Detailed information of TA system TA116514

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-TIGR02293
• Location: 4320754..4321646
• Replicon: chromosome
• Accession: NZ_CP034783
• Organism: Pseudomonas sp. MPC6

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: ELQ88_RS22005
• Protein ID: WP_138967718.1
• Coordinates: 4321200..4321646 (+)
• Length: 149 a.a.

Antitoxin (Protein)

• Gene name: PrcA
• Uniprot ID: -
• Locus tag: ELQ88_RS22000
• Protein ID: WP_128871629.1
• Coordinates: 4320754..4321203 (+)
• Length: 150 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ELQ88_RS21975	4315840..4316892	+	1053	WP_138967710.1	ABC transporter substrate-binding protein	-
ELQ88_RS21980	4316908..4317975	+	1068	WP_138967712.1	ABC transporter ATP-binding protein	-
ELQ88_RS21985	4317972..4318814	+	843	WP_138967714.1	ABC transporter permease	-
ELQ88_RS21990	4318811..4319599	+	789	WP_128871631.1	ABC transporter permease	-
ELQ88_RS21995	4319635..4320648	+	1014	WP_138967716.1	proline racemase family protein	-
ELQ88_RS22000	4320754..4321203	+	450	WP_128871629.1	DUF2384 domain-containing protein	Antitoxin
ELQ88_RS22005	4321200..4321646	+	447	WP_138967718.1	RES family NAD+ phosphorylase	Toxin
ELQ88_RS22010	4321704..4325984	-	4281	WP_161599978.1	cytochrome P450	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (3-138)

Antitoxin

• Antitoxin Xre (28-146)

Sequences

Toxin

Protein

• Length: 149 a.a.
• Molecular weight: 16254.98 Da
• Isoelectric Point: 5.9761

>T116514 WP_138967718.1 NZ_CP034783:4321200-4321646 [Pseudomonas sp. MPC6]
MIFWRISAFADLTGRGGILAGGRWHTAGRPVVYLAGTPAGAMLEILVHLEIDQEDLPETLQLLKVEVPDDISLAPAPALK
PDWEFEPNHTKGIGDAFLKGCPALLLPVPSAIMPHSLNYLFNPMHLDSVKAIITAEPFRLDNRLIRKT

Nucleotide

• Length: 447 bp

>T116514 NZ_CP034783:4321200-4321646 [Pseudomonas sp. MPC6]
TTGATCTTTTGGCGAATCAGCGCTTTTGCGGATCTGACCGGACGTGGCGGCATCCTCGCGGGGGGGCGCTGGCACACGGC
GGGGAGACCGGTGGTCTATCTGGCGGGGACACCTGCCGGTGCAATGCTCGAGATACTGGTACACCTTGAGATCGATCAGG
AAGACCTCCCGGAGACGCTCCAGTTGCTCAAAGTCGAGGTGCCCGACGATATCAGCCTCGCCCCTGCCCCGGCACTCAAG
CCGGATTGGGAATTCGAGCCGAACCACACCAAGGGCATTGGCGATGCATTCCTGAAAGGATGCCCTGCCCTGCTGTTGCC
GGTACCGAGCGCTATCATGCCGCATTCGCTGAACTACCTGTTCAACCCCATGCACCTCGACTCGGTCAAGGCCATCATTA
CCGCTGAGCCGTTCAGGCTCGACAACCGACTGATCAGGAAAACGTAA

Antitoxin

Protein

• Length: 150 a.a.
• Molecular weight: 16707.21 Da
• Isoelectric Point: 6.4880

>AT116514 WP_128871629.1 NZ_CP034783:4320754-4321203 [Pseudomonas sp. MPC6]
MLAEIMREPAYGAYRARLHALLQIPTDASDLEIHDIIQIGFAAGRLVSLCEQGELTPLERDQIIPLKTLKTRVAKDQHLT
VDESDRLFRAAHITAMADAVFGNDEKAKRWLSKPKDRFSGRSPMAMLSTVQGTRQVEETLIQLAEGYAF

Nucleotide

• Length: 450 bp

>AT116514 NZ_CP034783:4320754-4321203 [Pseudomonas sp. MPC6]
ATGCTGGCTGAAATCATGCGTGAACCCGCCTACGGTGCCTACCGCGCTCGGCTGCACGCCTTGCTGCAAATTCCCACCGA
TGCGTCTGACCTGGAAATCCACGACATCATCCAGATCGGCTTTGCGGCTGGCCGTCTTGTGTCACTCTGCGAACAGGGTG
AACTGACGCCGCTGGAGCGCGACCAGATCATCCCCTTGAAAACGCTGAAGACCCGGGTGGCTAAAGACCAGCACCTCACG
GTCGACGAGAGTGATCGCCTGTTCCGCGCCGCCCACATCACCGCCATGGCAGACGCTGTATTTGGCAACGATGAAAAAGC
CAAACGCTGGCTGTCGAAACCCAAGGACCGGTTTTCGGGCCGTAGCCCAATGGCAATGCTGTCGACGGTACAGGGAACAC
GCCAGGTTGAGGAAACACTGATCCAGTTGGCCGAAGGCTACGCCTTTTGA