Detailed information of TA system TA116997

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 539174..539757
• Replicon: chromosome
• Accession: NZ_CP034938
• Organism: Pectobacterium odoriferum strain JK2.1

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: EO763_RS02415
• Protein ID: WP_161527972.1
• Coordinates: 539452..539757 (+)
• Length: 102 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A7V8PT23
• Locus tag: EO763_RS02410
• Protein ID: WP_010296210.1
• Coordinates: 539174..539464 (+)
• Length: 97 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EO763_RS02390	534308..535570	-	1263	WP_161527970.1	L-rhamnose isomerase	-
EO763_RS02395	535567..537057	-	1491	WP_161527971.1	rhamnulokinase	-
EO763_RS02400	537394..538233	+	840	WP_044203767.1	HTH-type transcriptional activator RhaS	-
EO763_RS02405	538258..539112	+	855	WP_040031929.1	helix-turn-helix domain-containing protein	-
EO763_RS02410	539174..539464	+	291	WP_010296210.1	ribbon-helix-helix protein, CopG family	Antitoxin
EO763_RS02415	539452..539757	+	306	WP_161527972.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
EO763_RS02420	539876..541573	-	1698	WP_161527973.1	ABC transporter ATP-binding protein	-
EO763_RS02425	541570..542436	-	867	WP_161527974.1	ABC transporter permease	-
EO763_RS02430	542429..543388	-	960	WP_161527975.1	ABC transporter permease	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-96)

Antitoxin

• Ribbon-helix-helix protein, CopG (9-46)

Sequences

Toxin

Protein

• Length: 102 a.a.
• Molecular weight: 11592.48 Da
• Isoelectric Point: 9.8325

>T116997 WP_161527972.1 NZ_CP034938:539452-539757 [Pectobacterium odoriferum]
MPQVIVSERARRDLQRLQDFLKNKNALAAKKAAEVLIRGIRQLEALPNIGRPVEHLPLEYQELVIEFGSSGYVMLYRHDE
LTGRVVILTVKHQKEAGYQNL

Nucleotide

• Length: 306 bp

>T116997 NZ_CP034938:539452-539757 [Pectobacterium odoriferum]
ATGCCACAAGTGATCGTTTCAGAACGCGCGAGGCGTGATTTGCAGCGTCTACAGGATTTTCTAAAAAACAAAAATGCGCT
GGCCGCGAAAAAGGCCGCTGAAGTTTTGATTCGGGGCATTCGTCAGTTAGAAGCGCTGCCGAATATCGGACGACCCGTGG
AACATCTTCCCCTTGAATATCAGGAACTGGTGATCGAGTTCGGCAGCAGTGGGTATGTGATGCTTTACCGTCACGATGAA
CTGACCGGCAGAGTAGTGATACTGACCGTTAAACATCAAAAAGAAGCCGGTTATCAAAACCTGTAA

Antitoxin

Protein

• Length: 97 a.a.
• Molecular weight: 11064.13 Da
• Isoelectric Point: 4.7692

>AT116997 WP_010296210.1 NZ_CP034938:539174-539464 [Pectobacterium odoriferum]
MADTTRQTTTLRIDQDIKERLKTLADDRNSSAHALMLEAIAEYVEREEKRSQYRKEALAAWEDYQDTGKHITADETVTWL
ESWGSGHEQDAPACHK

Nucleotide

• Length: 291 bp

>AT116997 NZ_CP034938:539174-539464 [Pectobacterium odoriferum]
ATGGCTGATACCACACGTCAAACCACGACGCTGCGCATCGATCAGGACATTAAAGAACGACTGAAAACGCTGGCCGATGA
CCGCAACAGCTCTGCCCATGCGCTAATGTTGGAAGCGATTGCCGAATACGTTGAGCGGGAAGAAAAACGCAGTCAGTACC
GTAAAGAGGCGTTGGCCGCGTGGGAAGACTATCAGGACACTGGCAAACATATCACCGCAGATGAGACCGTCACTTGGTTA
GAATCCTGGGGTTCTGGACATGAACAGGATGCGCCTGCATGCCACAAGTGA

Structures

Antitoxin

• AlphaFold DB: A0A7V8PT23