Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1989023..1989294 Replicon chromosome
Accession NZ_CP034966
Organism Escherichia coli strain WCHEC020032

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1989153..1989256 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1989023..1989294 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C7V17_RS11490 1985578..1986240 - 663 WP_000944256.1 exodeoxyribonuclease X -
C7V17_RS11495 1986264..1986920 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
C7V17_RS11500 1987022..1987252 - 231 WP_000916763.1 DNA polymerase III subunit theta -
C7V17_RS11505 1987391..1987765 + 375 WP_000204699.1 CopC domain-containing protein YobA -
C7V17_RS11510 1987769..1988641 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
C7V17_RS11515 1988654..1988995 + 342 WP_000976492.1 YebY family protein -
- 1989023..1989294 - 272 - - Antitoxin
- 1989153..1989256 + 104 - - Toxin
C7V17_RS11520 1989391..1990047 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
C7V17_RS11525 1990048..1990239 - 192 WP_001296140.1 YebW family protein -
C7V17_RS11530 1990344..1990580 - 237 WP_001295499.1 DUF1480 family protein -
C7V17_RS11535 1990698..1992137 - 1440 WP_000057023.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T117093 NZ_CP034966:1989153-1989256 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT117093 NZ_CP034966:c1989294-1989023 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References