Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 2314932..2315454 Replicon chromosome
Accession NZ_CP035088
Organism Pseudomonas viciae strain 11K1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag EPZ47_RS10615 Protein ID WP_135844720.1
Coordinates 2315170..2315454 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag EPZ47_RS10610 Protein ID WP_135844719.1
Coordinates 2314932..2315180 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EPZ47_RS10595 2311356..2312357 + 1002 WP_135844717.1 AAA family ATPase -
EPZ47_RS10600 2312360..2313013 + 654 WP_178084307.1 VWA domain-containing protein -
EPZ47_RS10605 2313219..2314865 + 1647 WP_135844718.1 phospholipase -
EPZ47_RS10610 2314932..2315180 + 249 WP_135844719.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
EPZ47_RS10615 2315170..2315454 + 285 WP_135844720.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EPZ47_RS10620 2315563..2315904 + 342 WP_135844721.1 hypothetical protein -
EPZ47_RS10630 2316329..2317177 + 849 WP_135844722.1 transporter substrate-binding domain-containing protein -
EPZ47_RS10635 2317232..2317894 + 663 WP_135844723.1 amino acid ABC transporter permease -
EPZ47_RS10640 2317904..2318566 + 663 WP_135844724.1 amino acid ABC transporter permease -
EPZ47_RS10645 2318563..2319369 + 807 WP_135844725.1 amino acid ABC transporter ATP-binding protein -
EPZ47_RS10650 2319407..2319796 + 390 WP_135844726.1 RidA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10946.63 Da        Isoelectric Point: 10.2243

>T117180 WP_135844720.1 NZ_CP035088:2315170-2315454 [Pseudomonas viciae]
MTYELEFSDKAWKEWQKLGATLRAQFKKKLEERLENPHVQADRLHGLGNAYKIKLRNAGYRLVYRVVDDLLVVTVIGVGK
RERGQVYDEAAAKR

Download         Length: 285 bp

>T117180 NZ_CP035088:2315170-2315454 [Pseudomonas viciae]
ATGACTTATGAGTTGGAATTTTCCGACAAAGCATGGAAGGAGTGGCAAAAGCTGGGTGCAACTTTAAGGGCACAGTTCAA
GAAAAAGCTGGAGGAGCGGCTTGAGAACCCACATGTCCAGGCGGACCGTCTACACGGACTGGGCAATGCCTATAAGATTA
AGTTGCGTAATGCAGGGTACCGACTGGTCTACCGCGTGGTAGACGATCTGCTGGTCGTTACGGTGATTGGCGTTGGTAAG
CGTGAGCGTGGCCAGGTTTATGACGAGGCGGCTGCCAAGCGGTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8999.39 Da        Isoelectric Point: 4.4000

>AT117180 WP_135844719.1 NZ_CP035088:2314932-2315180 [Pseudomonas viciae]
MTHIVLSQVVASISELKKNPMGTVAAGGGLSVAILNRNEPAFYCVPAKEYEAMMDRLEDMELVALCRERENDSTIKVSLD
DL

Download         Length: 249 bp

>AT117180 NZ_CP035088:2314932-2315180 [Pseudomonas viciae]
ATGACACATATCGTGCTTTCTCAAGTGGTAGCCAGCATTTCCGAACTCAAGAAAAATCCAATGGGCACCGTTGCTGCTGG
TGGAGGATTATCTGTAGCGATCCTCAACCGGAACGAGCCGGCTTTCTATTGTGTTCCTGCCAAGGAATACGAAGCCATGA
TGGACCGGCTTGAGGACATGGAGTTGGTTGCTCTTTGTCGCGAGCGAGAGAATGATTCAACGATCAAGGTTTCTCTCGAT
GACTTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References