Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type VI Classification (family/domain) socAB/DUF4065(antitoxin)
Location 2015669..2016914 Replicon chromosome
Accession NZ_CP035090
Organism Paracoccus denitrificans strain ATCC 19367

Toxin (Protein)


Gene name socB Uniprot ID -
Locus tag EO213_RS10185 Protein ID WP_128493026.1
Coordinates 2015669..2016370 (-) Length 234 a.a.

Antitoxin (Protein)


Gene name socA Uniprot ID -
Locus tag EO213_RS10190 Protein ID WP_011746798.1
Coordinates 2016363..2016914 (-) Length 184 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EO213_RS10175 2013759..2014667 + 909 WP_011746795.1 hypothetical protein -
EO213_RS10180 2014667..2015578 + 912 WP_011746796.1 DNA polymerase III subunit epsilon -
EO213_RS10185 2015669..2016370 - 702 WP_128493026.1 hypothetical protein Toxin
EO213_RS10190 2016363..2016914 - 552 WP_011746798.1 SocA family protein Antitoxin
EO213_RS10195 2017257..2017748 - 492 Protein_2000 type I restriction endonuclease subunit R -
EO213_RS10200 2017903..2018142 - 240 WP_074810467.1 hypothetical protein -
EO213_RS10205 2018157..2018987 - 831 WP_011746800.1 hypothetical protein -
EO213_RS10210 2019074..2019328 + 255 WP_011746801.1 helix-turn-helix domain-containing protein -
EO213_RS10215 2019519..2019719 + 201 WP_074810464.1 hypothetical protein -
EO213_RS10220 2019910..2020116 + 207 WP_198140517.1 helix-turn-helix domain-containing protein -
EO213_RS10225 2020328..2020855 + 528 WP_011746803.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2006639..2031770 25131


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Antitoxin SocA-like, Panacea domain

(30-133)


Sequences

Toxin        


Download         Length: 234 a.a.        Molecular weight: 26805.37 Da        Isoelectric Point: 5.4840

>T117182 WP_128493026.1 NZ_CP035090:c2016370-2015669 [Paracoccus denitrificans]
MPDIDLARIAPQRDDMKRKSLEQMKGGFSTFSYKPVRACFSDIFNIQPDLDLGSADPTPWTVIESELRKRSKSDEEFNYN
RRVALGLHDFATSGRVFGRRQEFFPLSMGMGQKVTFWLPMILAIDEQASALFIEPRRTRGLTAEGRRFALSMMHERIRAA
DEDFADVRLTIVQFSDPSDDRRAVRLHTDEGVELYSREDLEQMVASTYEMWRDVLEERENKARGKATGTGPLI

Download         Length: 702 bp

>T117182 NZ_CP035090:c2016370-2015669 [Paracoccus denitrificans]
TTGCCTGACATTGACCTTGCGCGCATCGCGCCCCAACGCGATGACATGAAACGCAAGAGCTTGGAGCAGATGAAGGGCGG
TTTCTCGACCTTCTCCTACAAGCCGGTGCGCGCTTGCTTCTCTGACATCTTCAACATCCAGCCCGACTTGGACCTAGGGT
CAGCCGATCCGACGCCTTGGACTGTGATTGAGTCCGAGTTGCGGAAGCGCAGCAAGTCGGACGAGGAATTCAACTACAAC
CGGCGCGTTGCCCTTGGCCTGCACGACTTTGCGACTTCTGGTCGGGTCTTCGGGCGACGGCAGGAGTTCTTCCCGCTGTC
GATGGGCATGGGGCAGAAAGTCACATTCTGGCTGCCGATGATTCTCGCCATCGATGAGCAGGCAAGCGCCCTGTTTATCG
AACCGCGCCGCACCAGAGGCTTAACCGCCGAAGGCCGCAGGTTCGCGTTATCGATGATGCATGAGCGCATCCGGGCCGCT
GACGAGGACTTTGCCGACGTTCGATTGACCATCGTGCAGTTTAGCGACCCGTCTGATGATCGGCGCGCGGTCAGGCTCCA
CACGGACGAGGGCGTTGAACTCTACTCCCGCGAGGATTTGGAGCAGATGGTGGCTTCGACCTATGAGATGTGGCGCGATG
TGCTGGAAGAGCGCGAGAATAAGGCGCGGGGAAAGGCGACTGGTACTGGCCCGCTGATCTGA

Antitoxin


Download         Length: 184 a.a.        Molecular weight: 20217.20 Da        Isoelectric Point: 9.9688

>AT117182 WP_011746798.1 NZ_CP035090:c2016914-2016363 [Paracoccus denitrificans]
MSGPYDPRAIANLMLDEADRRGWKITNLALQKLLYFAHGIHLTKTKRPLVSGYFEAWQYGPVHPAVYRAFKPSGSAPIIN
RAAAKDPLTGKTRDLPKPTDLEVIDLVSDVMRSYGHLPPGRLVDLSHAKDSPWSVVVDKARTDVAFGMRIPDDVIIARFR
HHKVSVGTSPRAGEPPSDDAPFA

Download         Length: 552 bp

>AT117182 NZ_CP035090:c2016914-2016363 [Paracoccus denitrificans]
ATGAGTGGGCCATACGATCCGAGGGCAATCGCGAACCTCATGCTGGACGAGGCGGATCGGCGCGGCTGGAAAATCACGAA
CCTTGCCCTCCAGAAGCTGCTCTACTTCGCTCACGGCATACACCTAACCAAGACGAAGCGCCCGCTCGTGTCGGGCTACT
TCGAGGCGTGGCAGTACGGCCCCGTGCATCCAGCCGTCTATCGGGCGTTCAAGCCGTCAGGCTCCGCACCCATCATCAAC
CGGGCGGCCGCGAAAGACCCGCTCACAGGCAAGACGCGTGATCTGCCAAAGCCGACGGACCTTGAAGTCATCGACCTCGT
GTCCGACGTGATGAGATCATACGGGCACCTCCCGCCTGGACGGCTGGTCGATCTGTCCCACGCGAAGGACTCGCCGTGGT
CGGTGGTCGTGGACAAAGCACGAACAGATGTTGCTTTTGGGATGCGGATACCGGATGATGTGATCATCGCCCGATTCCGC
CACCATAAGGTGTCGGTCGGCACAAGTCCTCGTGCAGGAGAACCGCCTAGTGACGACGCGCCTTTTGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References