Detailed information of TA system TA117109

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): pasABC/RelE-HTH
• Location: 702872..703349
• Replicon: chromosome
• Accession: NZ_CP034998
• Organism: Rhizobium acidisoli strain FH23

Toxin (Protein)

• Gene name: pasB
• Uniprot ID: -
• Locus tag: CO657_RS03440
• Protein ID: WP_054181527.1
• Coordinates: 703080..703349 (+)
• Length: 90 a.a.

Antitoxin (Protein)

• Gene name: pasA
• Uniprot ID: -
• Locus tag: CO657_RS03435
• Protein ID: WP_054181526.1
• Coordinates: 702872..703096 (+)
• Length: 75 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CO657_RS03410	698569..699711	+	1143	WP_003588031.1	site-specific DNA-methyltransferase	-
CO657_RS03415	699883..700248	-	366	WP_054181523.1	nuclear transport factor 2 family protein	-
CO657_RS03420	700253..700876	-	624	WP_054181524.1	HAD family phosphatase	-
CO657_RS03425	700873..701970	-	1098	WP_054181525.1	A/G-specific adenine glycosylase	-
CO657_RS03430	702079..702576	+	498	WP_054181918.1	DUF721 domain-containing protein	-
CO657_RS03435	702872..703096	+	225	WP_054181526.1	TraY domain-containing protein	Antitoxin
CO657_RS03440	703080..703349	+	270	WP_054181527.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
CO657_RS03445	703499..704275	+	777	WP_054181528.1	DsbA family protein	-
CO657_RS03455	704555..708016	+	3462	WP_054181529.1	chromosome segregation protein SMC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-88)

Antitoxin

• Relaxosome protein TraY (4-49)

Sequences

Toxin

Protein

• Length: 90 a.a.
• Molecular weight: 10494.04 Da
• Isoelectric Point: 10.0802

>T117109 WP_054181527.1 NZ_CP034998:703080-703349 [Rhizobium acidisoli]
MVWRIEFHRAAERELEKLGHETARRILRFLNDRVARLDDPRSIGDALKGSELGDFWKYRVGDYRVIANIDDGAVLILIVR
IGNRRDVYR

Nucleotide

• Length: 270 bp

>T117109 NZ_CP034998:703080-703349 [Rhizobium acidisoli]
ATGGTTTGGAGAATTGAGTTTCACCGAGCAGCCGAGCGTGAGCTTGAGAAGCTTGGGCATGAGACGGCTCGCCGAATACT
CCGATTTCTGAATGATCGCGTTGCAAGGTTGGACGATCCGCGATCCATCGGAGACGCGCTTAAGGGGTCTGAACTCGGGG
ATTTCTGGAAATATCGCGTCGGGGACTATCGAGTGATCGCAAACATTGACGATGGGGCGGTGCTGATCCTCATCGTGCGG
ATTGGCAACCGCCGCGATGTCTATCGATGA

Antitoxin

Protein

• Length: 75 a.a.
• Molecular weight: 8593.74 Da
• Isoelectric Point: 4.8782

>AT117109 WP_054181526.1 NZ_CP034998:702872-703096 [Rhizobium acidisoli]
MLALRLPSDIEARLDELSRRTGRSKSFYARQAILEHLDDLEDIYLAEKRLEELRRGESDTVPLAELMARHGLEN

Nucleotide

• Length: 225 bp

>AT117109 NZ_CP034998:702872-703096 [Rhizobium acidisoli]
ATGCTGGCCTTGCGATTGCCATCTGATATCGAAGCACGGCTCGATGAGCTTTCCAGGCGCACGGGCCGCAGCAAGAGCTT
CTATGCGCGTCAAGCCATCCTCGAACATCTCGATGATCTCGAGGATATCTATCTCGCCGAGAAACGCCTGGAAGAACTTC
GTCGGGGTGAGAGCGATACCGTGCCGTTGGCCGAGCTGATGGCGCGTCATGGTTTGGAGAATTGA