Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 350355..350890 Replicon chromosome
Accession NZ_CP034910
Organism Ensifer alkalisoli strain YIC4027

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag EKH55_RS19280 Protein ID WP_151613883.1
Coordinates 350615..350890 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag EKH55_RS19275 Protein ID WP_151612511.1
Coordinates 350355..350615 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EKH55_RS19240 346279..346548 + 270 WP_192803840.1 ribbon-helix-helix domain-containing protein -
EKH55_RS19245 346657..347106 - 450 WP_151612499.1 GFA family protein -
EKH55_RS19250 347103..347567 - 465 WP_151612501.1 SRPBCC domain-containing protein -
EKH55_RS19255 347600..347938 - 339 WP_151612503.1 metalloregulator ArsR/SmtB family transcription factor -
EKH55_RS19260 348067..348480 + 414 WP_151612505.1 CopG family transcriptional regulator -
EKH55_RS19265 348511..349740 + 1230 WP_151612507.1 PHB depolymerase family esterase -
EKH55_RS19270 349793..350185 + 393 WP_151612509.1 GFA family protein -
EKH55_RS19275 350355..350615 + 261 WP_151612511.1 ribbon-helix-helix domain-containing protein Antitoxin
EKH55_RS19280 350615..350890 + 276 WP_151613883.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EKH55_RS19290 351434..354814 + 3381 WP_151612515.1 response regulator -
EKH55_RS19295 354801..355727 + 927 WP_151612516.1 response regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(6-43)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10861.63 Da        Isoelectric Point: 10.6044

>T116932 WP_151613883.1 NZ_CP034910:350615-350890 [Ensifer alkalisoli]
MQLMWTTKAVSDLGRLYDILAPVNRLAAARTVRSLTAAPKRLLEQLRLGERLEEFEPREVRRVLVGHYEIRYEIQQSTIY
VLRLWHTRENR

Download         Length: 276 bp

>T116932 NZ_CP034910:350615-350890 [Ensifer alkalisoli]
ATGCAGCTCATGTGGACGACCAAGGCGGTTTCCGACCTCGGCCGCCTGTATGATATTCTCGCACCGGTCAATCGCTTGGC
TGCAGCACGGACGGTGCGGTCTCTGACTGCCGCTCCAAAGCGCCTGCTCGAACAACTGCGCCTTGGCGAACGGCTCGAGG
AATTCGAGCCCCGGGAAGTCCGGCGAGTTCTCGTTGGCCACTATGAGATCCGCTATGAAATCCAGCAGTCGACGATCTAT
GTCTTACGGCTCTGGCACACACGCGAGAACCGCTAG

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9714.90 Da        Isoelectric Point: 4.4964

>AT116932 WP_151612511.1 NZ_CP034910:350355-350615 [Ensifer alkalisoli]
METKVLTAHVPRPLAEKVDEIAARLQRSRGWIVKQALSAWIDQEEERRRLTLEALADVDDGHFIDQQAVEAWANSLDSDT
PLQPPA

Download         Length: 261 bp

>AT116932 NZ_CP034910:350355-350615 [Ensifer alkalisoli]
ATGGAGACAAAGGTCTTAACGGCTCACGTGCCGCGACCGCTGGCCGAGAAGGTGGACGAGATCGCGGCGCGACTCCAACG
CTCGCGCGGCTGGATTGTCAAGCAGGCGCTGTCTGCCTGGATTGATCAAGAAGAAGAGCGCCGGCGCCTGACGCTGGAGG
CGCTGGCGGATGTGGACGACGGCCACTTTATTGATCAGCAGGCTGTTGAAGCCTGGGCCAACAGCCTCGACAGCGATACG
CCTCTGCAGCCGCCGGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References