116911

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 3361443..3363154 Replicon chromosome
Accession NZ_CP034836
Organism Hahella sp. KA22

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag ENC22_RS15025 Protein ID WP_127970514.1
Coordinates 3361443..3362087 (+) Length 215 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag ENC22_RS15030 Protein ID WP_127970515.1
Coordinates 3362087..3363154 (+) Length 356 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ENC22_RS15005 3356458..3357468 + 1011 WP_206618099.1 substrate-binding domain-containing protein -
ENC22_RS15010 3357535..3359019 - 1485 WP_127970512.1 ricin-type beta-trefoil lectin domain protein -
ENC22_RS15015 3359559..3360350 + 792 WP_127974507.1 DUF429 domain-containing protein -
ENC22_RS15020 3360839..3361438 + 600 WP_127970513.1 DUF4433 domain-containing protein -
ENC22_RS15025 3361443..3362087 + 645 WP_127970514.1 DUF4433 domain-containing protein Toxin
ENC22_RS15030 3362087..3363154 + 1068 WP_127970515.1 macro domain-containing protein Antitoxin
ENC22_RS15035 3363197..3365014 - 1818 WP_164887278.1 tetratricopeptide repeat protein -
ENC22_RS15040 3365133..3366164 - 1032 WP_127970517.1 VWA domain-containing protein -
ENC22_RS15045 3366677..3367210 - 534 WP_127970518.1 hypothetical protein -
ENC22_RS15050 3367432..3367866 + 435 WP_127970519.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(14-214)

Antitoxin

Macro domain

(18-130)


Sequences

Toxin        


Download         Length: 215 a.a.        Molecular weight: 24902.36 Da        Isoelectric Point: 6.9658

>T116911 WP_127970514.1 NZ_CP034836:3361443-3362087 [Hahella sp. KA22]
MIYTSLNPQKALIWRIVHRENVPWILDHGLHCGNSPVSSSNWVSIGNPELTDKRATHAVPVGPKGYLNDYVPFYFTPFSP
MMKNIHSGWGGIKQRPNEEIVILVSDLYRVSEMGLPFVFTNGHAYYAWTDFFTDLDDLENIDWTIIQSRDFKRDPNDPAK
FERYQAEALIHQSCPVDALKGMVCYTENTKKRLDGWLHERQMAMPVHARPRWYF

Download         Length: 645 bp

>T116911 NZ_CP034836:3361443-3362087 [Hahella sp. KA22]
ATGATCTATACCAGTTTGAACCCACAGAAAGCGCTCATCTGGCGCATTGTTCATCGTGAAAATGTTCCTTGGATTCTAGA
CCACGGTTTGCACTGTGGAAACAGTCCAGTTAGCTCGTCTAATTGGGTGAGTATTGGTAATCCTGAGTTAACTGACAAAC
GCGCGACGCATGCAGTTCCCGTGGGGCCAAAAGGATACTTGAATGACTATGTGCCTTTCTATTTCACTCCGTTCTCCCCA
ATGATGAAAAATATTCACAGCGGATGGGGAGGAATTAAACAGCGGCCGAATGAGGAGATTGTAATTCTCGTTTCCGACTT
GTACCGTGTCAGCGAAATGGGGCTACCCTTTGTTTTTACCAATGGGCATGCATATTACGCTTGGACCGACTTCTTCACTG
ACCTAGACGACCTAGAAAATATTGATTGGACTATTATCCAGTCCAGAGATTTCAAGCGAGACCCTAATGACCCAGCCAAA
TTCGAGCGATATCAGGCTGAGGCACTGATACATCAATCTTGTCCAGTCGATGCCTTAAAGGGCATGGTTTGTTACACTGA
AAACACAAAAAAACGATTGGATGGTTGGTTGCACGAGCGACAAATGGCCATGCCAGTTCATGCGCGGCCAAGGTGGTATT
TCTAA

Antitoxin


Download         Length: 356 a.a.        Molecular weight: 40215.21 Da        Isoelectric Point: 6.2639

>AT116911 WP_127970515.1 NZ_CP034836:3362087-3363154 [Hahella sp. KA22]
MISYAQGNLLEAEVEALVNTVNTVGVMGKGIALMFKERFPQNMQAYVRACRTGDVVTGKMFITKTDELMGPKWIVNFPTK
QHWRAKSKMEWIDEGLVDLRRFITEHHVKSIAIPPLGAGNGGLSWQDVKRRIEKALTDIEGVDIRVYEPTAKYQNVSKKA
GVSELTTSRAMVAELVRRYWILGMECSLLEIQKLAWFLQRVIDAQGLKNDLELHFEANYYGPYANNLTHLLNALDGSYLK
SDKRIPDSDPLDVIAFNDTKREYVETYLNTEGQDYLPALEKASEIISGFESPFGMELLATVDWLLTREGCEPTLESIKGG
IAHWPSGKKWAERKLALFDDRSLQFAIDRMKTASI

Download         Length: 1068 bp

>AT116911 NZ_CP034836:3362087-3363154 [Hahella sp. KA22]
ATGATTTCGTATGCACAAGGTAATTTACTTGAGGCGGAAGTGGAAGCGCTGGTGAATACCGTAAATACCGTTGGAGTGAT
GGGAAAGGGCATTGCTCTGATGTTTAAAGAGCGCTTTCCGCAAAATATGCAGGCTTATGTCAGGGCCTGTAGAACAGGAG
ATGTGGTCACAGGGAAGATGTTCATCACTAAAACAGACGAGCTGATGGGGCCGAAGTGGATTGTTAATTTCCCAACGAAG
CAGCATTGGCGCGCAAAGTCCAAAATGGAGTGGATTGATGAGGGGCTTGTGGATTTGCGTCGATTTATTACAGAACACCA
TGTAAAGTCAATTGCAATCCCCCCGTTAGGTGCCGGTAATGGTGGTTTAAGCTGGCAGGACGTGAAGCGCCGCATTGAAA
AAGCCCTTACTGATATTGAGGGCGTCGATATTCGGGTTTATGAACCCACAGCAAAATATCAAAACGTTTCAAAAAAGGCG
GGTGTAAGCGAGCTTACCACTTCACGAGCAATGGTCGCTGAACTTGTGCGTCGCTATTGGATACTCGGTATGGAGTGCAG
CTTACTCGAAATTCAAAAGCTTGCTTGGTTTTTACAGCGAGTAATTGATGCGCAAGGTTTAAAAAATGACTTGGAGCTTC
ATTTTGAAGCCAATTACTACGGGCCTTACGCTAATAACTTAACTCATTTATTGAATGCTCTAGATGGTAGCTACCTTAAG
TCTGATAAGCGCATTCCTGACAGTGACCCTCTGGACGTCATCGCTTTTAACGATACCAAAAGAGAATACGTTGAAACTTA
TTTGAATACTGAGGGGCAGGATTATTTGCCTGCATTAGAAAAAGCCAGCGAGATAATTAGTGGCTTTGAATCGCCCTTTG
GGATGGAGTTGCTTGCCACTGTTGACTGGTTGCTAACAAGAGAAGGGTGCGAACCTACTTTGGAGTCCATTAAGGGCGGT
ATTGCTCATTGGCCATCAGGAAAGAAATGGGCTGAGCGCAAGCTTGCTTTATTTGATGACAGAAGCTTGCAATTCGCAAT
AGATCGAATGAAGACGGCTTCAATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References