Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1549138..1549372 | Replicon | chromosome |
| Accession | NZ_CP034931 | ||
| Organism | Shigella flexneri strain 2013C-3749 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1549268..1549371 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1549138..1549372 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EPD86_RS07890 | 1545693..1546355 | - | 663 | WP_000944268.1 | exodeoxyribonuclease X | - |
| EPD86_RS07895 | 1546379..1547035 | - | 657 | Protein_1525 | carbon-nitrogen hydrolase family protein | - |
| EPD86_RS07900 | 1547137..1547367 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| EPD86_RS07905 | 1547506..1547880 | + | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| EPD86_RS07910 | 1547884..1548756 | + | 873 | Protein_1528 | copper homeostasis membrane protein CopD | - |
| EPD86_RS07915 | 1548769..1549110 | + | 342 | WP_000976476.1 | YebY family protein | - |
| - | 1549138..1549372 | - | 235 | - | - | Antitoxin |
| - | 1549268..1549371 | + | 104 | - | - | Toxin |
| EPD86_RS25665 | 1549503..1550580 | - | 1078 | Protein_1530 | phage integrase Arm DNA-binding domain-containing protein | - |
| EPD86_RS07930 | 1550546..1550827 | - | 282 | WP_005127484.1 | excisionase | - |
| EPD86_RS07935 | 1550944..1551792 | - | 849 | Protein_1532 | IS3-like element IS600 family transposase | - |
| EPD86_RS07940 | 1551847..1553042 | + | 1196 | Protein_1533 | IS3 family transposase | - |
| EPD86_RS07945 | 1553085..1553395 | - | 311 | Protein_1534 | transposase | - |
| EPD86_RS07950 | 1553459..1553926 | + | 468 | Protein_1535 | DNA-binding transcriptional regulator PgrR | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T116942 NZ_CP034931:1549268-1549371 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT116942 NZ_CP034931:c1549372-1549138 [Shigella flexneri]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
