Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 4524594..4526311 Replicon chromosome
Accession NZ_CP034783
Organism Pseudomonas sp. MPC6

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag ELQ88_RS22975 Protein ID WP_138967975.1
Coordinates 4524594..4525478 (+) Length 295 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag ELQ88_RS22980 Protein ID WP_138967977.1
Coordinates 4525475..4526311 (+) Length 279 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ELQ88_RS22950 4520551..4521402 + 852 WP_082930372.1 ABC transporter ATP-binding protein -
ELQ88_RS22955 4521442..4522443 + 1002 WP_138967969.1 ABC transporter substrate-binding protein -
ELQ88_RS22960 4522472..4523248 + 777 WP_064678597.1 ABC transporter permease -
ELQ88_RS22965 4523245..4524012 + 768 WP_178084709.1 SDR family oxidoreductase -
ELQ88_RS22970 4524026..4524589 + 564 WP_138967973.1 cupin domain-containing protein -
ELQ88_RS22975 4524594..4525478 + 885 WP_138967975.1 alpha/beta hydrolase Toxin
ELQ88_RS22980 4525475..4526311 + 837 WP_138967977.1 IclR family transcriptional regulator Antitoxin
ELQ88_RS22985 4526313..4527110 + 798 WP_138967979.1 SDR family oxidoreductase -
ELQ88_RS22990 4527103..4528785 + 1683 WP_138967981.1 thiamine pyrophosphate-binding protein -
ELQ88_RS22995 4528796..4529599 + 804 WP_138967983.1 aspartate dehydrogenase -
ELQ88_RS23000 4529610..4531106 + 1497 WP_138967985.1 aldehyde dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Alpha/beta hydrolase fold-1

(47-278)

Antitoxin

Transcription regulator IclR, N-terminal

(19-68)


Sequences

Toxin        


Download         Length: 295 a.a.        Molecular weight: 31186.79 Da        Isoelectric Point: 6.8094

>T116515 WP_138967975.1 NZ_CP034783:4524594-4525478 [Pseudomonas sp. MPC6]
MLHAIDTLAPPLTADLQAQLALHFPQRTLELAGARQAVRECGAGPAIVLLHGIGSGSASWLQVAQELGQSARVIAWDAPG
YGDSTPLRALAPDASDYAERLLQMLDALDIQRCVLVGHSLGAITATAFASGVHQQRISRLVLISPAQGYGHPSRALQRQD
VRNKRLRALEQLGIPGMAEQRSAYMLSPHASPKAQAWVQWNMARLNPEGYRQAIELLCGDDLLRHAPLSMPCEVHCGEAD
GITAPESCLTLAKALGGTFNLIADAGHASPIEQPCVVAGRLACAIKESLTGASL

Download         Length: 885 bp

>T116515 NZ_CP034783:4524594-4525478 [Pseudomonas sp. MPC6]
ATGTTGCACGCCATCGATACCCTCGCCCCGCCGCTCACGGCCGACCTCCAGGCCCAGTTGGCGCTGCACTTCCCCCAGCG
CACGCTGGAGCTCGCAGGCGCCCGCCAGGCCGTGCGCGAATGCGGGGCCGGGCCGGCCATCGTGTTGCTGCACGGGATCG
GCTCGGGCTCGGCGTCGTGGCTGCAAGTGGCGCAGGAGTTGGGCCAAAGTGCCCGGGTGATCGCCTGGGACGCGCCCGGC
TATGGCGACTCTACGCCGCTCAGGGCCTTGGCCCCGGACGCTTCGGACTACGCCGAACGGCTGCTGCAGATGCTCGACGC
CCTGGACATCCAGCGCTGTGTGCTGGTGGGTCACTCCCTGGGGGCGATCACCGCCACCGCGTTCGCCAGCGGCGTGCACC
AGCAGCGCATCAGCCGCCTGGTCTTGATCAGCCCGGCCCAGGGCTACGGCCATCCGTCGCGCGCCTTGCAACGCCAGGAC
GTGCGCAACAAACGCCTGCGCGCCCTGGAGCAACTGGGCATCCCGGGCATGGCCGAGCAACGCAGTGCCTACATGCTCTC
GCCCCACGCCAGCCCCAAGGCACAGGCCTGGGTGCAGTGGAACATGGCCCGGCTCAATCCCGAGGGCTATCGCCAGGCCA
TCGAGCTGCTGTGCGGCGATGACCTGCTGCGCCACGCGCCGCTGTCGATGCCGTGCGAAGTGCATTGCGGCGAAGCCGAC
GGCATCACCGCGCCCGAAAGCTGCCTGACCCTGGCCAAGGCCCTGGGCGGCACGTTCAACCTTATCGCCGATGCCGGGCA
CGCCAGCCCCATCGAACAACCTTGTGTGGTGGCGGGCCGTCTGGCCTGTGCCATCAAAGAATCCCTGACAGGTGCATCGC
TATGA

