Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 571424..571994 Replicon chromosome
Accession NZ_CP035105
Organism Helicobacter pylori strain Hpbs2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag EM803_RS02880 Protein ID WP_128481199.1
Coordinates 571722..571994 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag EM803_RS02875 Protein ID WP_128481198.1
Coordinates 571424..571735 (+) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EM803_RS02840 566445..566681 + 237 WP_000335472.1 HypC/HybG/HupF family hydrogenase formation chaperone -
EM803_RS02845 566700..567812 + 1113 WP_128481196.1 hydrogenase formation protein HypD -
EM803_RS02850 567763..568395 - 633 WP_128481197.1 hypothetical protein -
EM803_RS02865 568803..571023 + 2221 Protein_529 Hop family adhesin BabA -
EM803_RS02875 571424..571735 + 312 WP_128481198.1 hypothetical protein Antitoxin
EM803_RS02880 571722..571994 + 273 WP_128481199.1 type II toxin-antitoxin system YafQ family toxin Toxin
EM803_RS02885 572096..572620 - 525 WP_001135602.1 acyl-CoA thioesterase -
EM803_RS02890 572760..573602 + 843 WP_128481200.1 SDR family oxidoreductase -
EM803_RS02895 573595..574575 + 981 WP_000921482.1 iron ABC transporter permease -
EM803_RS02900 574575..575342 + 768 WP_128481201.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(1-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10625.65 Da        Isoelectric Point: 9.9378

>T117201 WP_128481199.1 NZ_CP035105:571722-571994 [Helicobacter pylori]
MLMIETNKKFDKDLKILVKNGFDLKLLYKVVENLAKEQPLDPKYKDHPLKGALKNFRECHLKPDLLLVYQIKKQENTLFL
VRLGSHSELF

Download         Length: 273 bp

>T117201 NZ_CP035105:571722-571994 [Helicobacter pylori]
ATGTTGATGATTGAAACCAATAAAAAATTTGATAAGGATCTTAAAATTCTTGTTAAAAACGGGTTTGATTTAAAGCTTTT
ATATAAAGTGGTTGAAAATTTAGCCAAAGAGCAACCCCTAGATCCCAAATACAAAGACCACCCGCTCAAAGGCGCTTTAA
AAAATTTTAGGGAGTGCCACCTGAAACCGGATTTATTGCTTGTCTATCAAATTAAAAAACAAGAAAACACTCTCTTTTTA
GTAAGGTTAGGCAGTCATAGCGAGCTGTTTTAA

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 12386.33 Da        Isoelectric Point: 10.2819

>AT117201 WP_128481198.1 NZ_CP035105:571424-571735 [Helicobacter pylori]
MPNSPTKKDYTRYSEKQLFNFLNSIKTKQKRALEKLKEIQAQKQRIKKALQFKALHLTENGYTIEEEREILVRAKDIKNH
LCFKSVEDFKKHCENLRFKNVDD

Download         Length: 312 bp

>AT117201 NZ_CP035105:571424-571735 [Helicobacter pylori]
ATGCCTAATTCTCCCACCAAAAAAGACTACACACGATACAGCGAAAAACAGCTTTTTAACTTTTTAAATTCTATCAAGAC
CAAACAAAAAAGAGCGTTAGAAAAATTGAAAGAAATCCAAGCTCAAAAACAAAGAATTAAAAAAGCCCTCCAATTTAAAG
CGCTCCATTTAACCGAAAACGGATACACCATAGAAGAAGAGCGAGAAATCTTAGTAAGGGCTAAAGACATCAAGAACCAC
CTTTGTTTTAAAAGCGTAGAGGATTTTAAAAAGCATTGTGAAAACTTAAGATTTAAAAATGTTGATGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References