Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 4819591..4820126 Replicon chromosome
Accession NZ_CP034938
Organism Pectobacterium odoriferum strain JK2.1

Toxin (Protein)


Gene name relE Uniprot ID A0A094RUX3
Locus tag EO763_RS21745 Protein ID WP_044207310.1
Coordinates 4819839..4820126 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q6DB37
Locus tag EO763_RS21740 Protein ID WP_010281712.1
Coordinates 4819591..4819842 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EO763_RS21705 4814809..4815135 + 327 WP_208851970.1 helix-turn-helix domain-containing protein -
EO763_RS21710 4815120..4815434 + 315 WP_039490249.1 HipA N-terminal domain-containing protein -
EO763_RS21715 4815431..4816471 + 1041 WP_161530185.1 HipA domain-containing protein -
EO763_RS21720 4816532..4816666 - 135 Protein_4254 LysE family translocator -
EO763_RS21725 4816865..4817569 + 705 WP_161530186.1 SMI1/KNR4 family protein -
EO763_RS21730 4817638..4818393 + 756 WP_161530187.1 thiol:disulfide interchange protein DsbG -
EO763_RS21735 4818428..4819333 - 906 WP_161530188.1 siderophore-interacting protein -
EO763_RS21740 4819591..4819842 + 252 WP_010281712.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
EO763_RS21745 4819839..4820126 + 288 WP_044207310.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EO763_RS21750 4820228..4821580 - 1353 WP_161530189.1 glutathione-disulfide reductase -
EO763_RS21755 4821709..4822551 - 843 WP_103160431.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
EO763_RS21760 4822770..4823498 + 729 WP_161530190.1 DUF1266 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11060.17 Da        Isoelectric Point: 10.4703

>T117007 WP_044207310.1 NZ_CP034938:4819839-4820126 [Pectobacterium odoriferum]
MSYRVKFREDALKEWLKLDKAIQQQFAKKLKKCCENPHIPAAKLRGMKDCYKIKLRASGFRLVYEVIDDVLVIAVVAVGK
RERSGVYNLASERMR

Download         Length: 288 bp

>T117007 NZ_CP034938:4819839-4820126 [Pectobacterium odoriferum]
ATGAGTTATCGCGTCAAATTCAGGGAAGATGCGCTAAAAGAATGGCTCAAACTCGATAAAGCTATCCAACAACAATTTGC
CAAAAAACTAAAAAAATGCTGCGAAAATCCCCATATTCCTGCGGCAAAGTTACGGGGAATGAAGGATTGCTACAAAATAA
AGCTCCGAGCATCAGGCTTTCGTTTGGTTTATGAGGTTATTGACGACGTATTGGTTATCGCCGTGGTAGCGGTAGGCAAA
CGTGAGCGCAGCGGCGTCTATAATCTGGCAAGTGAGCGGATGAGGTAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9117.47 Da        Isoelectric Point: 4.0637

>AT117007 WP_010281712.1 NZ_CP034938:4819591-4819842 [Pectobacterium odoriferum]
MPNIILSDTSASVSELKKNPMATVNAGDGLPVAILNRNQPAFYCIPADLYEKMLDALDDQELVKLIGERKNQPLVDVDLD
SFL

Download         Length: 252 bp

>AT117007 NZ_CP034938:4819591-4819842 [Pectobacterium odoriferum]
ATGCCAAATATTATATTAAGCGATACCAGTGCTAGCGTCAGTGAACTGAAAAAGAACCCAATGGCGACGGTCAATGCTGG
TGATGGCCTGCCTGTCGCTATCTTGAACCGCAACCAACCTGCGTTTTATTGCATTCCTGCGGATCTCTACGAAAAAATGC
TGGATGCGCTGGACGATCAGGAGCTGGTTAAGCTGATCGGTGAACGTAAAAACCAGCCGCTGGTTGACGTGGATTTGGAT
AGTTTCCTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A094RUX3

Antitoxin

Source ID Structure
AlphaFold DB A0A0M2EZP0

References