Detailed information of TA system TA116992

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE-HTH_XRE
• Location: 130842..131547
• Replicon: chromosome
• Accession: NZ_CP034938
• Organism: Pectobacterium odoriferum strain JK2.1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: EO763_RS00555
• Protein ID: WP_161527762.1
• Coordinates: 131122..131547 (-)
• Length: 142 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: EO763_RS00550
• Protein ID: WP_103943792.1
• Coordinates: 130842..131141 (-)
• Length: 100 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EO763_RS00525	126081..126863	-	783	WP_039491933.1	hydroxypyruvate isomerase family protein	-
EO763_RS00530	126882..127538	-	657	WP_161527760.1	aldolase	-
EO763_RS00535	127535..128809	-	1275	WP_161527761.1	four-carbon acid sugar kinase family protein	-
EO763_RS00540	128806..129720	-	915	WP_014917036.1	NAD(P)-dependent oxidoreductase	-
EO763_RS00545	130059..130820	+	762	WP_103862321.1	DeoR/GlpR family DNA-binding transcription regulator	-
EO763_RS00550	130842..131141	-	300	WP_103943792.1	helix-turn-helix domain-containing protein	Antitoxin
EO763_RS00555	131122..131547	-	426	WP_161527762.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
EO763_RS00565	132044..132739	+	696	WP_161527763.1	hypothetical protein	-
EO763_RS00570	132741..133157	+	417	WP_161530309.1	hypothetical protein	-
EO763_RS00575	133268..133546	+	279	WP_044204184.1	DUF1778 domain-containing protein	-
EO763_RS00580	133537..134016	+	480	Protein_113	GNAT family N-acetyltransferase	-
EO763_RS00585	134149..135483	+	1335	WP_010303220.1	sn-glycerol-3-phosphate ABC transporter substrate-binding protein UgpB	-
EO763_RS00590	135556..136443	+	888	WP_103157850.1	sn-glycerol-3-phosphate ABC transporter permease UgpA	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-2 (3-123)

Antitoxin

• Cro/C1-type helix-turn-helix domain (46-86)

Sequences

Toxin

Protein

• Length: 142 a.a.
• Molecular weight: 15559.01 Da
• Isoelectric Point: 9.1085

>T116992 WP_161527762.1 NZ_CP034938:c131547-131122 [Pectobacterium odoriferum]
VAVYTTKLFDKKLRSEILSDGYLCEIAHEVMNGRFEGDLGGGVIKKRIALNAGKSVGARTIIFFKLGSNLFFADGWKKNQ
VRKGVKEIQDDELAVYKDIAGDLLQLTVQQIAQLVKVKELREVECDGCKDERAAGNGKKPA

Nucleotide

• Length: 426 bp

>T116992 NZ_CP034938:c131547-131122 [Pectobacterium odoriferum]
GTGGCGGTATACACGACAAAGCTCTTCGATAAAAAACTAAGAAGCGAAATACTTTCAGATGGTTACCTTTGTGAGATTGC
TCATGAGGTAATGAATGGTCGCTTTGAGGGTGACCTTGGCGGTGGTGTGATTAAGAAACGAATCGCATTGAATGCCGGAA
AGAGTGTAGGAGCCAGAACTATCATCTTTTTCAAACTGGGCTCTAATCTATTTTTTGCCGATGGATGGAAAAAAAATCAG
GTCAGGAAAGGCGTTAAAGAAATTCAGGATGATGAGCTGGCTGTTTATAAAGACATTGCTGGTGACCTACTTCAACTCAC
CGTTCAACAAATAGCTCAATTGGTAAAAGTGAAAGAACTACGAGAGGTGGAATGCGATGGCTGCAAAGATGAAAGAGCTG
CAGGAAATGGCAAAAAGCCTGCATGA

Antitoxin

Protein

• Length: 100 a.a.
• Molecular weight: 11209.74 Da
• Isoelectric Point: 10.0902

>AT116992 WP_103943792.1 NZ_CP034938:c131141-130842 [Pectobacterium odoriferum]
MAKSLHEHGGITDTTMERINNRVAAREFRERIEQAHAMSGAEIQNMRSRYKMSQSSLAYALNMSVESVSKWERNEKKPSG
AALRLLNIINEKGLDIFAS

Nucleotide

• Length: 300 bp

>AT116992 NZ_CP034938:c131141-130842 [Pectobacterium odoriferum]
ATGGCAAAAAGCCTGCATGAACACGGGGGTATCACTGATACCACAATGGAACGCATCAATAATCGGGTTGCAGCACGGGA
ATTCCGTGAACGCATCGAGCAAGCTCACGCAATGAGCGGTGCAGAAATTCAGAACATGCGCTCCCGTTATAAAATGTCGC
AATCTTCTTTAGCTTACGCTCTCAATATGTCCGTTGAGAGCGTCTCAAAATGGGAACGGAATGAGAAGAAACCCTCAGGG
GCTGCGCTACGTCTTCTCAATATAATCAACGAGAAAGGTCTGGATATTTTTGCCAGTTAG