Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 435748..436385 Replicon chromosome
Accession NZ_CP034783
Organism Pseudomonas sp. MPC6

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag ELQ88_RS03980 Protein ID WP_138963768.1
Coordinates 435748..436155 (-) Length 136 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag ELQ88_RS03985 Protein ID WP_128873801.1
Coordinates 436155..436385 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ELQ88_RS03960 431410..432105 - 696 WP_128873806.1 ABC transporter permease -
ELQ88_RS03965 432184..432930 - 747 WP_128873805.1 ABC transporter substrate-binding protein -
ELQ88_RS03970 432944..433717 - 774 WP_128873804.1 ABC transporter ATP-binding protein -
ELQ88_RS03975 434280..435671 + 1392 WP_138963766.1 GABA permease -
ELQ88_RS03980 435748..436155 - 408 WP_138963768.1 tRNA(fMet)-specific endonuclease VapC Toxin
ELQ88_RS03985 436155..436385 - 231 WP_128873801.1 antitoxin Antitoxin
ELQ88_RS03990 436570..437022 - 453 WP_138963770.1 hypothetical protein -
ELQ88_RS03995 437029..437445 - 417 WP_138963772.1 hypothetical protein -
ELQ88_RS04000 437483..438457 - 975 WP_128873799.1 alpha/beta fold hydrolase -
ELQ88_RS04005 438506..438766 - 261 Protein_401 DUF1016 family protein -
ELQ88_RS04010 438888..439259 + 372 Protein_402 carboxypeptidase regulatory-like domain-containing protein -
ELQ88_RS04015 439401..439838 - 438 WP_128873932.1 hypothetical protein -
ELQ88_RS04025 440249..440521 - 273 WP_064675437.1 oxidative damage protection protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 425532..436385 10853


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-124)

Antitoxin

SpoVT-AbrB domain

(7-34)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15060.48 Da        Isoelectric Point: 6.8622

>T116512 WP_138963768.1 NZ_CP034783:c436155-435748 [Pseudomonas sp. MPC6]
MIKFMLDTNICIFTIKNKPQIVREAFNRHNGQMCISAVTLMELIYGAEKSAAPEKNLAMIEGLAARLEVLPFDNEAAAHT
GMIRSELAKAGTPIGPYDYMIAGHARSRGYIVVTNNLREFEQVPGLRVEDWVHPT

Download         Length: 408 bp

>T116512 NZ_CP034783:c436155-435748 [Pseudomonas sp. MPC6]
ATGATCAAGTTCATGCTCGATACCAACATTTGCATCTTCACGATCAAGAACAAGCCGCAAATCGTACGAGAAGCTTTCAA
CCGTCATAACGGGCAAATGTGTATCAGTGCTGTCACGCTGATGGAGTTGATCTACGGTGCCGAAAAATCAGCAGCGCCCG
AAAAGAACCTTGCCATGATCGAGGGTTTGGCAGCCCGCCTTGAGGTCTTGCCTTTCGACAATGAAGCAGCTGCACACACC
GGAATGATTCGGTCCGAGCTGGCAAAGGCTGGAACGCCCATTGGCCCCTATGACTACATGATTGCCGGGCACGCGCGCTC
ACGCGGCTACATTGTGGTAACCAACAATCTGCGGGAGTTCGAACAGGTCCCGGGATTACGCGTAGAGGACTGGGTTCACC
CCACCTGA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8519.52 Da        Isoelectric Point: 4.3569

>AT116512 WP_128873801.1 NZ_CP034783:c436385-436155 [Pseudomonas sp. MPC6]
MEQTTLFMSNRSQAVRLPKAVAMPSDVKRVDVVAIGRARIITPAGETWDSWFDGDGVSADFMTDREQPADQERESF

Download         Length: 231 bp

>AT116512 NZ_CP034783:c436385-436155 [Pseudomonas sp. MPC6]
ATGGAACAGACAACCCTTTTCATGAGCAATCGAAGCCAGGCCGTCCGCCTTCCCAAAGCTGTTGCAATGCCAAGTGACGT
GAAACGAGTCGACGTAGTCGCTATTGGCAGGGCTCGCATCATCACCCCCGCCGGTGAAACATGGGACAGCTGGTTCGATG
GGGATGGTGTGAGTGCAGACTTCATGACCGACCGGGAACAACCCGCCGATCAGGAGCGTGAGTCGTTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References