Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | PP_4151-4152/excise(antitoxin) |
| Location | 1195360..1196396 | Replicon | chromosome |
| Accession | NZ_CP034938 | ||
| Organism | Pectobacterium odoriferum strain JK2.1 | ||
Toxin (Protein)
| Gene name | PP_4152 | Uniprot ID | - |
| Locus tag | EO763_RS05345 | Protein ID | WP_161528326.1 |
| Coordinates | 1195821..1196396 (+) | Length | 192 a.a. |
Antitoxin (Protein)
| Gene name | PP_4151 | Uniprot ID | A0A6P1RQC6 |
| Locus tag | EO763_RS05340 | Protein ID | WP_039497370.1 |
| Coordinates | 1195360..1195821 (+) | Length | 154 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EO763_RS05320 | 1190422..1190954 | + | 533 | Protein_1038 | RNA pyrophosphohydrolase | - |
| EO763_RS05325 | 1190967..1193213 | + | 2247 | WP_161528325.1 | phosphoenolpyruvate--protein phosphotransferase | - |
| EO763_RS05330 | 1193440..1194306 | + | 867 | WP_039490611.1 | prolipoprotein diacylglyceryl transferase | - |
| EO763_RS05335 | 1194343..1195137 | + | 795 | WP_010299697.1 | thymidylate synthase | - |
| EO763_RS05340 | 1195360..1195821 | + | 462 | WP_039497370.1 | helix-turn-helix domain-containing protein | Antitoxin |
| EO763_RS05345 | 1195821..1196396 | + | 576 | WP_161528326.1 | PIN domain-containing protein | Toxin |
| EO763_RS05350 | 1196576..1197079 | + | 504 | WP_161528327.1 | prepilin peptidase-dependent protein | - |
| EO763_RS05355 | 1197073..1197684 | + | 612 | WP_161528328.1 | prepilin peptidase-dependent protein | - |
| EO763_RS05360 | 1197681..1198136 | + | 456 | WP_208851985.1 | DUF2509 family protein | - |
| EO763_RS05365 | 1198123..1198518 | + | 396 | WP_161530343.1 | prepilin-type N-terminal cleavage/methylation domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 192 a.a. Molecular weight: 21494.88 Da Isoelectric Point: 4.8598
>T116999 WP_161528326.1 NZ_CP034938:1195821-1196396 [Pectobacterium odoriferum]
MNHSPYPVVLDACVIYPSLLRDLLMHLGLTGLYQPKWTAKIQEEWQRNLLLNNADVTIDKLRNIEHLMNKALPDANVTGY
EQLISALVLPDADDRHVLAAAIRANAEVIVTANLKDFPATALLEFGVEAMHPDEFIADLFDLNSALVLKAVRTSRTAFRK
PPFDVDEYLDCLLRQGLPMTVKELDAYRSLI
MNHSPYPVVLDACVIYPSLLRDLLMHLGLTGLYQPKWTAKIQEEWQRNLLLNNADVTIDKLRNIEHLMNKALPDANVTGY
EQLISALVLPDADDRHVLAAAIRANAEVIVTANLKDFPATALLEFGVEAMHPDEFIADLFDLNSALVLKAVRTSRTAFRK
PPFDVDEYLDCLLRQGLPMTVKELDAYRSLI
Download Length: 576 bp
>T116999 NZ_CP034938:1195821-1196396 [Pectobacterium odoriferum]
ATGAATCATTCACCTTATCCCGTCGTACTTGATGCATGTGTAATCTATCCATCTTTGCTACGGGATTTGCTCATGCATCT
TGGTTTAACGGGGTTATATCAGCCAAAATGGACGGCAAAAATTCAGGAAGAGTGGCAGCGAAATTTGTTGCTAAATAACG
