Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 2675695..2676368 Replicon chromosome
Accession NZ_CP035093
Organism Brevundimonas diminuta strain ATCC(B) 19146

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag EQG53_RS13250 Protein ID WP_003165189.1
Coordinates 2675695..2676117 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag EQG53_RS13255 Protein ID WP_003165190.1
Coordinates 2676114..2676368 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EQG53_RS13225 2671626..2671760 + 135 WP_128720133.1 benenodin family lasso peptide -
EQG53_RS13230 2671840..2672469 + 630 WP_157683871.1 lasso peptide biosynthesis B2 protein -
EQG53_RS13235 2672469..2673593 + 1125 WP_128720134.1 hypothetical protein -
EQG53_RS13245 2675004..2675486 - 483 WP_128720135.1 STN domain-containing protein -
EQG53_RS13250 2675695..2676117 - 423 WP_003165189.1 type II toxin-antitoxin system VapC family toxin Toxin
EQG53_RS13255 2676114..2676368 - 255 WP_003165190.1 hypothetical protein Antitoxin
EQG53_RS13260 2676558..2677508 - 951 WP_040345555.1 FecR domain-containing protein -
EQG53_RS13265 2677508..2678068 - 561 WP_003165192.1 sigma-70 family RNA polymerase sigma factor -
EQG53_RS13270 2678505..2679437 + 933 WP_003165193.1 AraC family transcriptional regulator -
EQG53_RS13275 2679557..2680012 + 456 WP_003169270.1 helix-turn-helix domain-containing protein -
EQG53_RS13280 2680051..2680128 + 78 Protein_2614 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
EQG53_RS13285 2680459..2680983 + 525 WP_128720136.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-121)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 14745.03 Da        Isoelectric Point: 6.4815

>T117187 WP_003165189.1 NZ_CP035093:c2676117-2675695 [Brevundimonas diminuta]
MILLDTNVISETMRPEPHPDVVRWLDEQAAETLYLSSVTVAEMLFGIGVLPAGRRKDRLAAAVDGIVALFGDRILAFDLV
AARHHAALAVKARTAGKGFPTPDGYIAAIAAAHGFAVATRDVSAFAAAGLPVMNPWASPN

Download         Length: 423 bp

>T117187 NZ_CP035093:c2676117-2675695 [Brevundimonas diminuta]
ATGATCCTGCTCGACACCAACGTCATCTCCGAGACGATGAGGCCGGAACCCCATCCCGACGTCGTCAGATGGCTCGATGA
ACAAGCCGCCGAAACCCTATACCTTTCCAGCGTCACGGTTGCGGAAATGCTGTTCGGAATCGGTGTGCTGCCGGCGGGAC
GTCGCAAGGACAGGCTCGCGGCGGCTGTCGACGGGATCGTCGCTCTCTTTGGCGACCGCATCCTTGCCTTTGACCTCGTA
GCGGCCCGCCATCACGCAGCGCTTGCGGTCAAGGCGCGCACGGCGGGCAAGGGCTTTCCGACGCCAGATGGGTATATTGC
GGCCATCGCTGCTGCCCACGGTTTTGCTGTCGCCACACGCGACGTCAGCGCGTTCGCCGCCGCGGGTCTGCCTGTCATGA
ATCCCTGGGCGTCACCCAACTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9159.40 Da        Isoelectric Point: 11.3030

>AT117187 WP_003165190.1 NZ_CP035093:c2676368-2676114 [Brevundimonas diminuta]
MAAVTIRNLSEETHRALKLRAASHGRSAEAEIRDILERAVRPAKRVRLGSAMAAAGRQAGVTNADVEALEQHRDRKPASP
MSFE

Download         Length: 255 bp

>AT117187 NZ_CP035093:c2676368-2676114 [Brevundimonas diminuta]
ATGGCTGCTGTCACCATTCGCAATCTCTCGGAGGAGACCCATCGCGCCCTCAAGCTGCGGGCCGCCAGTCATGGCCGTAG
CGCAGAAGCCGAAATCCGCGACATTCTTGAGAGGGCTGTTCGGCCCGCCAAACGCGTCCGTCTGGGGTCGGCGATGGCTG
CGGCCGGGCGGCAGGCAGGCGTCACCAACGCTGATGTGGAAGCGCTCGAACAGCATCGCGATCGCAAGCCCGCGTCCCCG
ATGAGCTTCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References