 + 198 WP_164906070.1 cold-shock protein -
EC328_RS07815 1631615..1632982 - 1368 WP_128426260.1 PhoH family protein Toxin
EC328_RS07820 1633071..1633421 - 351 WP_128426261.1 DUF488 family protein Antitoxin
EC328_RS07825 1633442..1634746 - 1305 WP_128426262.1 alkaline phosphatase family protein -
EC328_RS07830 1634765..1636006 - 1242 WP_128426263.1 MFS transporter -
EC328_RS07835 1636139..1636588 + 450 WP_128426264.1 hypothetical protein -
EC328_RS07840 1636647..1637483 - 837 WP_128426265.1 NAD(+) diphosphatase -
EC328_RS07845 1637500..1638156 - 657 WP_128426266.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1631361..1711944 80583


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-140)

Antitoxin

Protein of unknown function DUF488

(5-115)


Sequences

Toxin        


Download         Length: 456 a.a.        Molecular weight: 51490.94 Da        Isoelectric Point: 5.3020

>T117250 WP_128426260.1 NZ_CP035130:c1632982-1631615 [Gudongella oleilytica]
MKKTYVLDTNVIIQSPLALSSFEDNKVVLPVAVLEELDKLKNDDAERGSNARQAIRFLEDLRLMGNLYEGVPLESGGLIK
IETNYSNVDIPSGFHHDSNDNRILKVCKGLMDDSENVILVTKDIIVRLKAQMMGVVAEDFTTEQSPVFEKQYTGRMDAYT
SDKAMSEFKKRGINPENIFTFQGFDRTPIEPVPNQFFILHSETNDKKTLLGRYDGVKIVPLRSINEEPFGVKPKNVGQRF
LQEALMQDADVAPLVIIKGTAGTAKTFYSLAVGLQHTYEPSSKRYRKILITRPNVQFDEDIGFLPGTEEERIAPYLRPII
DNLEILVDRNENERYKNEKQLRDKIDELFYRGIIVAEAMNFIRGRSITNTYLIIDEAQNLTPKQVKGIITRVGKGTKVVL
LGDPQQIDHPLLDEKTNGLSYASEKMKGSELCFQLTMLPDECLRSTLAQDASSRM

Download         Length: 1368 bp

>T117250 NZ_CP035130:c1632982-1631615 [Gudongella oleilytica]
ATGAAGAAAACCTACGTTCTTGACACAAATGTTATCATTCAGTCTCCATTAGCTCTGTCCTCGTTTGAGGACAACAAGGT
TGTTTTACCAGTCGCCGTTCTTGAAGAGCTTGATAAGCTAAAAAATGACGATGCTGAACGAGGATCAAACGCACGCCAGG
CGATCCGCTTCCTGGAGGATCTGCGATTAATGGGCAACCTGTACGAAGGAGTACCGCTGGAAAGCGGAGGACTCATAAAA
ATTGAAACAAATTATTCCAATGTCGATATTCCCTCAGGCTTTCACCACGATTCTAACGACAACAGAATATTAAAGGTTTG
TAAAGGCCTTATGGATGACAGCGAAAATGTCATCCTGGTAACTAAGGACATTATCGTAAGACTTAAGGCTCAGATGATGG
GTGTTGTAGCAGAGGATTTCACCACAGAGCAGTCACCTGTATTCGAGAAGCAGTATACAGGTAGAATGGATGCATATACA
AGCGATAAAGCAATGTCAGAGTTTAAGAAAAGAGGTATAAATCCTGAAAATATATTTACCTTCCAGGGATTTGACAGGAC
CCCTATTGAGCCGGTGCCCAATCAATTTTTTATATTGCACTCTGAAACCAATGATAAAAAAACTCTCCTTGGAAGATATG
ACGGAGTGAAGATTGTGCCCTTAAGGAGTATAAACGAGGAGCCCTTTGGAGTCAAGCCAAAGAACGTTGGACAGAGATTC
CTCCAGGAAGCTCTCATGCAGGATGCAGATGTTGCACCATTGGTAATTATCAAGGGGACTGCAGGAACAGCAAAAACCTT
CTACTCACTGGCAGTCGGACTACAGCATACCTATGAGCCTTCATCAAAGCGCTACAGGAAGATACTGATTACAAGGCCAA
ACGTGCAATTTGATGAGGATATCGGCTTTCTCCCAGGCACTGAGGAGGAGAGGATAGCACCATACCTAAGACCGATAATT
GATAATCTTGAAATACTTGTCGACAGGAATGAAAACGAAAGATACAAGAATGAAAAACAACTTAGGGATAAAATAGATGA
ACTTTTCTACAGAGGGATCATTGTAGCTGAGGCTATGAACTTCATAAGAGGCCGATCAATAACAAATACATATTTGATAA
TCGATGAAGCACAGAACCTTACTCCAAAGCAGGTCAAGGGGATAATAACAAGAGTAGGGAAAGGTACGAAGGTAGTACTA
TTAGGTGATCCACAGCAGATAGATCATCCACTTCTGGATGAAAAAACCAATGGACTGAGCTATGCCTCAGAGAAGATGAA
GGGCAGTGAACTATGCTTTCAGTTGACTATGCTTCCTGATGAATGTCTTAGATCAACCTTGGCTCAGGACGCATCCAGCA
GGATGTGA

Antitoxin


Download         Length: 117 a.a.        Molecular weight: 13619.50 Da        Isoelectric Point: 6.2435

>AT117250 WP_128426261.1 NZ_CP035130:c1633421-1633071 [Gudongella oleilytica]
MYDIKVKRIYDEPEADDGLRVLVDRLWARGITKEKAMLDIWAKEIAPSNELRKEYHNSWDASSFRDRYLEELRSNPSAEG
IKEIIKGELINSNVTLLTSAKNLDYNHCHVIKEWLK

Download         Length: 351 bp

>AT117250 NZ_CP035130:c1633421-1633071 [Gudongella oleilytica]
ATGTACGATATAAAAGTCAAACGGATCTATGATGAGCCTGAGGCAGATGACGGTCTTAGAGTGCTTGTCGACAGACTTTG
GGCAAGAGGAATAACGAAAGAGAAAGCAATGCTTGATATATGGGCAAAGGAAATTGCCCCGAGCAATGAACTTAGGAAGG
AGTACCATAACTCATGGGATGCATCAAGCTTCAGGGACAGATACCTTGAAGAGCTCCGTAGCAATCCATCTGCGGAAGGG
ATCAAAGAGATTATCAAGGGGGAACTCATAAACTCAAACGTTACTCTTCTGACATCTGCAAAGAATTTGGACTACAATCA
CTGTCACGTGATCAAGGAATGGCTTAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References