Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 937142..937782 Replicon chromosome
Accession NZ_CP034910
Organism Ensifer alkalisoli strain YIC4027

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag EKH55_RS22005 Protein ID WP_151613148.1
Coordinates 937142..937528 (-) Length 129 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag EKH55_RS22010 Protein ID WP_151613149.1
Coordinates 937528..937782 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EKH55_RS21975 932662..933453 + 792 WP_151613144.1 3-methyl-2-oxobutanoate hydroxymethyltransferase -
EKH55_RS21980 933658..934542 + 885 WP_151613145.1 formyltetrahydrofolate deformylase -
EKH55_RS21985 934947..935102 + 156 WP_192803866.1 hypothetical protein -
EKH55_RS21990 935267..935473 + 207 WP_151613146.1 cold-shock protein -
EKH55_RS21995 935564..936739 - 1176 WP_151613147.1 site-specific integrase -
EKH55_RS22000 936810..937114 + 305 Protein_860 type II toxin-antitoxin system Phd/YefM family antitoxin -
EKH55_RS22005 937142..937528 - 387 WP_151613148.1 type II toxin-antitoxin system VapC family toxin Toxin
EKH55_RS22010 937528..937782 - 255 WP_151613149.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
EKH55_RS22015 937998..938366 + 369 WP_151613150.1 hypothetical protein -
EKH55_RS22020 938758..939351 + 594 WP_151613151.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein -
EKH55_RS22025 939344..940383 + 1040 Protein_865 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
EKH55_RS22035 940917..941251 + 335 Protein_866 IS5/IS1182 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-124)

Antitoxin

Antitoxin VapB-like

(1-83)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 14066.00 Da        Isoelectric Point: 4.6168

>T116933 WP_151613148.1 NZ_CP034910:c937528-937142 [Ensifer alkalisoli]
MVIDTSAIVAIAFNEPEAETYEQKVVDAPRRFISAATVLELAIVIEARLGEAGAAELDLWLYKAGVEIVAVDAEQIAVAR
RAWRSYGKGRHPASLNYGDCFSYALAKMRNEPLLYKGNDFSRTDIEAA

Download         Length: 387 bp

>T116933 NZ_CP034910:c937528-937142 [Ensifer alkalisoli]
ATGGTCATCGACACCTCCGCCATCGTCGCGATCGCCTTCAACGAGCCGGAAGCAGAAACCTACGAACAAAAAGTCGTCGA
CGCTCCACGGCGCTTCATCTCGGCGGCGACAGTCCTTGAACTCGCCATCGTCATCGAGGCGCGCCTCGGCGAGGCAGGTG
CCGCAGAGCTCGATCTATGGCTTTACAAGGCGGGAGTCGAAATCGTCGCCGTCGACGCGGAACAGATCGCGGTGGCAAGG
CGAGCCTGGCGCAGCTATGGCAAGGGCCGACATCCGGCCAGTCTGAACTATGGCGATTGTTTCTCCTATGCGCTGGCCAA
GATGCGCAATGAACCGCTGCTCTACAAAGGCAATGATTTCTCGCGCACGGACATCGAGGCGGCATGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9392.68 Da        Isoelectric Point: 6.3721

>AT116933 WP_151613149.1 NZ_CP034910:c937782-937528 [Ensifer alkalisoli]
MALSIKDVETERLAKALAEKTGETITMATRRALEERLRRLANAGNRDVLLDELAASRKRWARLPVVDNRSADEILGYDEN
GLPS

Download         Length: 255 bp

>AT116933 NZ_CP034910:c937782-937528 [Ensifer alkalisoli]
ATGGCGCTCAGCATCAAAGACGTCGAGACGGAACGCCTCGCCAAGGCGTTGGCCGAGAAAACTGGTGAAACCATTACCAT
GGCGACTCGCCGGGCACTCGAAGAACGGCTGCGGCGCCTGGCAAACGCCGGAAATCGCGATGTCCTACTCGACGAGCTTG
CCGCCAGCCGGAAGCGCTGGGCCAGGCTGCCGGTTGTCGACAACCGCTCCGCCGACGAGATCTTGGGGTATGACGAAAAC
GGGCTCCCCAGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References