Detailed information of TA system TA117113

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RHH(antitoxin)
• Location: 285411..285946
• Replicon: plasmid pRapFH23b
• Accession: NZ_CP035000
• Organism: Rhizobium acidisoli strain FH23

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: CO657_RS26935
• Protein ID: WP_054183896.1
• Coordinates: 285411..285686 (-)
• Length: 92 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: CO657_RS26940
• Protein ID: WP_054183970.1
• Coordinates: 285686..285946 (-)
• Length: 87 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CO657_RS26915	280418..281344	-	927	WP_054183899.1	sugar ABC transporter permease	-
CO657_RS26920	281545..282765	-	1221	WP_054183898.1	sugar ABC transporter substrate-binding protein	-
CO657_RS26925	282815..284136	-	1322	Protein_256	alpha-L-fucosidase	-
CO657_RS26930	284339..285346	+	1008	WP_054183897.1	LacI family transcriptional regulator	-
CO657_RS26935	285411..285686	-	276	WP_054183896.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
CO657_RS26940	285686..285946	-	261	WP_054183970.1	ribbon-helix-helix domain-containing protein	Antitoxin
CO657_RS26945	286145..286873	+	729	WP_054183895.1	FadR family transcriptional regulator	-
CO657_RS26950	287159..288172	+	1014	WP_054183969.1	ABC transporter substrate-binding protein	-
CO657_RS26955	288268..289086	+	819	WP_054183894.1	ABC transporter ATP-binding protein	-
CO657_RS26960	289099..289980	+	882	WP_054183893.1	ABC transporter permease	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Mobilizable plasmid	-	-	1..701880	701880

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-90)

Antitoxin

• Ribbon-helix-helix protein, CopG (6-43)

Sequences

Toxin

Protein

• Length: 92 a.a.
• Molecular weight: 10877.61 Da
• Isoelectric Point: 9.9706

>T117113 WP_054183896.1 NZ_CP035000:c285686-285411 [Rhizobium acidisoli]
MELKWTSKAVGDIDRLYAFLAPVNRQVAVRTVQALTAAPLRLLEQPRLGERLEEFDPREVRRILVGRYELRYEIQQSVIY
VLRLWHTREDR

Nucleotide

• Length: 276 bp

>T117113 NZ_CP035000:c285686-285411 [Rhizobium acidisoli]
ATGGAACTTAAGTGGACGAGCAAAGCGGTCGGGGACATTGATCGCCTTTATGCCTTTCTCGCGCCGGTTAATCGACAGGT
GGCGGTCCGGACCGTGCAGGCATTGACGGCTGCCCCTCTACGGCTGCTTGAGCAGCCGCGTCTTGGTGAACGGCTGGAGG
AGTTCGATCCTCGGGAGGTTCGCCGCATTCTCGTTGGACGGTATGAACTGCGTTACGAAATCCAGCAGTCGGTCATCTAT
GTATTGCGGCTCTGGCATACGCGAGAAGACCGGTAA

Antitoxin

Protein

• Length: 87 a.a.
• Molecular weight: 9711.04 Da
• Isoelectric Point: 5.1358

>AT117113 WP_054183970.1 NZ_CP035000:c285946-285686 [Rhizobium acidisoli]
METKVLTAHVPLPLAQKVDQLAARLERSRGWIVKQALTAWIDQEEERRRLTLEALADVEEGKVVDHQSVRAWADSLDSDA
PVSLPR

Nucleotide

• Length: 261 bp

>AT117113 NZ_CP035000:c285946-285686 [Rhizobium acidisoli]
ATGGAAACCAAAGTGCTGACCGCGCATGTCCCTCTGCCCCTTGCACAGAAGGTCGATCAACTCGCCGCGAGGCTTGAGCG
CTCGCGCGGCTGGATCGTCAAGCAGGCGCTGACGGCGTGGATCGACCAGGAGGAGGAGCGTCGCCGTTTGACGCTGGAGG
CTCTGGCTGATGTGGAGGAAGGCAAGGTGGTCGATCACCAGTCCGTCCGGGCTTGGGCCGATAGTCTCGATAGTGACGCG
CCGGTTTCTTTGCCTCGGTAA