Antitoxin


Download         Length: 279 a.a.        Molecular weight: 30893.45 Da        Isoelectric Point: 6.1325

>AT116515 WP_138967977.1 NZ_CP034783:4525475-4526311 [Pseudomonas sp. MPC6]
MNDSDLLKDAQDKYIVPGLERGLLLLCEFSRRNRTLTAPELARRLALPRSTIFRLLTTLETMGFVTRSGNEYRLGMSVLR
LGFEYLASLELTELGQPLLARLCDRLNYPSNLVVRDGRSIVYVAKVSPPSVFSSAVNVGTRLPAHATVLGRILLEDLSLA
ELRELYPEDHLEQFSPCTPKTVMELFDMVQADRQRGFVSGEGFFESAISTVAAPVRDQSGQIVAALGVTIPTTQIAHVNF
NELLLQVRRSADELSRLLDYNSAAGHDGQQRVTALMRD

Download         Length: 837 bp

>AT116515 NZ_CP034783:4525475-4526311 [Pseudomonas sp. MPC6]
ATGAACGATTCAGATCTGCTGAAGGACGCTCAGGACAAATACATCGTGCCGGGCCTGGAGCGCGGCCTGCTGCTGCTCTG
CGAGTTCAGCCGGCGCAACCGCACGCTGACCGCGCCGGAACTGGCCCGGCGCCTGGCGCTGCCGCGCTCGACGATTTTCC
GCTTGCTGACGACCCTGGAAACCATGGGCTTCGTCACCCGCAGCGGCAATGAATATCGCCTGGGCATGTCGGTGCTGCGC
CTGGGCTTCGAGTACCTGGCCTCGCTGGAGCTGACCGAACTCGGCCAGCCGCTGCTGGCCCGCCTGTGCGACCGCCTCAA
CTACCCGAGCAACCTGGTGGTGCGCGACGGCCGTTCGATCGTCTACGTGGCCAAGGTCTCGCCGCCGTCGGTGTTCTCCA
GCGCGGTGAATGTCGGCACCCGCCTGCCCGCCCACGCCACGGTCCTGGGGCGCATCCTGCTCGAAGACCTGTCGCTGGCC
GAGCTGCGCGAGCTGTACCCGGAAGATCACCTGGAGCAGTTCTCGCCCTGCACGCCGAAAACCGTGATGGAGCTGTTCGA
CATGGTCCAGGCCGACCGTCAGCGCGGGTTTGTCAGCGGTGAAGGCTTCTTCGAGTCAGCGATTTCGACCGTTGCCGCAC
CGGTGCGCGATCAATCCGGGCAGATCGTCGCGGCCCTGGGCGTGACCATTCCGACCACGCAAATCGCCCACGTCAACTTC
AACGAATTGCTCCTGCAGGTGCGTCGCAGCGCCGACGAGCTGTCGCGGTTGCTCGACTACAACAGCGCGGCCGGCCACGA
CGGCCAGCAGCGCGTGACCGCCCTGATGAGGGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References