Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicA-HicB
Location 283780..284456 Replicon chromosome
Accession NZ_CP035088
Organism Pseudomonas viciae strain 11K1

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag EPZ47_RS01235 Protein ID WP_135843170.1
Coordinates 283780..283962 (+) Length 61 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag EPZ47_RS01240 Protein ID WP_135847931.1
Coordinates 284055..284456 (+) Length 134 a.a.

Genomic Context

EPZ47_RS01220EPZ47_RS01230EPZ47_RS01235EPZ47_RS01240EPZ47_RS01245EPZ47_RS01225EPZ47_RS01250EPZ47_RS01255EPZ47_RS01260EPZ47_RS01265
Location: 279817..281778 (1962 bp)
Type: Others
Protein ID: WP_178084290.1
Location: 282760..283650 (891 bp)
Type: Others
Protein ID: WP_135843169.1
Location: 283780..283962 (183 bp)
Type: Toxin
Protein ID: WP_135843170.1
Location: 284055..284456 (402 bp)
Type: Antitoxin
Protein ID: WP_135847931.1
Location: 284522..285559 (1038 bp)
Type: Others
Protein ID: WP_135843171.1
Location: 281902..282642 (741 bp)
Type: Others
Protein ID: WP_135843168.1
Location: 285616..286458 (843 bp)
Type: Others
Protein ID: WP_135843172.1
Location: 286509..287348 (840 bp)
Type: Others
Protein ID: WP_135843173.1
Location: 287345..288139 (795 bp)
Type: Others
Protein ID: WP_135843174.1
Location: 288165..289142 (978 bp)
Type: Others
Protein ID: WP_135843175.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
EPZ47_RS01220279817..281778+1962WP_178084290.1choline transporter BetT-
EPZ47_RS01225281902..282642-741WP_135843168.1SDR family oxidoreductase-
EPZ47_RS01230282760..283650+891WP_135843169.1LysR family transcriptional regulator-
EPZ47_RS01235283780..283962+183WP_135843170.1type II toxin-antitoxin system HicA family toxinToxin
EPZ47_RS01240284055..284456+402WP_135847931.1type II toxin-antitoxin system HicB family antitoxinAntitoxin
EPZ47_RS01245284522..285559+1038WP_135843171.1L-glyceraldehyde 3-phosphate reductase-
EPZ47_RS01250285616..286458-843WP_135843172.1taurine dioxygenase-
EPZ47_RS01255286509..287348-840WP_135843173.1taurine ABC transporter permease TauC-
EPZ47_RS01260287345..288139-795WP_135843174.1taurine ABC transporter ATP-binding subunit-
EPZ47_RS01265288165..289142-978WP_135843175.1taurine ABC transporter substrate-binding protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(3-59)

Antitoxin

HicB-like antitoxin of toxin-antitoxin system

(3-127)


Sequences

Toxin        


Download         Length: 61 a.a.        Molecular weight: 6871.99 Da        Isoelectric Point: 10.6627

>T117177 WP_135843170.1 NZ_CP035088:283780-283962 [Pseudomonas viciae]
MRSREMIRKIEEDGWYLVAVKGSHHQYKHSFKAGRVTIKHPDADLPKGTINSILKQAGLK

Download         Length: 183 bp

>T117177 NZ_CP035088:283780-283962 [Pseudomonas viciae]
ATGCGAAGTCGGGAAATGATCAGGAAGATCGAAGAGGACGGTTGGTATCTGGTGGCAGTCAAGGGTAGCCATCATCAGTA
CAAGCATTCCTTCAAGGCTGGGAGGGTGACGATCAAACACCCTGACGCCGACCTGCCGAAAGGTACGATTAATAGCATAT
TGAAACAGGCGGGCCTGAAATGA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14625.30 Da        Isoelectric Point: 4.4085

>AT117177 WP_135847931.1 NZ_CP035088:284055-284456 [Pseudomonas viciae]
MKFPVVLHKDADSEYGVTVPDVPGCFSAGSTVGQAFENVKEALSLHYEGLVADGEPLPQIHEIDDHLDNPDYAGGIWGVV
EFDVTPYFGKSVRFNATLPEQLLERIDQTVRRDQRYSSRSGFLAAAALRELSA

Download         Length: 402 bp

>AT117177 NZ_CP035088:284055-284456 [Pseudomonas viciae]
ATGAAATTTCCGGTCGTTCTGCACAAGGATGCCGATTCCGAATACGGAGTGACGGTCCCGGATGTGCCGGGTTGTTTCTC
CGCGGGCAGTACCGTGGGCCAGGCATTCGAAAATGTGAAGGAAGCGCTCTCGTTGCACTATGAAGGGCTGGTAGCCGACG
GCGAGCCGCTGCCGCAGATCCATGAAATTGACGATCATCTCGACAATCCGGATTACGCCGGAGGGATATGGGGTGTGGTT
GAGTTCGATGTCACGCCCTATTTCGGCAAGTCAGTGCGGTTCAACGCCACGCTGCCTGAGCAATTGCTTGAACGCATTGA
TCAAACCGTGCGACGTGATCAGCGCTACAGCTCCCGCTCGGGTTTTTTGGCGGCGGCTGCCTTGCGCGAACTTTCGGCCT
GA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References