Detailed information of TA system TA116511

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): slvAT/RES(toxin)
• Location: 267339..268230
• Replicon: plasmid pMPC6-328K
• Accession: NZ_CP034782
• Organism: Pseudomonas sp. MPC6

Toxin (Protein)

• Gene name: slvT
• Uniprot ID: -
• Locus tag: ELQ88_RS01580
• Protein ID: WP_138963216.1
• Coordinates: 267339..267791 (-)
• Length: 151 a.a.

Antitoxin (Protein)

• Gene name: slvA
• Uniprot ID: -
• Locus tag: ELQ88_RS01585
• Protein ID: WP_138963218.1
• Coordinates: 267859..268230 (-)
• Length: 124 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ELQ88_RS01550	262817..263218	-	402	WP_138963206.1	type II toxin-antitoxin system MqsA family antitoxin	-
ELQ88_RS01555	263220..263516	-	297	WP_138963208.1	type II toxin-antitoxin system MqsR family toxin	-
ELQ88_RS01560	263844..264143	+	300	WP_138963210.1	MarR family transcriptional regulator	-
ELQ88_RS01565	264311..265555	+	1245	WP_138963212.1	sulfite oxidase	-
ELQ88_RS01570	265530..265886	+	357	WP_138963214.1	cytochrome c	-
ELQ88_RS01575	266420..266965	-	546	Protein_251	sprT domain-containing protein	-
ELQ88_RS01580	267339..267791	-	453	WP_138963216.1	RES family NAD+ phosphorylase	Toxin
ELQ88_RS01585	267859..268230	-	372	WP_138963218.1	DUF2384 domain-containing protein	Antitoxin
ELQ88_RS01595	269110..270150	-	1041	WP_138963220.1	putative sulfate exporter family transporter	-
ELQ88_RS01600	270265..270591	-	327	WP_138963222.1	NIPSNAP family protein	-
ELQ88_RS01605	270827..272317	-	1491	WP_138963224.1	CoA-acylating methylmalonate-semialdehyde dehydrogenase	-
ELQ88_RS01610	272317..273048	-	732	WP_138963226.1	fumarate hydratase C-terminal domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..328214	328214

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (2-134)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 151 a.a.
• Molecular weight: 16394.45 Da
• Isoelectric Point: 4.3083

>T116511 WP_138963216.1 NZ_CP034782:c267791-267339 [Pseudomonas sp. MPC6]
MPLSGMGAARQGGRFNRPDQEALYLSLDDATALAEYKQDNPWLRPGTICTFFVNGLQVADLSAGFDCERWPSLWADFTVD
WRAEWFDKASEPPTLYMADDVVAAGLDGILFPSQARPVGTNLVIYRSSAKPASQLRVCDPDGVLQGLAGH

Nucleotide

• Length: 453 bp

>T116511 NZ_CP034782:c267791-267339 [Pseudomonas sp. MPC6]
ATGCCGTTATCCGGCATGGGGGCGGCGCGCCAGGGTGGTCGCTTCAACCGCCCTGATCAGGAGGCGTTGTACCTGTCGTT
GGATGATGCGACGGCGCTGGCAGAGTACAAACAGGACAACCCCTGGCTGCGGCCAGGCACGATCTGCACGTTCTTTGTCA
ACGGCCTGCAGGTGGCCGATTTGAGCGCGGGTTTCGACTGCGAGCGCTGGCCGTCGTTGTGGGCTGATTTTACCGTGGAC
TGGCGTGCGGAATGGTTCGACAAGGCCTCGGAGCCGCCGACCTTGTACATGGCCGATGATGTGGTGGCTGCTGGGCTGGA
CGGCATTCTGTTCCCCTCGCAGGCGCGTCCGGTTGGGACCAATCTGGTGATCTACCGCAGCTCTGCCAAGCCTGCGTCGC
AACTGCGCGTCTGTGACCCTGATGGGGTGTTACAGGGGCTCGCGGGGCATTGA

Antitoxin

Protein

• Length: 124 a.a.
• Molecular weight: 13775.69 Da
• Isoelectric Point: 6.4736

>AT116511 WP_138963218.1 NZ_CP034782:c268230-267859 [Pseudomonas sp. MPC6]
MNTVLQEPIVERFREPNTPYLSPSKVSDFFGFRVQELAERAHVHRNTPTARPQAPQLQKYLQDMLRVLAVATEMTGDSER
AVFLLRNEPLRAFSYKTADALIQEGRADALIAYLESLVGGAAG

Nucleotide

• Length: 372 bp

>AT116511 NZ_CP034782:c268230-267859 [Pseudomonas sp. MPC6]
ATGAATACCGTGCTGCAAGAACCCATCGTTGAGCGGTTCCGCGAGCCCAACACCCCGTATCTATCCCCGTCCAAGGTCAG
TGATTTCTTCGGCTTTCGGGTACAGGAGTTGGCCGAGCGCGCGCATGTGCATCGCAATACCCCTACCGCGCGGCCTCAGG
CACCTCAGTTGCAAAAGTACCTGCAGGACATGTTAAGAGTGCTGGCCGTGGCCACCGAGATGACAGGCGACTCCGAGCGG
GCTGTCTTTCTGCTGCGCAATGAGCCGTTGCGGGCCTTCAGTTACAAGACTGCCGATGCCCTGATCCAGGAAGGGCGTGC
CGATGCGCTTATCGCCTATCTGGAGTCTCTCGTGGGCGGTGCCGCGGGATGA