Detailed information of TA system TA116935

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-Xre
• Location: 1832456..1833336
• Replicon: chromosome
• Accession: NZ_CP034910
• Organism: Ensifer alkalisoli strain YIC4027

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: EKH55_RS26325
• Protein ID: WP_151613765.1
• Coordinates: 1832456..1832965 (-)
• Length: 170 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: A0A1E3VGG3
• Locus tag: EKH55_RS26330
• Protein ID: WP_069457180.1
• Coordinates: 1832965..1833336 (-)
• Length: 124 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EKH55_RS26305	1827784..1828671	+	888	WP_151613761.1	sulfate ABC transporter permease subunit CysW	-
EKH55_RS26310	1828686..1829795	+	1110	WP_151613762.1	sulfate/molybdate ABC transporter ATP-binding protein	-
EKH55_RS26315	1830175..1831200	+	1026	WP_151613763.1	sulfate ABC transporter substrate-binding protein	-
EKH55_RS26320	1831262..1832305	+	1044	WP_151613764.1	sulfate/molybdate ABC transporter ATP-binding protein	-
EKH55_RS26325	1832456..1832965	-	510	WP_151613765.1	RES domain-containing protein	Toxin
EKH55_RS26330	1832965..1833336	-	372	WP_069457180.1	MbcA/ParS/Xre antitoxin family protein	Antitoxin
EKH55_RS26335	1833415..1834200	-	786	WP_151613766.1	crotonase/enoyl-CoA hydratase family protein	-
EKH55_RS26340	1834197..1835066	-	870	WP_151613767.1	hydroxymethylglutaryl-CoA lyase	-
EKH55_RS26345	1835066..1837054	-	1989	WP_151613768.1	acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha	-
EKH55_RS26350	1837071..1837454	-	384	WP_069457176.1	RidA family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (9-162)

Antitoxin

• Antitoxin Xre/MbcA/ParS-like, toxin-binding domain (71-120)

Sequences

Toxin

Protein

• Length: 170 a.a.
• Molecular weight: 18773.34 Da
• Isoelectric Point: 6.4892

>T116935 WP_151613765.1 NZ_CP034910:c1832965-1832456 [Ensifer alkalisoli]
MTPAEPTELWRAFVPRWAHMPLSGEGAARFGGRWNPIGTPTIYAARELSTAWAEYNQGFVQHPALIVKLELRDAKLADLT
DAGVLAELDLEEAIHRCEWREELDRGVAPQTHTVHANLLARGFHGVIYPSFMSPGGTCAALWRWNGKNGPRLDVVDPEGR
LPKSPASWI

Nucleotide

• Length: 510 bp

>T116935 NZ_CP034910:c1832965-1832456 [Ensifer alkalisoli]
ATGACGCCAGCCGAGCCGACGGAGCTCTGGCGCGCCTTCGTGCCGCGCTGGGCGCATATGCCGCTTTCCGGTGAGGGTGC
CGCCCGATTCGGCGGCCGATGGAATCCGATCGGCACGCCGACCATCTATGCGGCGCGCGAGCTTTCCACCGCCTGGGCGG
AATACAATCAGGGTTTCGTCCAGCATCCGGCACTTATCGTGAAGCTGGAACTGCGTGACGCGAAGCTTGCAGACCTTACC
GACGCCGGCGTGCTCGCCGAGCTTGACCTTGAGGAGGCCATTCACCGCTGCGAATGGCGCGAGGAACTCGACCGCGGAGT
GGCGCCGCAGACGCACACCGTGCACGCGAACCTCCTCGCCCGCGGGTTTCACGGCGTGATCTACCCGTCCTTCATGTCGC
CCGGCGGCACCTGTGCCGCGCTCTGGCGCTGGAATGGCAAGAATGGACCGAGGCTCGACGTCGTCGATCCCGAGGGCCGG
CTGCCAAAGTCGCCGGCGTCGTGGATTTAG

Antitoxin

Protein

• Length: 124 a.a.
• Molecular weight: 13180.20 Da
• Isoelectric Point: 8.5234

>AT116935 WP_069457180.1 NZ_CP034910:c1833336-1832965 [Ensifer alkalisoli]
MIAVDFDITAARFGEDHSPYLSARLVADRLGVTLAELAKLIGVARNTLTAKSGVRKVDSALSQVVRILAMASEMAGDETR
AVIWFKHQPIPGWAGKTAHDLVGEGKADKVLAYLESVRAGVYS

Nucleotide

• Length: 372 bp

>AT116935 NZ_CP034910:c1833336-1832965 [Ensifer alkalisoli]
ATGATCGCTGTCGATTTCGACATTACCGCTGCGCGCTTCGGAGAGGACCACTCGCCGTATCTGTCGGCCCGCCTGGTTGC
CGACCGGCTGGGCGTGACGCTCGCGGAACTCGCCAAGCTGATCGGCGTCGCCCGCAACACCTTGACCGCCAAGTCCGGGG
TGCGGAAGGTCGACAGCGCGCTGAGCCAGGTCGTGCGCATCCTTGCAATGGCATCGGAAATGGCGGGGGACGAGACCCGT
GCCGTCATCTGGTTCAAGCATCAGCCGATCCCGGGCTGGGCCGGGAAGACGGCCCATGACCTGGTGGGCGAAGGCAAGGC
CGACAAGGTGCTTGCCTATCTCGAGTCCGTGCGCGCCGGCGTCTATTCCTGA

Structures

Antitoxin

• AlphaFold DB: A0A1E3VGG3