Detailed information of TA system TA116998

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/Cpta(toxin)
• Location: 759817..760477
• Replicon: chromosome
• Accession: NZ_CP034938
• Organism: Pectobacterium odoriferum strain JK2.1

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: EO763_RS03420
• Protein ID: WP_161528096.1
• Coordinates: 760064..760477 (+)
• Length: 138 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: A0A1V2R9A9
• Locus tag: EO763_RS03415
• Protein ID: WP_039355397.1
• Coordinates: 759817..760083 (+)
• Length: 89 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EO763_RS03395	755932..756936	-	1005	WP_161528092.1	substrate-binding domain-containing protein	-
EO763_RS03400	756991..757599	-	609	WP_161528093.1	HD domain-containing protein	-
EO763_RS03405	757878..758525	+	648	WP_161528094.1	hemolysin III family protein	-
EO763_RS03410	758580..759581	-	1002	WP_161528095.1	tRNA-modifying protein YgfZ	-
EO763_RS03415	759817..760083	+	267	WP_039355397.1	FAD assembly factor SdhE	Antitoxin
EO763_RS03420	760064..760477	+	414	WP_161528096.1	protein YgfX	Toxin
EO763_RS03425	760546..761481	+	936	WP_161528097.1	23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF	-
EO763_RS03430	761562..762080	-	519	WP_044204035.1	flavodoxin FldB	-
EO763_RS03435	762242..763570	-	1329	WP_161528098.1	MHS family MFS transporter	-
EO763_RS03440	763890..764789	+	900	WP_161528099.1	site-specific tyrosine recombinase XerD	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Inner membrane protein YgfX (2-132)

Antitoxin

• Flavinator of succinate dehydrogenase (8-79)

Sequences

Toxin

Protein

• Length: 138 a.a.
• Molecular weight: 16358.32 Da
• Isoelectric Point: 11.0239

>T116998 WP_161528096.1 NZ_CP034938:760064-760477 [Pectobacterium odoriferum]
VAQWRCDLRVSWRMQLLSLVVHGLLVLFILLAPWPDGYAWLWLCLVTMVMFGFIRSQRNIKSRQGEIVLLSETTLNWRQQ
EWQIVKRPWLLKNGVLLSLQAVNAKDKQQLWLASDSMGNDEWRHLRQILLQQKHWAR

Nucleotide

• Length: 414 bp

>T116998 NZ_CP034938:760064-760477 [Pectobacterium odoriferum]
GTGGCCCAGTGGCGATGTGACCTTCGCGTTTCCTGGCGCATGCAGTTGCTGTCATTGGTGGTGCATGGCCTCTTAGTATT
ATTCATTCTGCTGGCACCGTGGCCGGACGGCTATGCGTGGCTATGGCTATGCCTGGTCACGATGGTGATGTTCGGTTTTA
TCCGTAGCCAAAGGAATATTAAATCCCGACAGGGGGAAATCGTTCTGCTCAGCGAAACGACCCTGAACTGGCGGCAGCAG
GAATGGCAAATCGTTAAGCGACCGTGGCTGCTGAAGAATGGCGTGTTGCTGTCATTGCAGGCGGTTAACGCTAAAGACAA
GCAACAGCTGTGGCTGGCATCGGACAGCATGGGCAATGACGAATGGCGTCACTTGCGTCAGATTCTTTTGCAGCAGAAAC
ACTGGGCAAGATAG

Antitoxin

Protein

• Length: 89 a.a.
• Molecular weight: 10506.99 Da
• Isoelectric Point: 6.2223

>AT116998 WP_039355397.1 NZ_CP034938:759817-760083 [Pectobacterium odoriferum]
MEIDNKSRIHWACRRGMRELDIAIMPFFEHDYDTLNDTDKRTFVRLLQSDDPDLFNWLMNHGEPKDGELKRMISLIQTRN
KDRGPVAM

Nucleotide

• Length: 267 bp

>AT116998 NZ_CP034938:759817-760083 [Pectobacterium odoriferum]
ATGGAAATCGATAATAAATCACGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAATTGGATATCGCGATCATGCCGTT
TTTTGAGCATGACTATGACACACTGAATGACACTGATAAGCGTACGTTTGTACGTTTGTTACAAAGCGACGATCCCGATT
TATTCAACTGGCTGATGAACCACGGTGAACCGAAGGACGGAGAGCTGAAACGCATGATTTCCCTTATTCAGACGCGAAAT
AAAGACCGTGGCCCAGTGGCGATGTGA

Structures

Antitoxin

• AlphaFold DB: A0A1V2R9A9