CTGACGTAACGATAGATAAGCTCAGAAATATTGAGCATCTGATGAATAAGGCATTACCTGATGCCAATGTGACTGGATAC
GAGCAACTTATCTCTGCTCTGGTTTTACCTGATGCGGATGATCGACATGTATTGGCAGCGGCGATACGCGCTAATGCAGA
AGTTATCGTCACTGCGAATCTGAAAGACTTTCCTGCAACGGCACTTTTGGAATTTGGAGTGGAAGCCATGCATCCAGACG
AATTCATTGCCGATTTATTTGATCTCAATTCTGCTCTGGTGCTTAAAGCTGTTCGCACTTCGCGCACTGCCTTCAGAAAG
CCTCCGTTTGATGTAGACGAATATCTGGATTGTCTCCTGCGTCAGGGGTTACCAATGACGGTAAAAGAACTGGACGCGTA
TCGATCGCTGATTTAA
ATGAATCATTCACCTTATCCCGTCGTACTTGATGCATGTGTAATCTATCCATCTTTGCTACGGGATTTGCTCATGCATCT
TGGTTTAACGGGGTTATATCAGCCAAAATGGACGGCAAAAATTCAGGAAGAGTGGCAGCGAAATTTGTTGCTAAATAACG
CTGACGTAACGATAGATAAGCTCAGAAATATTGAGCATCTGATGAATAAGGCATTACCTGATGCCAATGTGACTGGATAC
GAGCAACTTATCTCTGCTCTGGTTTTACCTGATGCGGATGATCGACATGTATTGGCAGCGGCGATACGCGCTAATGCAGA
AGTTATCGTCACTGCGAATCTGAAAGACTTTCCTGCAACGGCACTTTTGGAATTTGGAGTGGAAGCCATGCATCCAGACG
AATTCATTGCCGATTTATTTGATCTCAATTCTGCTCTGGTGCTTAAAGCTGTTCGCACTTCGCGCACTGCCTTCAGAAAG
CCTCCGTTTGATGTAGACGAATATCTGGATTGTCTCCTGCGTCAGGGGTTACCAATGACGGTAAAAGAACTGGACGCGTA
TCGATCGCTGATTTAA
Antitoxin
Download Length: 154 a.a. Molecular weight: 17243.76 Da Isoelectric Point: 6.2253
>AT116999 WP_039497370.1 NZ_CP034938:1195360-1195821 [Pectobacterium odoriferum]
MKNTPLNSLSLPAPKEMEAAIRGQRQLATYLSTKLETQEISIQDAHDIAHRIELPTSALTLLMSILGELAAGNAVQIVPV
QAELTTQEAANILNVSRPHMVKLLEEGHLPFHKTGRHRRVLFADLMQYKEQRENESMQAMQELTDRSQELGFY
MKNTPLNSLSLPAPKEMEAAIRGQRQLATYLSTKLETQEISIQDAHDIAHRIELPTSALTLLMSILGELAAGNAVQIVPV
QAELTTQEAANILNVSRPHMVKLLEEGHLPFHKTGRHRRVLFADLMQYKEQRENESMQAMQELTDRSQELGFY
Download Length: 462 bp
>AT116999 NZ_CP034938:1195360-1195821 [Pectobacterium odoriferum]
ATGAAAAATACTCCTCTAAATAGTTTGAGCCTTCCGGCTCCAAAAGAAATGGAGGCCGCTATCCGTGGACAAAGGCAGCT
TGCAACCTACCTGTCTACGAAGCTGGAAACACAGGAAATTTCGATTCAGGATGCGCATGACATTGCCCATCGGATCGAGT
TGCCTACCTCGGCACTCACGCTTCTGATGAGCATCCTTGGCGAACTGGCTGCGGGCAACGCTGTCCAGATTGTCCCTGTG
CAAGCTGAGTTAACGACACAAGAAGCGGCAAATATTCTGAATGTTTCACGGCCACATATGGTGAAGCTTTTGGAAGAAGG
GCATCTTCCTTTCCATAAAACAGGTCGTCATCGCCGCGTGCTTTTTGCTGATTTGATGCAATACAAAGAACAGCGTGAAA
ATGAAAGTATGCAAGCCATGCAGGAGCTGACAGATCGAAGTCAGGAGCTCGGGTTTTACTAA
ATGAAAAATACTCCTCTAAATAGTTTGAGCCTTCCGGCTCCAAAAGAAATGGAGGCCGCTATCCGTGGACAAAGGCAGCT
TGCAACCTACCTGTCTACGAAGCTGGAAACACAGGAAATTTCGATTCAGGATGCGCATGACATTGCCCATCGGATCGAGT
TGCCTACCTCGGCACTCACGCTTCTGATGAGCATCCTTGGCGAACTGGCTGCGGGCAACGCTGTCCAGATTGTCCCTGTG
CAAGCTGAGTTAACGACACAAGAAGCGGCAAATATTCTGAATGTTTCACGGCCACATATGGTGAAGCTTTTGGAAGAAGG
GCATCTTCCTTTCCATAAAACAGGTCGTCATCGCCGCGTGCTTTTTGCTGATTTGATGCAATACAAAGAACAGCGTGAAA
ATGAAAGTATGCAAGCCATGCAGGAGCTGACAGATCGAAGTCAGGAGCTCGGGTTTTACTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|