Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 1702072..1702625 Replicon chromosome
Accession NZ_CP034938
Organism Pectobacterium odoriferum strain JK2.1

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag EO763_RS07550 Protein ID WP_161528562.1
Coordinates 1702311..1702625 (+) Length 105 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag EO763_RS07545 Protein ID WP_161528561.1
Coordinates 1702072..1702308 (+) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EO763_RS07525 1697116..1697709 - 594 WP_161528558.1 hypothetical protein -
EO763_RS07530 1697711..1699138 - 1428 WP_161528559.1 AAA family ATPase -
EO763_RS07535 1699561..1700526 - 966 WP_039494396.1 IS110 family transposase -
EO763_RS07540 1700808..1701752 + 945 WP_161528560.1 DUF1738 domain-containing protein -
EO763_RS07545 1702072..1702308 + 237 WP_161528561.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
EO763_RS07550 1702311..1702625 + 315 WP_161528562.1 CcdB family protein Toxin
EO763_RS07555 1702659..1703411 - 753 WP_161528563.1 molybdopterin-guanine dinucleotide biosynthesis protein MobC -
EO763_RS07560 1703420..1705155 - 1736 Protein_1472 type IV secretory system conjugative DNA transfer family protein -
EO763_RS07565 1705950..1706252 - 303 WP_161528564.1 conjugal transfer protein -
EO763_RS07570 1706296..1707312 - 1017 WP_161528565.1 P-type DNA transfer ATPase VirB11 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 1690845..1725360 34515
- flank IS/Tn - - 1699561..1700526 965


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-103)

Antitoxin

Post-segregation antitoxin CcdA

(9-78)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11510.48 Da        Isoelectric Point: 6.9727

>T117001 WP_161528562.1 NZ_CP034938:1702311-1702625 [Pectobacterium odoriferum]
MQFTVYGNTGKSVVYPLLLDVTSDIIGQLNRRIVIPLLPIEKYPAGRRPDRLVPVVMLTDGKEYAVMTHELASIPVQALG
AVFCDASQYRTQVKAAIDFLIDGF

Download         Length: 315 bp

>T117001 NZ_CP034938:1702311-1702625 [Pectobacterium odoriferum]
ATGCAATTCACTGTATACGGTAATACCGGGAAAAGCGTCGTTTACCCGCTGTTGCTCGATGTCACGAGCGATATTATCGG
GCAATTGAATCGTCGGATAGTGATCCCATTGCTCCCTATTGAAAAGTATCCGGCAGGTCGCCGACCGGATCGCCTTGTCC
CCGTCGTCATGCTGACGGACGGCAAAGAATACGCCGTAATGACCCACGAGCTGGCAAGTATCCCTGTCCAGGCTCTGGGG
GCGGTGTTTTGTGATGCATCGCAGTACCGCACTCAGGTAAAGGCCGCAATAGACTTCCTCATCGACGGATTCTGA

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8971.97 Da        Isoelectric Point: 5.6999

>AT117001 WP_161528561.1 NZ_CP034938:1702072-1702308 [Pectobacterium odoriferum]
MTGKQRNTQSVTMTVERALLVRAREAGINLSATLTTALDAELRSHEAKKWQEENREALAALNRFHDEQDCFSDEYRTF

Download         Length: 237 bp

>AT117001 NZ_CP034938:1702072-1702308 [Pectobacterium odoriferum]
ATGACCGGGAAACAACGCAACACGCAGAGCGTGACCATGACAGTAGAGCGTGCCTTACTGGTAAGAGCGCGTGAGGCGGG
CATTAATCTGAGTGCTACCCTGACAACTGCCCTGGATGCAGAGCTTCGCTCTCATGAAGCGAAAAAATGGCAGGAAGAAA
ACAGGGAGGCTCTCGCAGCACTAAATCGTTTTCATGATGAGCAGGATTGTTTCAGCGATGAATACAGGACGTTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References