Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 468305..468946 Replicon chromosome
Accession NZ_CP035043
Organism Acinetobacter baumannii strain ABUH796

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag EP550_RS02295 Protein ID WP_000607077.1
Coordinates 468557..468946 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag EP550_RS02290 Protein ID WP_011860336.1
Coordinates 468305..468550 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EP550_RS02270 463809..464816 + 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -
EP550_RS02275 464835..465212 + 378 WP_001216380.1 50S ribosomal protein L17 -
EP550_RS02280 465394..466884 + 1491 WP_000415125.1 NAD(P)/FAD-dependent oxidoreductase -
EP550_RS02285 466933..468105 - 1173 WP_001190542.1 acyl-CoA dehydrogenase family protein -
EP550_RS02290 468305..468550 + 246 WP_011860336.1 succinate dehydrogenase assembly factor 2 Antitoxin
EP550_RS02295 468557..468946 + 390 WP_000607077.1 membrane protein Toxin
EP550_RS02300 469716..470801 + 1086 WP_000049106.1 hypothetical protein -
EP550_RS02305 470879..471445 + 567 WP_000651538.1 rhombosortase -
EP550_RS02310 471633..473828 + 2196 WP_064879010.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(6-78)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15552.88 Da        Isoelectric Point: 10.4313

>T117161 WP_000607077.1 NZ_CP035043:468557-468946 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

>T117161 NZ_CP035043:468557-468946 [Acinetobacter baumannii]
TTGATCAACCATTTGAATTTTAAGCTGAAATATAGTCGTTTTTCGATTATATTTCAGTTTTTTATTGGCTTAAGCTTAGC
AGTTCTATTTTATCAATTAATGCCGTTACTATGGTGGTTAGTTGTAATCAGCTTACTATTTATCAGCTTTATTTTCTTTT
TAAAGCGTCCGCAGCTTGCACAAATTGCTTATTTAGATAAAAAACTATGGTCGCTTGCTTATAAGTCACAGAACACCGTT
TCTCGCGTCAAAATTTTAAAAATAATTGATTGTCAGATTTTCATAGTGATCTATTTTGAAGGTCATAAAACACTAACTTC
TATCATTTGGTTTGATCAAATGTCATTAGCAGAGTGGAAAAAGCTTAAAACTTTAGAAAAACTCTATTAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9842.27 Da        Isoelectric Point: 4.9001

>AT117161 WP_011860336.1 NZ_CP035043:468305-468550 [Acinetobacter baumannii]
MTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLKHYVH
G

Download         Length: 246 bp

>AT117161 NZ_CP035043:468305-468550 [Acinetobacter baumannii]
ATGACCTTGGAAGAACGTAAAGTAATCTATCGCGCACGTCGTGGTTTAAAGGAAATTGATGTCTATTTTGACCCTTATGT
GAAAAATTATTATTTAAAGGCAGACCCGGCAGAAAAAGCGTTGTTTGCTGAGTTGGTAGAACAGGAAGACCCTGATTTAC
TAGATTGGTTTATGGAAGTATCAGAACCACCACGTACCGAATTACGTGACTTTATCTATAAATTAAAACACTATGTTCAT
GGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References